BEM3

GTPase-activating protein BEM3

1128 amino acids

GTPase-activating protein (GAP) for CDC42 and less efficiently for RHO1. Negative regulator of the pheromone-response pathway through the STE20 protein kinase.

124.913 kDa

MTDNLTTTHGGSTTLELLAQYNDHRSKKDKSIEHIEKGTCSGKERNPSYDEIFTENIKLKLQVQEYETEIESLEKVIDMLQKNREASLEVVLEQVQNDSRDSYVNDQSFVLPPRSAERKAHIKSLNLPIPTLSPPLQQGSDVALETSVTPTVPQIGVTSNTSISRKHLQNMILNDEIEANSSFSSPKIINRSVSSPTKIHSEQLASPAASVTYTTSRITIKSPNKGSKSPLQERLRSPQNPNRMTAVINNHLHSPLKASTSNNLDELTESKSQQLTNDAIQKNDRVYSSITSSAYTTGTPTSAAKSPSSLLEVKEGENKALGFSPASKEKLDDFTQLLDSSFGEEDLVNTDSKDPLSIKSTINESLPPPPAPPTFFSPTSSGNIKNSTPLSSHLASPVILNKKDDNFGAQSAKNLKKPVLTSSLPNLSTKLSTTSQNASLPPNPPVESSSKQKQLGETASIHSTNTLNTFSSTPQGSLKTLRRPHASSVSTVKSVAQSLKSDIPLFVQPEDFGTIQIEVLSTLYRDNEDDLSILIAIIDRKSGKEMFKFSKSIHKVRELDVYMKSHVPDLPLPTLPDRQLFQTLSPTKVDTRKNILNQYYTSIFSVPEFPKNVGLKIAQFISTDTVMTPPMMDDNVKDGSLLLRRPKTLTGNSTWRVRYGILRDDVLQLFDKNQLTETIKLRQSSIELIPNLPEDRFGTRNGFLITEHKKSGLSTSTKYYICTETSKERELWLSAFSDYIDPSQSLSLSSSRNANDTDSASHLSAGTHHSKFGNATISATDTPSYVTDLTQEYNNNNNISNSSNNIANSDGIDSNPSSHSNFLASSSGNAEEEKDSRRAKMRSLFPFKKLTGPASAMNHIGITISNDSDSPTSPDSIIKSPSKKLMEVSSSSNSSTGPHVSTAIFGSSLETCLRLSSHKYQNVYDLPSVVYRCLEYLYKNRGIQEEGIFRLSGSSTVIKTLQERFDKEYDVDLCRYNESIEAKDDEASPSLYIGVNTVSGLLKLYLRKLPHLLFGDEQFLSFKRVVDENHNNPVQISLGFKELIESGLVPHANLSLMYALFELLVRINENSKFNKMNLRNLCIVFSPTLNIPISMLQPFITDFACIFQGGEPVKEEEREKVDIHIPQV

BEM3

GTPase-activating protein BEM3

1013 amino acids

GTPase-activating protein (GAP) for CDC42 and less efficiently for RHO1. Negative regulator of the pheromone-response pathway through the STE20 protein kinase (By similarity).

111.66 kDa

MGDGSDAERSGGTSSSSALELLAQYEQHIMERGRTLEAIEGHGGERLGPTYEELVEENVQLRRELQGQREEIEHLRKTISLLASGRSGATVVEQQVRPEPSPSVRELALPPRSADRRKNTKNLSLAPVGHEVPSTDRLRVSPQEATSGAQQVPLLTSSKSAEILVSKSPDEDRHLMSPRKTISRSSSSYSNTLGSPATSVLYKNSRISITSPCKSNSTSKAASVLSLPENNTSTENAPHSPHRIDNELDLLTVEPQDGSRYDTERAGGPGPLSPESIVYSDSDLQEHQPSDLSSTTRTDLGKFRDMVDTTFNAEDNPTGSRDKETGTEMEIATLQNTPSRQHESSLVTSPQASRSSITTPVVDPTNTSEPSSLSAAKFGSMSTATSSNKRSKGMGTPSVEHSAKSYSQHSGSPHSNSHQSKKADIPLFVQPEELGTIRIEVISTLYHEPGNAASILFSVVDKKSSKEMFKFAKTFTRIAEFDTFIRNNMESLAVPPLPDKHMFASNVPVKVDSRREKLNDYFASLLYLSPLPFNPALKLAQFISTDPVMNPITGEFAKEGMLLVRKSKTLGSTTTWRIRYCTVEGSIMHLHDHMIDTDTIKLTHSTIELQANLPDDKYGTKNGFILNEHKKSGLSSSTKYYFCAETPKEREQWISVLTTLCDGPGGTAAIPSINSKSEASSLFEQTSISDSSYLGPIANLEAMDATSPTRPNDPNPVSLTSEEEKEVKRRRMKSFFPFKKLATTPTPYAAGNDNASIFSQDDDSPVNATNESGISRSLQSMNLQAQYNAVFGADLRSCLQLSSHPYQGKYEIPSVVFRTLEFLYKNRGIQEEGIFRLSGSSSLIKSLQEQFDKEYDVDLCNYNDKVSVTPGNENQGGLYVDVNTVSGLLKLYLRKLPHMIFGDAAYMDFKRIVERNGDDSKLIALEFRALVNSGRIAKEYVALMYALFELLVKITENSKYNKMNLRNLCIVFSPTLNIPVNILHPFITDFGCIFQDKAPMENGPPVNIHIPQI