Function
B-H1 and B-H2 are regulated by members of the wg signaling pathway; wg and dpp. B-H1 and B-H2 are coexpressed and functionally required in R1 and R6 receptor cells and primary pigment cells for normal eye development. Coexpression is also required for the fate determination of external sensory organs, formation of notal microchaetae, formation of presutural macrochaetae, antennal development and for distal leg morphogenesis; segmentation and specification of tarsal segments 3-5.
Sequence
MKDSMSILTQTPSEPNAAHPQLHHHLSTLQQQHHQHHLHYGLQPPAVAHSIHSTTTMSSGGSTTTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGATPHTNIDIYYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPHPVAPPPSVGGGSPPSGLVKPIPAHSASASPPPRPPSTPSPTLNPGSPPGRSVDSCSQSDDEDQIQV