Protein
Adenylosuccinate synthetase
Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Function
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
Similarity
Belongs to the adenylosuccinate synthetase family.
Sequence
MGVTIVLGSQWGDEGKGKITDMLAQQATLCCRAAGGHNAGHTIVHGDKTYDFHILPSGLVSPSCVNLIGAGTVVHVPSFFKELASLEDKGLEGAGKRIFISDRAHVCFDLHSVVDGLEEAKLGGRKVGTTGKGIGPCYSDKAARRGVRVGEILDEALFERKLRSLDAGYRARFGELEYNVEEELARFKEYRKRLGPYIVDQLAFLQKYKDAPNTLVEGANALMLDLDHGTYPFVTSSSTGLGGAVQALSLNPTSISSIIGVVKAYTTRVGSGPFPSEQLNDAGDKLQGVGKEFGVTTGRRRRCGWFDMVLCRYSQAINHYTALNLTKLDVLDDFDEIKVGVAYILPDGTRTENTMPADPEVLEKVQVEYVTLPGWKSNTMGVKKYEDLPANARAYIEYIERGLGGVPVKWIGTGPARDHMICRE