CA4

Gene

CA4

Protein

Carbonic anhydrase 4

Organism

Bos taurus

Length

312 amino acids

Function

Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity).

Similarity

Belongs to the alpha-carbonic anhydrase family.

Mass

35.151 kDa

Sequence

MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAKTQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSRAMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQPLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQKPIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLAPVLACLTVGFLR

Protein

Carbonic anhydrase 4: CA4

Gene

CA4

Protein

Carbonic anhydrase 4

Organism

Homo sapiens

Length

312 amino acids

Function

Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.

Similarity

Belongs to the alpha-carbonic anhydrase family.

Mass

35.032 kDa

Sequence

MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLGPMLACLLAGFLR

Protein

Carbonic anhydrase 4: CA4

Gene

Ca4

Protein

Carbonic anhydrase 4

Organism

Rattus norvegicus

Length

309 amino acids

Function

Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity).

Similarity

Belongs to the alpha-carbonic anhydrase family.

Mass

35.076 kDa

Sequence

MQLLLALLALAYVAPSTEDSHWCYEIQAKEPNSHCSGPEQWTGDCKKNQQSPINIVTSKTKLNPSLTPFTFVGYDQKKKWEVKNNQHSVEMSLGEDIYIFGGDLPTQYKAIQLHLHWSEESNKGSEHSIDGKHFAMEMHVVHKKMTTGDKVQDSDSKDKIAVLAFMVEVGNEVNEGFQPLVEALSRLSKPFTNSTVSESCLQDMLPEKKKLSAYFRYQGSLTTPGCDETVIWTVFEEPIKIHKDQFLEFSKKLYYDQEQKLNMKDNVRPLQPLGNRQVFRSHASGRLLSLPLPTLLVPTLTCLVASFLH

Protein

Carbonic anhydrase 4: Ca4

Gene

CA4

Protein

Carbonic anhydrase 4

Organism

Oryctolagus cuniculus

Length

308 amino acids

Function

Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity).

Similarity

Belongs to the alpha-carbonic anhydrase family.

Mass

34.394 kDa

Sequence

MQLLFALLALGALRPLAGEELHWCYEIQASNYSCLGPDKWQEDCQKSRQSPINIVTTKAEVDHSLGRFHFSGYDQREARLVENNGHSVMVSLGDEISISGGGLPARYRATQLHLHWSQELDRGSEHSLDGERSAMEMHIVHQKETGTSGNEVQDSDDSIAVLAFLVEAGPTMNEGFQPLVTALSAISIPGTNTTMAPSSLWDLLPAEEELRHYFRYMGSLTTPACSETVVWTVFQEPIRLHRDQILEFSSKLYYDQERKMNMKDNVRPLQRLGDRSVFKSQAAGQLLPLPLPTLLVPTLACVMAGLLR

Protein

Carbonic anhydrase 4: CA4

Gene

Ca4

Protein

Carbonic anhydrase 4

Organism

Mus musculus

Length

305 amino acids

Function

Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity).

Similarity

Belongs to the alpha-carbonic anhydrase family.

Mass

34.351 kDa

Sequence

MQLLLALLALAYVAPSTEDSGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQPLGKRQVFKSHAPGQLLSLPLPTLLVPTLTCLVANFLQ

Protein

Carbonic anhydrase 4: Ca4