Protein
Probable inosine/xanthosine triphosphatase
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Function
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
Similarity
Belongs to the YjjX NTPase family.
Sequence
MWTIMIGSKNRAKVHALQEVVIRDKIIVRSEAVPSDVASQPFSDQETIQGAINRANHCLSFDGVDYGVGLEGGVVRSEYGLFLCNWGALVSQTGDQWVAGGARVPLPQEVAHELEGGKELGDIMESLTKNPDVRMTDGAIGYLTDGEISRKAMFQHVVHLLIGQARRDGHLLRTVTH