C23L

Chemokine-binding protein

258 amino acids

Inhibits host immune defense by binding to host chemokines. Binds host CC chemokines (beta chemokines) such as RANTES with high affinity, but not CXC or C chemokines (alpha and gamma chemokines).

Belongs to the poxviridae chemokine-binding protein family.

27.831 kDa

MKQYIVLACMCLAAAAMPASLQQSSSSSSSCTEEENKHHMGIDVIIKVTKQDQTPTNDKICQSVTEITESESDPDPEVESEDDSTSVEDVDPPTTYYSIIGGGLRMNFGFTKCPQIKSISESADGNTVNARLSSVSPGQGKDSPAITREEALAMIKDCEVSIDIRCSEEEKDSDIKTHPVLGSNISHKKVSYEDIIGSTIVDTKCVKNLEFSVRIGDMCKESSELEVKDGFKYVDGSASEGATDDTSLIDSTKLKACV

C23L

Chemokine-binding protein

253 amino acids

Inhibits host immune defense by binding to host chemokines. Binds host CC chemokines (beta chemokines) such as RANTES with high affinity, but not CXC or C chemokines (alpha and gamma chemokines) (By similarity).

Belongs to the poxviridae chemokine-binding protein family.

27.465 kDa

MKQYIVLACMCLAAAAMPASLQQSSSSCTEEENKHYMGIDVIIKVTKQDQTPTNDKICQSVTEITESESDPEVESEDDSTSVEDVDPPTTYYSIIGGGLRMNFGFTKCPQIKSISESANGNAVNARLSSVPLGQGKDSPAITRAEALAMIKDCELSIDIRCSEEEKDSDIQTHPVLESNISHKKVSYEDIIGSTIVDTKCVKNLEFSVRIGDMCKESSDLEVKDGFKYVDGSVSEGVTDDTSLIDSTKLKSCV

C23L

Inactive chemokine-binding protein

244 amino acids

The protein is truncated in this vaccinal strain and presumably inactive, because the lack of signal peptide prevents the protein of being secreted. In the other strains inhibits host immune defense by binding to host chemokines. Binds host CC chemokines (beta chemokines) such as RANTES with high affinity, but not CXC or C chemokines (alpha and gamma chemokines) (By similarity).

Belongs to the poxviridae chemokine-binding protein family.

26.385 kDa

MHVPASLQQSSSSSSSCTEEENKHHMGIDVIIKVTKQDQTPTNDKICQSVTEITESESDPDPEVESEDDSTSVEDVDPPTTYYSIIGGGLRMNFGFTKCPQIKSISESADGNTVNARLSSVSPGQGKDSPAITREEALAMIKDCEVSIDIRCSEEEKDSDIKTHPVLGSNISHKKVSYEDIIGSTIVDTKCVKNLEFSVRIGDMCKESSELEVKDGFKYVDGSASEGATDDTSLIDSTKLKACV

C23L

Inactive chemokine-binding protein

244 amino acids

The protein is truncated in this vaccinal strain and presumably inactive, because the lack of signal peptide prevents the protein of being secreted. In the wild-type viruses inhibits host immune defense by binding to host chemokines. Binds host CC chemokines (beta chemokines) such as RANTES with high affinity, but not CXC or C chemokines (alpha and gamma chemokines).

Belongs to the poxviridae chemokine-binding protein family.

26.366 kDa

MHVPASLQQSSSSSSSCTEEENKHHMGIDVIIKVTKQDQTPTNDKICQSVTEITESESDPDPEVESEDDSTSVEDVDPPTTYYSIIGGGLRMNFGFTKCPQIKSISESADGNTVNARLSSVSPGQGKDSPAITHEEALAMIKDCEVSIDIRCSEEEKDSDIKTHPVLGSNISHKKVSYEDIIGSTIVDTKCVKNLEFSVRIGDMCKESSELEVKDGFKYVDGSASEGATDDTSLIDSTKLKACV