Protein
Trans-3-hydroxy-L-proline dehydratase
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Function
Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which allows B.cereus to grow on t3LHyp as a sole carbon source. Displays no proline racemase activity.
Similarity
Belongs to the proline racemase family.
Sequence
MKVSKIYTTIDAHVAGEPLRIITGGVPEIKGETQLERRAYCMEHLDYLREILMYEPRGHHGMYGCIITPPASAHADFGVLFMHNEGWSTMCGHGIIAVITVGIETGMFEVTGEKQKFIIDSPAGEVIAYATYSGSEVESVSFENVPSFVYKKDVPIKIDSYEFQVDIAFGGAFYAVVDSKEFGLKVDFKDLSAIQMWGGKIKHYIESKMEVKHPLEEGLKGIYGVIFSDDPKEKDATLRNVTIFADGQVDRSPCGTGTSARIATLFAKDALQKGEIFVHECITDGKFEGEVLSVTAVHTYEAVVPKVTGNAFITGFHQFVVDPRDDLNRGFLLG