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BOLA1

Gene
BOLA1
Protein
Protein BOLA1, chloroplastic
Organism
Arabidopsis thaliana
Length
160 amino acids
Function
May act either alone or in interaction with glutaredoxin as a redox-regulated transcriptional regulator, or as a factor regulating Fe-S cluster biogenesis (Probable). The glutaredoxin-BOLA1 heterodimers bind a labile, oxygen sensitive iron-sulfur cluster (PubMed:24714563).
Similarity
Belongs to the bolA/yrbA family.
Mass
17.672 kDa
Sequence
MFSSSIRLIVSGFHRTQPLKSPVNSPSVFISVPKFFNSESKSTGTGSRSVAMSSVEKTGSDSGAIENRASRMREKLQKELEPVELVIEDVSYQHAGHAGMKGRTDDETHFNVKIVSKGFEGMNLVKRHRLVYHLLREELDTGLHALSIVSKTPSESPSKD

Gene
BOLA1
Protein
BolA-like protein 1
Organism
Homo sapiens
Length
137 amino acids
Function
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5 (PubMed:27532772). May protect cells against oxidative stress (PubMed:22746225).
Similarity
Belongs to the BolA/IbaG family.
Mass
14.289 kDa
Sequence
MLSGRLVLGLVSMAGRVCLCQGSAGSGAIGPVEAAIRTKLEEALSPEVLELRNESGGHAVPPGSETHFRVAVVSSRFEGLSPLQRHRLVHAALAEELGGPVHALAIQARTPAQWRENSQLDTSPPCLGGNKKTLGTP

Gene
Bola1
Protein
BolA-like protein 1
Organism
Mus musculus
Length
137 amino acids
Function
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity).
Similarity
Belongs to the BolA/IbaG family.
Mass
14.379 kDa
Sequence
MLSARSAQCMVSMATRSCVSRGSAGSAAAGPVEAAIRAKLEQALSPEVLELRNESGGHAVPAGSETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGPVHALAIQAKTPAQWRENPQLDISPPCLGGSKKTRGTS

Gene
BOLA1
Protein
BolA-like protein 1
Organism
Pongo abelii
Length
137 amino acids
Function
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity).
Similarity
Belongs to the BolA/IbaG family.
Mass
14.187 kDa
Sequence
MLSGRLVPGLVSMAGRVCLCQGSAGSGAVGPVEAAIRTKLEQALSPEVLELRNESGGHAVPPGSETHFRVAVVSSRFEGLSPLQRHRLIHAALAEELAGPVHALAIQARTPAQWGENSQLDTSPPCLGGNKKTLGTP

Gene
BOLA1
Protein
BolA-like protein 1
Organism
Bos taurus
Length
135 amino acids
Function
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity).
Similarity
Belongs to the BolA/IbaG family.
Mass
14.355 kDa
Sequence
MLSGQLVVRLFSMASRVCMSRGSAGSGVIGPVEAAIRTKLEQALNPEVLELRNESGGHAVPPGSETHFRVAVVSSRFEGLSPLQRHRLVHAALSEELAGPVHALAIQARTPAQWKENPQLDTSPACLGGSKKSRN