Protein
Transmembrane emp24 domain-containing protein p24delta8
Organism
Arabidopsis thaliana
Function
Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side (By similarity). On Golgi membranes, acts as primary receptor for ARF1-GDP which is involved in COPI-vesicle formation.
Similarity
Belongs to the EMP24/GP25L family.
Sequence
MDLCRSSILLLIIALLSPRTLSMRYELKSSKTKCIGEEIHENAMSIGKYFIVNPNEDNHPLPDSHKIIVKVMPPQGKNLHEADKVEAGQFSFTAYENGSYVACITAIDYKPETTLTIDFDWKTGVHSKEWTNVAKKSQVDMMEYQVKTLMDTVISIHEEMYYLREREEEMQELNRSTNSKMAWLSFGSLVVCLSVAGLQFWHLKTFFEKKKLI