Protein
Cyanuric acid amidohydrolase
Organism
Bradyrhizobium sp. (strain ORS 375)
Function
Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine. Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.
Similarity
Belongs to the cyclic amide hydrolase (CyAH) family.
Sequence
MPTTLRRAHVHRLPMRSPDDVAALEAAITQGTIDPAGIVAILGKTEGNGCVNDFTRAFAVRSLEALLGRHLATEAVRQIAMVMSGGTEGALSPHMIVFEAREVDEGHAPRAFAASLALGRARTPVLPSEHLGRMQQVAQVAAGVRAAMNDAGITDAGDVHYVQVKCPLLTMERIEAAEARGVRTAVRDTLKSMGFSRGASALGVAVALGELAMDELSDTEICTDYARYSERAATSGGVELLDHEIMVAGMSRDWTGPLAIDHGVMRDAIDIEPARAALARLGLDVPGQLPAAARGRIAAVLAKAEAAQSGKVRDVRHTMLDDSDVSSTRHARAFVGGALAGLFGFTDLFVSGGAEHQGPDGGGPVAIIVERT