BCAR3

Breast cancer anti-estrogen resistance protein 3

826 amino acids

May act as an adapter protein and couple activated growth factor receptors to signaling molecules that regulate src kinase activity and promote cell migration.

92.765 kDa

MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLVERRADAYQDVSIHGTLPRKKKGPPPIRSCDNFSHVGTLPHSRSPRHHSPLIQDVIQEQPLQDWKGEAFTFRDQHLLDPTLEYVKFSKERHVMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLMQRDGDFLVRDSLSSPGDFVLTCQWKNLPQHFKIRRTVVRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPVNRTVPLRCLEERYGASSPDRAHEGSLTEGRPDAAKRLSLTVGGTQAREQGLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGGKLTPQSPSVGTSPCPNSPVFRTGSEPTLSPAVVRRVSSDARPGEALRGSDSQLCPKPPPKPCKAPLLKAPPSPSIWLNSEANYCELNPALAASYDGASRLPFCAQDSYVELLTAKQNGGLGTRNSDTSYLILDDDDRTRPWKPPPAPGDTVGEDQDTFVMPLLETTSSFKPNDFESKLLPPENKPLETSMLKRAKELFTNSDPKVIAQHLLSVDCKVARILEVSEEMRKNMGVNSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNKIIQVAVELKDSMGDLYSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRESTCVPPNNVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEIMLNHLATARLMAEAADSYRMNAERILAGFQPDEEMSEVFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQMEF

BCAR3

Breast cancer anti-estrogen resistance protein 3

825 amino acids

May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins.

92.566 kDa

MAAGKFASLPRNMPVNHQFPLASSMDLLSSRSPLAEHRPDAYQDVSIHGTLPRKKKGPPPIRSCDDFSHMGTLPHSKSPRQNSPVTQDGIQESPWQDRHGETFTFRDPHLLDPTVEYVKFSKERHIMDRTPEKLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLRCLEEHYGTSPGQAREGSLTKGRPDVAKRLSLTMGGVQAREQNLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPCPNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPSSPSAWLNSEANYCELNPAFATGCGRGAKLPSCAQGSHTELLTAKQNEAPGPRNSGVNYLILDDDDRERPWEPAAAQMEKGQWDKGEFVTPLLETVSSFRPNEFESKFLPPENKPLETAMLKRAKELFTNNDPKVIAQHVLSMDCRVARILGVSEEMRRNMGVSSGLELITLPHGHQLRLDIIERHNTMAIGIAVDILGCTGTLEDRAATLSKIIQVAVELKDSMGDLYSFSALMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKLLHEGRESTCVPPNNVSVPLLMPLVTLMERQAVTFEGTDMWEKNDQSCEIMLNHLATARFMAEAADSYRMNAERILAGFQPDEEMNEICKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL

BCAR3

Breast cancer anti-estrogen resistance protein 3

825 amino acids

May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins (By similarity).

92.592 kDa

MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLTEHRPDAYQDVSIHGTLPRKKKGPPPIRSCDDFSHMGTLPHSKSPQQNSPVTQDSIQESPWQDRHCETFTFRDPHLLDPTLEYVKFSKERHIMDRTPEKLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLRCLEERYGISPGQAREGSLTEGRPDVTKRLSLTMGGVQAREQNLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGCKLPPQSSGVDTSPCPNSPVFRTGSEPALSPAVVRRVSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKAPSSPSAWLNSEANYCELNPAFATGCGRGAKLPLCAQGSPTELLTAKQNGALGPRNSGINYLILDDDDRERPWEPAAAQTEKGQWDKGEFVAPLLETVSSFRPNDFKSKFLPPENKPLETAMLKRAKELFTNNDPKVIAQHILSMDCRVARILEVSEEMRRNMGVSSGLELITLPHGHQLRLDIIERHSTMAIGIAVYILGCTGTLEDRAATLSKVIQVAVELKDSMGDLYSFSALMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKILHEGRESTCVPPNNVSVPLLMPLVTLMERQAVTFEGTDMWEKNDQSCEIMLNHLATARLMAEATDSYRMNAERILAGFQPDEEMNEICKTEFQMRLLWGSKGAQVNQAERYEKFNQILTALSRKLEPPPVKQAEL

Bcar3

Breast cancer anti-estrogen resistance protein 3

820 amino acids

May act as an adapter protein and couple activated growth factor receptors to signaling molecules that regulate src kinase activity and promote cell migration.

92.263 kDa

MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLAERRTDAYQDVSIHGTLPRKKKGPPSIRSCDNAGHSKSPRQSSPLTQDIIQENPLQDRKGENFIFRDPYLLDPTLEYVKFSKERHIMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLWCLEERYGTSPGRGREGSLAEGRPDVVKRLSLTTGSSIQAREHSLPRGNLLRNKEKSGSQPACLDHVQDRKALTLKAHQSESHLPIGCKLPPQSPSMDTSPCPSSPVFRTGSEPTLSPALVRRFSSDARTGEALRGSDSQLCPKPPPKPCKVPFLKTPPSPSPWLTSEANYCELNPAFAVGCDRGAKLPMQAHDSHEMLLTAKQNGPSGPRNSGINYMILDGDDQARHWDPLAVQTDEGQEDKTKFVPPLMETVSSFRPNDFESKLLPPENKPLETAMLKHAKELFTNHDARVIAQHMLSVDCKVARILEVSEDRKRSMGVSSGLELITLPHGRQLRLDIIERHNTMAIGIAVDILGCTGTLENRAGTLNKIIQVAVELKDAMGDLYAFSAIMKALEMPQITRLEKTWTALRHHYTQTAILYEKQLKPFSKILHEGRESTYVPASNVSVPLLMPLVTLMERQAVTFEGTDMWENNDESCEILLNHLATARFMAEASESYRMNAERILADFQPDEEMTEILRTEFQMRLLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL

bcar3

Breast cancer anti-estrogen resistance protein 3 homolog

806 amino acids

May act as an adapter protein.

92.238 kDa

MAAGKFASYHRNVQMNHPLVSSMDLLGSKSALGERRSDAFKNVCIHGTLPRKKKERVPIRSSDMFCHMGTLPHTKSHRLPNPLMQDIKEDYPFQERRTGIFNMREHYLDPAMEYVKFSKDRYIMDGGTPDKLKKELEEELKLNSEDLRSHAWYHGRIPRQVSESLVKRDGDFLIRDSLSSPGNLVLTCQWKNLSQHFKINKVVIRLNEAYCRIQYQLEHESFDSIPALVRFYVGNRKAVSQQSGAIIFQPINRTVPLRCIEEKYGTSPVRRLELGIMEVKSEPTKRLSLNFGQGISQEQSLVRGNLLRNKEKSGSQPACLDNMREKRRPLKAHQSESYLPLGSRQPCLSQGMDMKTSPKPHVFRTGSEPTLSPTEIRRFNHEVHPVEALRGSDSQLCPRPPPKPTKAPSIKQSQSPLVWQSSEANYCEFHPTPPEDCAWSDSHSSHNSYIEDQRTDEIETLSFSNSELSFPALDDSISQCSATDFCGNVEDDEFIRPVYETVSSFCPNDFQSVLLTAENKPLETSLLRRAKELFTNNDPRTIAKHILRMDCKVARILDVTPEVERMMGVSSGLELIILPYGHQLRLDLMERHSTMAIGIAVDILGCTGNLEERVATLHKIIQLAVEVKTLGDYFAFSAIMKALDMPQITRLEQTWTMLRHQYTQTAITYEKQLKPFSKYLHEGEALDAQEDVTVPLVMPLVTLLERQSVLFEGMDFWENNDRGCEILFNHLQTARQVAHNATVYKKNAQRILEGFKPDELMSEIFKTEFQMRLLWGSKGALLKQSERYHKFGQILTALSRKLEPPS