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Ass1

Gene
ASS1
Protein
Argininosuccinate synthase
Organism
Gallus gallus
Length
416 amino acids
Function
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
Similarity
Belongs to the argininosuccinate synthase family.
Mass
46.904 kDa
Sequence
MAEPRDTVVLAYSGGLDTSCILVWLKEQGYTVIAFLANIGQTEDFDAAQKKALALGAKKVYIQDVCREFVEDFIWPAVRANALYEDRYMLGSALARPCIARHLVLIAQEEGARYIAHGATGKGNDQVRFELGCYALCPSIKVIAPWRMPEFYQRFPGRRELMEYAQKHGIPVPVTPKAPWSMDENLMHISYEAGILENPKNRAPLDLYTKTCNPTTSPDVPDELEIEFEKGVPVKVTNTRNGVTHRSALELFVYLNDIASKHGVGRVDIVENRFVGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLSLKFSELVYNGFWYSPECEFLKHCIARSQQAVAGTVHVSVFKGQVYVLGRESPHSLYNEELVSMDVQGDYEPADATGFININALRLKEYHRLQSKVSTKQDE

Gene
Ass1
Protein
Argininosuccinate synthase
Organism
Mus musculus
Length
412 amino acids
Function
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
Similarity
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
Mass
46.584 kDa
Sequence
MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSKEFVEEFIWPAVQSSALYEDRYLLGTSLARPCIARRQVEIAQREGAKYVSHGATGKGNDQVRFELTCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKSPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNSPDVLEIEFKKGVPVKVTNIKDGTTRTTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIQKSQERVEGKVQVSVFKGQVYILGRESPLSLYNEELVSMNVQGDYEPIDATGFININSLRLKEYHRLQSKVTAK

Gene
Ass1
Protein
Argininosuccinate synthase
Organism
Rattus norvegicus
Length
412 amino acids
Function
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals (Probable). Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues (Probable). Indirectly, may be involved in the control of blood pressure (PubMed:19491403).
Similarity
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
Mass
46.496 kDa
Sequence
MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSKEFVEEFIWPAVQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELTCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKSPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDVLEIEFKKGVPVKVTNVKDGTTHSTSLDLFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIDKSQERVEGKVQVSVFKGQVYILGRESPLSLYNEELVSMNVQGDYEPIDATGFININSLRLKEYHRLQSKVTAK

Gene
ASS1
Protein
Argininosuccinate synthase
Organism
Bos taurus
Length
412 amino acids
Function
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
Similarity
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
Mass
46.417 kDa
Sequence
MSGKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVFIEDISKEFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQIRFELTCYSLAPQIKVIAPWRMPEFYNRFQGRNDLMEYAKQHGIPVPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNSPDMLEIEFKKGVPVKVTNVGDGTTHSTALELFLYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVFKGQVYILGRESPLSLYNEELVSMNVQGDYEPVDATGFININSLRLKEYHRLQNKVTAK

Gene
ASS1
Protein
Argininosuccinate synthase
Organism
Homo sapiens
Length
412 amino acids
Function
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
Similarity
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
Mass
46.53 kDa
Sequence
MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKDGTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK

Gene
ass1
Protein
Argininosuccinate synthase
Organism
Xenopus tropicalis
Length
412 amino acids
Function
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
Similarity
Belongs to the argininosuccinate synthase family.
Mass
46.851 kDa
Sequence
MSQSKGMVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQNEDFEAARKKAVNLGAKKVYIEDMRQQFVEEYIWPAVQANAIYEDRYLLGTSLARPCIAKKQVEIAKKEAAEYVSHGATGKGNDQIRFELTCYALYPEVKIIAPWRMPEFYNRFRGRSDLMEYAKKHNIPVPVTPKDPWSMDENIMHISYEGGILENPKNHAPPGLYLKTKNPATSPNEPDILEIEFKKGVPVKVTNTKEKTQHSSALGLFCYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYQAHLDVEAFTMDREVRKIKQHLSQRFAEQIYNGFWYSPECEFVRSCITKSQEMVEGKVLVSVLKGQVYVLGREAPHSLYNEELVSMDVQGDYDPADACGFIRINALRLKEFHRLQKSKKN

Gene
ass1
Protein
Argininosuccinate synthase
Organism
Xenopus laevis
Length
411 amino acids
Function
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
Similarity
Belongs to the argininosuccinate synthase family.
Mass
46.75 kDa
Sequence
MSQSKGTVVLAYSGGLDTSCILVWLKEQGFDVIAYLANIGQNEDFEEARKKAVNLGAKKVYIEDIRQQFVEEYIWPAVQANAIYEDRYLLGTSLARPCIAKKQVEIAKKEAAEYVSHGATGKGNDQIRFELTCYSLYPEVKIIAPWRMPEFYNRFRGRSDLMEYAKKHNISVPVTPKSPWSMDENLMHISYEGGILENPKNHAPPGLYLKTKDPATSPDEPDILEIEFKKGVPVKVTNTKNKTQHSSSLALFCYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYQAHLDIEAFTMDREMRKIKQQLSQRFAEQIYNGFWYSPECEFVRSCISKSQEMVEGKVLVSVLKGQVYVLGREAPHSLYNEELVSMDVQGDYDPADACGFIKINAVRLKEYHRLQKNKK