Protein
Delta(1)-pyrroline-2-carboxylate reductase 1
Organism
Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)
Function
Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. May be involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline.
Similarity
Belongs to the LDH2/MDH2 oxidoreductase family.
Sequence
MSESLAEVVLSLDEVHALALRVLTHNGMSAAHAQAIANVITQGQRDECHSHGVYRLLVCVRSLKKGKVDPQAVPTLRRLSSSIVAVDAHRGFSLLSFETGLPVLVEMAKQHGIAAMAINHCYHFSALWPEVEAIAAEGLVGIAMNPSHSWVAPEGGREPVFGTNPIAFAWPRPDGVPFVFDFATSAIARGDIELHAKQGKAIPPHWAIDADGQPTTDPKAALQGAMRTFGGHKGSALAAMVELLGGALIGDMTSRESMAFDEGVGATPCHGELVIAFDPKVFLGDELDAGLARGERMFASITGQGARLPSQRRFDARARSIAHGVRIPKALYDEILTLLD