Organism
Streptomyces galilaeus
Function
Involved in the biosynthesis of the anthracycline antitumor agent aclacinomycin A. AknT is required for the glycosylation of aklavinone aglycone by AknS to yield aclacinomycin T (rhodosaminyl-aklavinone).
Similarity
Belongs to the cytochrome P450 family.
Sequence
MQTQNAPETAENQQTDSELGRHLLTARGFHWIYGTSGDPYALTLRAESDDPALLTRRIREAGTPLWQSTTGAWVTGRHGVAAEALADPRLALRHADLPGPQRHVFSDAWSNPQLCHIIPLDRAFLHASDADHTRWARSASAVLGSAGGAPAEGVREHAGRVHREAADRTGDSFDLMADYSRPVATEAAAELLGVPAAQRERFAATCLALGVALDAALCPQPLAVTRRLTEAVEDVRALVGDLVEARRTQPGDDLLSAVLHAGSSAASAGQDALAVGVLTAVVGVEVTAGLINNTLESLLTRPVQWARLGENPELAAGAVEEALRFAPPVRLESRIAAEDLTLGGQDLPAGAQVVVHVGAANRDPEAFLAPDHFDLDRPAGQGQLSLSGPHTALFGAFARLQAETAVRTLRERRPVLAPAGAVLRRMRSPVLGAVLRFPLTTSA