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C5AR2

Gene
C5ar2
Protein
C5a anaphylatoxin chemotactic receptor 2
Organism
Mus musculus
Length
344 amino acids
Function
Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways (By similarity).
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
38.199 kDa
Sequence
MMNHTTSEYYDYEYDHEHYSDLPDVPVDCPAGTCFTSDVYLIVLLVLYAAVFLVGVPGNTLVAWVTWKESRHRLGASWFLHLTMADLLCCVSLPFLAVPIAQKGHWPYGAAGCWLLSSITILSMYASVLLLTGLSGDLFLLAFRPSWKGADHRTFGVRVVQASSWMLGLLLTVPSAVYRRLLQEHYPPRLVCGIDYGGSVSAEVAITTVRFLFGFLGPLVFMAGCHGILQRQMARRHWPLGTAVVVGFFICWTPYHVLRVIIAAAPPHSLLLARVLEAEPLFNGLALAHSALNPIMFLYFGRKQLCKSLQAACHWALRDPQDEESAVTKVSISTSHEMVSEMPV
Protein
C5a anaphylatoxin chemotactic receptor 2: C5ar2

Gene
C5ar2
Protein
C5a anaphylatoxin chemotactic receptor 2
Organism
Rattus norvegicus
Length
343 amino acids
Function
Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
38.123 kDa
Sequence
MLNDTTSKDYEYEYDQEQYSDLLNVPVDCPAGNCFSNDAYLIVLLGLYSVIFLVGVPGNTLLAWVTWKESRHRLGASWFLHLTMADLLCCVSLPFLAVPIAQKGHWPYGTAGCWLLSSITVLSMYASVLLLTGLSGDLFLLAFRPSWKNADQRTCGVRVVQVSSWMLALLLTVPGAVYRKLLQEHYPPRLVCGTNYGGSVTAEVTITTVRFLFGFLVPLVFMASCHGILQRQMARRHWPLGTAVVVGFFICWTPFHLLRVIIAVASSHSPLLAWALEAEPLVTGLALAHSALNPIMFLYFGRKQLCKSLQAACHWALRDLQDEEESAVTKVSTSQEMVSEMPV
Protein
C5a anaphylatoxin chemotactic receptor 2: C5ar2

Gene
C5AR2
Protein
C5a anaphylatoxin chemotactic receptor 2
Organism
Homo sapiens
Length
337 amino acids
Function
Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways.
Similarity
Belongs to the G-protein coupled receptor 1 family.
Mass
36.08 kDa
Sequence
MGNDSVSYEYGDYSDLSDRPVDCLDGACLAIDPLRVAPLPLYAAIFLVGVPGNAMVAWVAGKVARRRVGATWLLHLAVADLLCCLSLPILAVPIARGGHWPYGAVGCRALPSIILLTMYASVLLLAALSADLCFLALGPAWWSTVQRACGVQVACGAAWTLALLLTVPSAIYRRLHQEHFPARLQCVVDYGGSSSTENAVTAIRFLFGFLGPLVAVASCHSALLCWAARRCRPLGTAIVVGFFVCWAPYHLLGLVLTVAAPNSALLARALRAEPLIVGLALAHSCLNPMLFLYFGRAQLRRSLPAACHWALRESQGQDESVDSKKSTSHDLVSEMEV
Protein
C5a anaphylatoxin chemotactic receptor 2: C5AR2