BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)

Length

497 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

54.479 kDa

Sequence

MAATQKSLCAIPADPIEFPADANTLDYARSEDAKCPIRHMREHFIFPTRASLKKKALDGRLPAYPPNHAKPGETATAQNGTSNTNDDNVTPAVYFCGNSLGLQPKATRDHINAQLETWASIGVHGHFTSWDNSPLKSWQDMAADCAAQSASVVGASPDEIAIMNTLTANLHFMMASFYRPTEKRHKIISEWKPFPSDTYAIASQIQWHGFDTATSLVELHPDENYYISTEKILATIDEHAESTALLLLPGIQYWSGQLFDMPLITAHARAKGIVVGWDLAHAVGNVPLSLHDWDVDFAIWCTYKYLNAGPGAIAGAFVHERHGKVDSDGFKLRLSGWYGNNKATRFNMAKDFDPTPGAQGWVVSNPSGIDLASLGAALSVYNLTTPADLRKKSLWLTAYAEHLLNGILKDEAASSAGDGKKPAFRIITPSNKNERGAQLSVLLREGLLDVVGEKMEAAGVVCDRRKPDVMRVAPVPMYNSYEDVWRCVDALRKAVMS

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Coccidioides immitis (strain RS)

Length

478 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

53.331 kDa

Sequence

MVDSSKAPLPFRDSALSFKREYAESLDAQDPLREFRNQFIIPSKADLKRKSLAVAEGESPSSDCIYLCGNSLGLQPKNARMYIDRFLQTWATKAVLGHFTKLEDSPFPPYMDYDDVTSKLMAQVVGALPSEVAVMSTLTGNLHLLMASFYRPTKEKYKIILEGKAFPSDHYAVESQIRHHGFDPKDAMVLIEPKDLKEPVLPTERILKTIDEHASSTALILLPGIQYYSGQYLDIPTITAHAHSKGLLIGWDCAHAAGNVELKLHDWDVDFAAWCTYKYVNSGPGSMGALFVHEKHGQVNLENKEDPYRHRLTGWWGGDKSLRFLMDNNFVPRPGAAGFQLSNPSVLDMTAVLSSLDIFDKATMPALRKKSLELTAYLEHLLLNSPEGVRPSDDPFSIITPSDPEARGAQLSVLLKPGLLDSVFSHLVDNGVILDERKPDVIRVAPAPLYNTFTDVWDFVQIFFDACRKAAQEKDTTS

Protein

Kynureninase: BNA5

Gene

bna5

Protein

Kynureninase

Organism

Botryotinia fuckeliana (strain B05.10)

Length

475 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

52.872 kDa

Sequence

MGSIAKEEQPSTKVEKPTFSSKANTLEFAQSLDAKDHMRRFRDQYIIPSKANIKTKKLAKPGLSDEPSIYFCGNSLGLQPKCVQEYLQAHLDTWSSIAVHGHFRDLEDSPLTQWQLLAEHAAKQCAPIVGAKASEVAIMGTLTTNLHLLMASFYTPTPEKSKIIMEWKAFPSDHYAIESQIRGHGYNPEEAMVMIAPDEGSYEISTEKILRTIDEHASTTALLLLPGIQYYTGQLFDIKTITAYAQSKGLTVGWDLAHAAGNVPLQLHDWNVDFAVWCTYKYMNAGPGSIAGAYVHERHGEVDYSEGEEKPKYRHRLMGWYGGDQSCRFLMNNKFRPSPGASGYQVSNPSVVDLTSLCAALSIFNQTSMAEISQKTLHLTAYLEHLLLSTNSSDSPAFRIITPSDPSARGTQLSVLLKPGRLETLSDMLEEAGIVADKRKPDVIRVAPVPLYNTYEDVWNFVQIFNKALEKCEEA

Protein

Kynureninase: bna5

Gene

bna5

Protein

Kynureninase

Organism

Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)

Length

475 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

52.956 kDa

Sequence

MGSIAKEEQPSKVEKPTFSSKANTLEYAQSLDANDHMRRFRDQFIIPSKANIKATKLEKPGLSDESSIYFCGNSLGLQPKCVKEYLQAHLDTWSSIGVHGHFRDLEDSPLTQWQLLAEHASKQCAPIVGAKASEVAMMGTLTTNLHLLMASFYTPTPEKNKIIMEWKAFPSDHYAIESQIRGHGYNPQEAMVMIGPEEGSYEISTEKILRTIDEHASTTALVLLPGIQYYTGQLFDVKTITAYAQSKGLIVGWDLAHAAGNVPLQLHDWNVDFAVWCTYKYMNAGPGSIAGAFIHERHGEVDYSEGEEKPKYRHRLMGWYGGDQSCRFLMNNKFRPSPGASGYQVSNPSVVDLTSLCAALSIFNQTSMEEISQKTLHLTAYLEHLLLTSNPSNTNPAFRIITPSDPSARGTQLSVLLKPGRLETLSDMLEEAGIVADKRKPDVIRVAPVPLYNTYEDVWRFVQIFNAALEKCEEA

Protein

Kynureninase: bna5

Gene

BNA5

Protein

Kynureninase

Organism

Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)

Length

465 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

52.84 kDa

Sequence

MSLEKAQELDTKYPTYKDEFAVPTFKSLGIETSQFNENTDSIYLCGNSLGLMPKSTKQAINDELNAWIERGVESHFNHPGQSEGKTPWVDIDLPLVPLVAPIVGAKENEVAVMGSLTSNLNALLINFYKPKDKRTKILFEKQAFPSDYYAFLNLVKLHGYDESHLVQLKVLPGNTYLTTEQIKKAVDDNIDELAMVCFPGIQYYTGQFFKIEEITNYVKNKGKNEIVVGWDLAHAVGNVPLKLHDWNVDFAAWCSYKYLNSGPGGIAGIYVHEQYTKDNSKTSFSPRLAGWWGNNASDRFKMLEEFDPINSALSYRQSNPSVIDVVAVKSSLELFKKVGGVPKLRKKSIALTQFLQDLLVSSKYYFRSDNDTDRSKIGFTILTPLNQEERGAQLSVLFQPHYDDKQKNIMERVSGYLHNHAIICDERRPDVIRFAPLPLYNTFEETYYAAQRLFEALDKISSEEI

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)

Length

461 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

52.331 kDa

Sequence

MSSDKAKAFDAQFPTYKSEFQIPTFESLGIQNSKYSPETNSIYLCGNSLGLMPRNTTELINRELQAWSSRGVEAHFNHSHPQGTDWVDIDLPLLPLLAPLVGAKQNEVAVMGSLTSNLNALLIHFYKPKGKRTKILFEKQAFPSDYYAFLNIVQVFGYDASHLIQIEIPKGETYIKTETILDVFDKYEDEIAIVCLPGIQYYTGQFFDIAKITKHVKTSAPDVVVGWDLAHAVGNVPLSLHDWGVDFAAWCSYKYLNAGPGAIAGIFVNEKYTEQNKPENYKPRLAGWWGNNSSQRFQMLEKFDPIASALSYRQLNPSVLDCVALKSSLEIFNKVGGMLSLRDKSLAMTQFLQDILTKSNYYIEQGETDVNKFGFKIITPLDPNQRGCQLSLLFQPHRDEKKQNVMERVFEYLHQHAIICDERRPDVIRLAPLPLYNTFEETRIGATRLLEALEAIKDDYI

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876)

Length

461 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

52.384 kDa

Sequence

MSLAEAKKLDKKFPTFKNEFAIPTFGSLGIKNNKYESSTESIYLCGNSLGLMPKNTKKAINDELNAWVERGVESHFNHPDKSLTPWVDIDLPLLPLIAPIVGAKENEVAVMGSLTANLNALLIHFYKPEGKRTKILFEKQAFPSDYYAFLNIVKLFGYDEKHLIQLEVQPGETYIKTERIIKAIDENSDELALVCFPGIQYYTGQFFKIEEITKYAKEKSQQIKVGWDLAHAVGNVPLNLHDWGVDFAAWCSYKYLNSGPGAIGGIFVHEKYTIENKKSSFVPRLAGWWGNNSQERFKMLEEFDPINSALSYRQSNPSVLDVVAVKSSLEVYAKVGGVSKLREKSVALTQFLQDLLTNSKYYIPQSSTSNSKFGFKILTPLNPAERGCQLSIMFQPHFDEKDKNVMERVNAYLHDHAIICDERRPDVIRLAPLPLYNTFEETFIAVQRLFEALDNISKEYM

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)

Length

460 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

52.093 kDa

Sequence

MSIEQAKKLDECFPTYKEEFEIPTFKSLGIQNDEYEDSTDSIYLCGNSLGLMPKITRTAINDELNAWSERGVESHFRHPGEEKGLTSWVDIDLPLLPLIAPIVGGKENEVAVMGTLTSNLNAMLMSFYKPSGKKTKILFEKQAFPSDYYAFLNAAKIFGYNEDHLIQIEIKEGKTYIETEDIIETITNHQDELALVCFSGIQYYTGQFFNIGEITECAKSFGITVGWDLAHAVGNVPLQLHDWDVDFAVWCSYKYLNSGPGGIAGIFVHEKHTKDNSIEQFKPRLAGWWGNNASDRFKMLEVFDPIKSALSYRQSNPSVIDVVAVKSSLELFKKVGGISELRKKSVELTGFLQALLTSSKYYIKQEETTDRLGFKILSPLNKGDRGCQLSVLFQPHYEEYSKNIMERVNKYLSDHAIVCDERRPDVIRLAPLPLYNTFSETFIAVQRLIEAMDKIAANEI

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)

Length

455 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.982 kDa

Sequence

MGIPVNSENVNDETEGDVAGKEVYYLCGNSLGLMPKDTKETVTRELDAWRDRAVESHFKHPTDTSWVDIDLPVVPLLAPIVGGKNEEVAVMNTLTANLNSLLVSFYRPTKKRFKIVFEKKAFPSDYYAFYNQCRLHNFDPNECILQISARPNETFLRTEDILKVIEENNESIALVCLPGIQYYSGQLFEIERITKFAHQYPEIIVGWDLAHAVGNVPLKLHDWGVDFACWCSYKYLNSGPGSIGGLFIHEKWHHSALKFGDDVNHDEYRPRLAGWWGNNNEKRFQMLEKFEPIKGALGFRQSNPSVLDVVCLQSSLKIFQKYGGVENLRLKSLKLTKYLINQLQKSPYYHPKKQSSKEELGFRIITPIQNESQYGAQISIQLTPSRLTGKNKDTMEIVFEYMHRHGVVVDERKPNVIRISPVPLYNTFQDVFTTVAILNSALDSVKKSIKALKSN

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)

Length

453 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.17 kDa

Sequence

MSNDLPTKKDLVKWDQEDALNWTRGEYEIPNSKACGGEADGKAIYFCGNSLGLLNKKARQHIMEELDVWSTSSVTGHFNHPYQRPWKHVDEPLTPHLAKLVGAREEEVAHTSTLTSNMHNLFTSFYQPTEKRWKIVIEKGSFPSDWYAVHSHPRLHDKVLRPEQIDNAIIALVPREGEDTLRTEDILKVLDDNKDSIAIVWLPLVQYYTGQLFDISSISPKVHEIGALLGLDMAHGIGNVECKLNEWNVDFAVWCTYKYLNAGPAAIGGFYIRSGLEDGGRRLAGWWGNDARTRFHMSPNFQPTPGAKGYQHSCTPVFSSIPLLATLQLIEAVGFSNMVEKARRLTGTLEALLKASRYYVHPADPKGKIGFKIITPAAPYRGTQLSLVILPEEEHVMPKVFDRMLRKGLVGDERKPSVIRLSPVVLYNTFEEVGRAVEIVEEALEEEEEERKR

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)

Length

453 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.144 kDa

Sequence

MSNDLPTKKDLVKWDQEDALNWTRGEYEIPNSKACGGEADGKAIYFCGNSLGLLNKKARQHIMEELDVWSTSSVTGHFNHPYQRPWKHVDEPLTPHLAKLVGAREEEVAHTSTLTSNMHNLFTSFYQPTEKRWKIVIEKGSFPSDWYAVHSHPRLHDKVLRPEQIDNAIIALVPREGEDTLRTEDILKVLDDNKDSIAIVWLPLVQYYTGQLFDISSISPKVHEIGALLGLDMAHGIGNVECKLNEWNVDFAVWCTYKYLNAGPAAIGGFYIRSGLEDGGRRLAGWWGNDARTRFHMSPNFQPTPGAKGYQHSCTPVFSSIPLLATLQLIEAVGFSNMVEKARRLTGTLEALLKASRYHVHPADPKGKIGFKIITPAAPYRGTQLSLVILPEEEHVMPKVFDRMLRKGLVGDERKPSVIRLSPVVLYNTFEEVGRAVEIVEEALEEEEEERKR

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

453 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

51.032 kDa

Sequence

MEKALELDGEYPESLRDEFNIPTFKSMGLSSDDKPVTYLCGNSLGLMPKSTRNSINAELDAWSDCAVESHFKHPEEARGKVPWVSIDLPILPLLAPIVGAQENEVAVMNSLTANLNSLLITFYKPTEKRFKILFEKGSFPSDYYAFYNQCKIHGISEPENVFIQIEPREGETYIRTQDILDTIEVNQDELALVCLSGVQYYTGQYFDIGRITSFAHQFPDILVGWDLAHAVGNVPLQLHDWGVDFACWCSYKYLNAGPGGIGGLFVHSKHTKPDPAKESLPRLAGWWGNDPAKRFQMLEVFEPIPGALGFRQSNPSVIDTVALRSSLELFAKFNGINEVRKRSLLLTNYMTELLEASKYYKHPLRIEKLPCFFTILTPTSTDEEHGAQLSLYFDSDTGKEDIMPKVFQYLHDHGVIGDARRPNVIRLAPAPLYNTFSDVYIAVNALNEAMDKL

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)

Length

447 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

49.032 kDa

Sequence

MEKARALEEQWPGARDAFHVPSYASLGLGDQTAAVRYLCGHSLGCMPRKTRGSVEAELSAWSARAVEAHVRHPGGTEWVNTDLPLVPQMARMVGASQQEVAVMGSLTANLNALLVAFYRPRGRRTKILLEKQVFPSDFHAFWNQAALHGLDPAATLVQVAPRAGEHTLRTEDIVAAIETHRAELALVCLPGVQYYTGQLLDMASIVAAARREPSIVVGFDLAHAVGNVQLQLHEWGADFACWCSYKYLNAGPGGIAGLFVHERHHGGTLPRLAGWWGTNAATRFEMRQTYDPLPDALGFRQSNPSVLDVAALRASLEVFEDFGGMERVRARSLALTGYLYELLTQSVFYRPEVGADGVGFTILTPANPAERGAQLSLLFWPHSDDPDKNTMPRVFADLRQNGVLGDERHPDVIRLTPCALYNTFMEVFESVQLLNAALERLAPESAV

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)

Length

445 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

50.662 kDa

Sequence

MSAQLDKEYPTFRHLFEVPTLKSLNISSDTNESIYLCGNSLGLMPKSTRKAINDELDTWAQQGVEGHFSHPERTPWVDIDLPLLPLMAPIVGAKESEVAVMGSLTSNLNAMLMSFYKPKGKRTKILFEKHAFPSDYYAFLNIVQLFGYDESHLIQVAVQDGATYLRTEDIIFEIENNAEELALVCFPGIQYYTGQFFDIKSITKAAQDHGICVGWDLAHAVGNVPLNLHDWNVDFAVWCSYKYLNSGPGAMAGIFVHQRHTENNSKTSYNPRLAGWWGNNAQERFQMKEEFNPINSALSYRQSNPSVIDTVAVKASLKVFQEANGIQFLREKSIKMTQFLQDLLTQSQYYINQNEKPTKLGFQILTPLDPNQRGCQLSLLFHPHYDEKSKNIMEQVNKYLHNRGIVCDERRPDVIRVAPTPLYNTFAEIEYAVKSLNEALNQIEN

Protein

Kynureninase: BNA5

Gene

BNA5

Protein

Kynureninase

Organism

Yarrowia lipolytica (strain CLIB 122 / E 150)

Length

437 amino acids

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.

Similarity

Belongs to the kynureninase family.

Mass

48.411 kDa

Sequence

MPLNFRDRFNVPVLKNGEEVAYLVGNSLGLMPHKTRDYVNQEMDAWSQLGVKGHFVSGKEDLGQDVHQGPWYSCDEPLHGLVGPILGASEDEVAIMNTLTSNIHSLFSAFYKPTAKRSKILFEAKAFPSDTYAMEAQARLHNLDPSEALIKLAPKDGLHTLSDDDIIKVIEEQGDEIAVVFFSGIQFYTGQLFDIPRITAAAKAKGCVVGWDLAHAAGNVPLKLHDWNVDFAVFCTYKYMNSGPGGIGGLFVHDKYADDQRPRLAGWWGNNAETRFKMLDEFDPIRGARGYKQSNPSVLCVLALRASLELFKEAGGIEKLRERSIELTNRLLKGLLASPHYIAPENIEIFGNSGKAWFTIITPQAEHQRGAQLSLLFGPDGTMKKVFDYLDDHGVLGDERNPDVIRLAPAPLYNNERDVDLAIKLINDSINLINGSA

Protein

Kynureninase: BNA5