Protein
Deoxyhypusine hydroxylase
Organism
Arabidopsis thaliana
Function
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
Similarity
Belongs to the deoxyhypusine hydroxylase family.
Sequence
MESNGSVSSMVNLEKFLCERLVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAHEAAFALGQMQDAEAIPALESVLNDMSLHPIVRHEAAEALGAIGLAGNVNILKKSLSSDPAQEVRETCELALKRIEDMSNVDAENQSSTTEKSPFMSVDPAGPAASFSSVHQLRQVLLDETKGMYERYAALFALRNHGGEEAVSAIVDSLSASSALLRHEVAYVLGQLQSKTALATLSKVLRDVNEHPMVRHEAAEALGSIADEQSIALLEEFSKDPEPIVAQSCEVALSMLEFENSGKSFEFFFTQDPLVH