Protein
Envelope protein p54
Organism
African swine fever virus (strain Badajoz 1971 Vero-adapted)
Function
Envelope protein involved, through its interaction with host dynein, in the intracellular microtubule-dependent transport of viral capsid toward viral factories (PubMed:11559815). Seems to induce caspase-3 activation and apoptosis (PubMed:15225638). Plays a role in virion morphogenesis by recruiting and transforming the host ER membranes into the precursors of the viral envelope (PubMed:15047843).
Similarity
Belongs to the asfivirus envelope protein p54 family.
Sequence
MDSEFFQPVYPRHYGECLSPVTPPSFFSTHMYTILIAIVVLVIIIIVLIYLFSSRKKKAAAAIEEEDIQFINPYQDQQWAEVTPQPGTSKPAGATTASAGKPVTGRPATNRPATNKPVTDNPVTDRLVMATGGPAAAPAAASAHPTEPYTTVTTQNTASQTMSAIENLRQRNTYTHKDLENSL