ADGRV1

Adhesion G-protein coupled receptor V1

6306 amino acids

Cleaved ADGRV1 beta-subunit couples with G-alpha(i)-proteins, GNAI1/2/3, and constitutively inhibits adenylate cyclase (AC) activity with a stronger effect than full ADGRV1.

Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.

693.069 kDa

MSVFLGPGMPSASLLVNLLSALLILFVFGETEIRFTGQTEFVVNETSTTVIRLIIERIGEPANVTAIVSLYGEDAGDFFDTYAAAFIPAGETNRTVYIAVCDDDLPEPDETFIFHLTLQKPSANVKLGWPRTVTVTILSNDNAFGIISFNMLPSIAVSEPKGRNESMPLTLIREKGTYGMVMVTFEVEGGPNPPDEDLSPVKGNITFPPGRATVIYNLTVLDDEVPENDEIFLIQLKSVEGGAEINTSRNSIEIIIKKNDSPVRFLQSIYLVPEEDHILIIPVVRGKDNNGNLIGSDEYEVSISYAVTTGNSTAHAQQNLDFIDLQPNTTVVFPPFIHESHLKFQIVDDTIPEIAESFHIMLLKDTLQGDAVLISPSVVQVTIKPNDKPYGVLSFNSVLFERTVIIDEDRISRYEEITVVRNGGTHGNVSANWVLTRNSTDPSPVTADIRPSSGVLHFAQGQMLATIPLTVVDDDLPEEAEAYLLQILPHTIRGGAEVSEPAELLFYIQDSDDVYGLITFFPMENQKIESSPGERYLSLSFTRLGGTKGDVRLLYSVLYIPAGAVDPLQAKEGILNISRRNDLIFPEQKTQVTTKLPIRNDAFLQNGAHFLVQLETVELLNIIPLIPPISPRFGEICNISLLVTPAIANGEIGFLSNLPIILHEPEDFAAEVVYIPLHRDGTDGQATVYWSLKPSGFNSKAVTPDDIGPFNGSVLFLSGQSDTTINITIKGDDIPEMNETVTLSLDRVNVENQVLKSGYTSRDLIILENDDPGGVFEFSPASRGPYVIKEGESVELHIIRSRGSLVKQFLHYRVEPRDSNEFYGNTGVLEFKPGEREIVITLLARLDGIPELDEHYWVVLSSHGERESKLGSATIVNITILKNDDPHGIIEFVSDGLIVMINESKGDAIYSAVYDVVRNRGNFGDVSVSWVVSPDFTQDVFPVQGTVVFGDQEFSKNITIYSLPDEIPEEMEEFTVILLNGTGGAKVGNRTTATLRIRRNDDPIYFAEPRVVRVQEGETANFTVLRNGSVDVTCMVQYATKDGKATARERDFIPVEKGETLIFEVGSRQQSISIFVNEDGIPETDEPFYIILLNSTGDTVVYQYGVATVIIEANDDPNGIFSLEPIDKAVEEGKTNAFWILRHRGYFGSVSVSWQLFQNDSALQPGQEFYETSGTVNFMDGEEAKPIILHAFPDKIPEFNEFYFLKLVNISGGSPGPGGQLAETNLQVTVMVPFNDDPFGVFILDPECLEREVAEDVLSEDDMSYITNFTILRQQGVFGDVQLGWEILSSEFPAGLPPMIDFLLVGIFPTTVHLQQHMRRHHSGTDALYFTGLEGAFGTVNPKYHPSRNNTIANFTFSAWVMPNANTNGFIIAKDDGNGSIYYGVKIQTNESHVTLSLHYKTLGSNATYIAKTTVMKYLEESVWLHLLIILEDGIIEFYLDGNAMPRGIKSLKGEAITDGPGILRIGAGINGNDRFTGLMQDVRSYERKLTLEEIYELHAMPAKSDLHPISGYLEFRQGETNKSFIISARDDNDEEGEELFILKLVSVYGGARISEENTTARLTIQKSDNANGLFGFTGACIPEIAEEGSTISCVVERTRGALDYVHVFYTISQIETDGINYLVDDFANASGTITFLPWQRSEVLNIYVLDDDIPELNEYFRVTLVSAIPGDGKLGSTPTSGASIDPEKETTDITIKASDHPYGLLQFSTGLPPQPKDAMTLPASSVPHITVEEEDGEIRLLVIRAQGLLGRVTAEFRTVSLTAFSPEDYQNVAGTLEFQPGERYKYIFINITDNSIPELEKSFKVELLNLEGGVAELFRVDGSGSGDGDMEFFLPTIHKRASLGVASQILVTIAASDHAHGVFEFSPESLFVSGTEPEDGYSTVTLNVIRHHGTLSPVTLHWNIDSDPDGDLAFTSGNITFEIGQTSANITVEILPDEDPELDKAFSVSVLSVSSGSLGAHINATLTVLASDDPYGIFIFSEKNRPVKVEEATQNITLSIIRLKGLMGKVLVSYATLDDMEKPPYFPPNLARATQGRDYIPASGFALFGANQSEATIAISILDDDEPERSESVFIELLNSTLVAKVQSRSIPNSPRLGPKVETIAQLIIIANDDAFGTLQLSAPIVRVAENHVGPIINVTRTGGAFADVSVKFKAVPITAIAGEDYSIASSDVVLLEGETSKAVPIYVINDIYPELEESFLVQLMNETTGGARLGALTEAVIIIEASDDPYGLFGFQITKLIVEEPEFNSVKVNLPIIRNSGTLGNVTVQWVATINGQLATGDLRVVSGNVTFAPGETIQTLLLEVLADDVPEIEEVIQVQLTDASGGGTIGLDRIANIIIPANDDPYGTVAFAQMVYRVQEPLERSSCANITVRRSGGHFGRLLLFYSTSDIDVVALAMEEGQDLLSYYESPIQGVPDPLWRTWMNVSAVGEPLYTCATLCLKEQACSAFSFFSASEGPQCFWMTSWISPAVNNSDFWTYRKNMTRVASLFSGQAVAGSDYEPVTRQWAIMQEGDEFANLTVSILPDDFPEMDESFLISLLEVHLMNISASLKNQPTIGQPNISTVVIALNGDAFGVFVIYNISPNTSEDGLFVEVQEQPQTLVELMIHRTGGSLGQVAVEWRVVGGTATEGLDFIGAGEILTFAEGETKKTVILTILDDSEPEDDESIIVSLVYTEGGSRILPSSDTVRVNILANDNVAGIVSFQTASRSVIGHEGEILQFHVIRTFPGRGNVTVNWKIIGQNLELNFANFSGQLFFPEGSLNTTLFVHLLDDNIPEEKEVYQVILYDVRTQGVPPAGIALLDAQGYAAVLTVEASDEPHGVLNFALSSRFVLLQEANITIQLFINREFGSLGAINVTYTTVPGMLSLKNQTVGNLAEPEVDFVPIIGFLILEEGETAAAINITILEDDVPELEEYFLVNLTYVGLTMAASTSFPPRLDSEGLTAQVIIDANDGARGVIEWQQSRFEVNETHGSLTLVAQRSREPLGHVSLFVYAQNLEAQVGLDYIFTPMILHFADGERYKNVNIMILDDDIPEGDEKFQLILTNPSPGLELGKNTIALIIVLANDDGPGVLSFNNSEHFFLREPTALYVQESVAVLYIVREPAQGLFGTVTVQFIVTEVNSSNESKDLTPSKGYIVLEEGVRFKALQISAILDTEPEMDEYFVCTLFNPTGGARLGVHVQTLITVLQNQAPLGLFSISAVENRATSIDIEEANRTVYLNVSRTNGIDLAVSVQWETVSETAFGMRGMDVVFSVFQSFLDESASGWCFFTLENLIYGIMLRKSSVTVYRWQGIFIPVEDLNIENPKTCEAFNIGFSPYFVITHEERNEEKPSLNSVFTFTSGFKLFLVQTIIILESSQVRYFTSDSQDYLIIASQRDDSELTQVFRWNGGSFVLHQKLPVRGVLTVALFNKGGSVFLAISQANARLNSLLFRWSGSGFINFQEVPVSGTTEVEALSSANDIYLIFAENVFLGDQNSIDIFIWEMGQSSFRYFQSVDFAAVNRIHSFTPASGIAHILLIGQDMSALYCWNSERNQFSFVLEVPSAYDVASVTVKSLNSSKNLIALVGAHSHIYELAYISSHSDFIPSSGELIFEPGEREATIAVNILDDTVPEKEESFKVQLKNPKGGAEIGINDSVTITILSNDDAYGIVAFAQNSLYKQVEEMEQDSLVTLNVERLKGTYGRITIAWEADGSISDIFPTSGVILFTEGQVLSTITLTILADNIPELSEVVIVTLTRITTEGVEDSYKGATIDQDRSKSVITTLPNDSPFGLVGWRAASVFIRVAEPKENTTTLQLQIARDKGLLGDIAIHLRAQPNFLLHVDNQATENEDYVLQETIIIMKENIKEAHAEVSILPDDLPELEEGFIVTITEVNLVNSDFSTGQPSVRRPGMEIAEIMIEENDDPRGIFMFHVTRGAGEVITAYEVPPPLNVLQVPVVRLAGSFGAVNVYWKASPDSAGLEDFKPSHGILEFADKQVTAMIEITIIDDAEFELTETFNISLISVAGGGRLGDDVVVTVVIPQNDSPFGVFGFEEKTVMIDESLSSDDPDSYVTLTVVRSPGGKGTVRLEWTIDEKAKHNLSPLNGTLHFDETESQKTIVLHTLQDTVLEEDRRFTIQLISIDEVEISPVKGSASIIIRGDKRASGEVGIAPSSRHILIGEPSAKYNGTAIISLVRGPGILGEVTVFWRIFPPSVGEFAETSGKLTMRDEQSAVIVVIQALNDDIPEEKSFYEFQLTAVSEGGVLSESSSTANITVVASDSPYGRFAFSHEQLRVSEAQRVNITIIRSSGDFGHVRLWYKTMSGTAEAGLDFVPAAGELLFEAGEMRKSLHVEILDDDYPEGPEEFSLTITKVELQGRGYDFTIQENGLQIDQPPEIGNISIVRIIIMKNDNAEGIIEFDPKYTAFEVEEDVGLIMIPVVRLHGTYGYVTADFISQSSSASPGGVDYILHGSTVTFQHGQNLSFINISIIDDNESEFEEPIEILLTGATGGAVLGRHLVSRIIIAKSDSPFGVIRFLNQSKISIANPNSTMILSLVLERTGGLLGEIQVNWETVGPNSQEALLPQNRDIADPVSGLFYFGEGEGGVRTIILTIYPHEEIEVEETFIIKLHLVKGEAKLDSRAKDVTLTIQEFGDPNGVVQFAPETLSKKTYSEPLALEGPLLITFFVRRVKGTFGEIMVYWELSSEFDITEDFLSTSGFFTIADGESEASFDVHLLPDEVPEIEEDYVIQLVSVEGGAELDLEKSITWFSVYANDDPHGVFALYSDRQSILIGQNLIRSIQINITRLAGTFGDVAVGLRISSDHKEQPIVTENAERQLVVKDGATYKVDVVPIKNQVFLSLGSNFTLQLVTVMLVGGRFYGMPTILQEAKSAVLPVSEKAANSQVGFESTAFQLMNITAGTSHVMISRRGTYGALSVAWTTGYAPGLEIPEFIVVGNMTPTLGSLSFSHGEQRKGVFLWTFPSPGWPEAFVLHLSGVQSSAPGGAQLRSGFIVAEIEPMGVFQFSTSSRNIIVSEDTQMIRLHVQRLFGFHSDLIKVSYQTTAGSAKPLEDFEPVQNGELFFQKFQTEVDFEITIINDQLSEIEEFFYINLTSVEIRGLQKFDVNWSPRLNLDFSVAVITILDNDDLAGMDISFPETTVAVAVDTTLIPVETESTTYLSTSKTTTILQPTNVVAIVTEATGVSAIPEKLVTLHGTPAVSEKPDVATVTANVSIHGTFSLGPSIVYIEEEMKNGTFNTAEVLIRRTGGFTGNVSITVKTFGERCAQMEPNALPFRGIYGISNLTWAVEEEDFEEQTLTLIFLDGERERKVSVQILDDDEPEGQEFFYVFLTNPQGGAQIVEEKDDTGFAAFAMVIITGSDLHNGIIGFSEESQSGLELREGAVMRRLHLIVTRQPNRAFEDVKVFWRVTLNKTVVVLQKDGVNLVEELQSVSGTTTCTMGQTKCFISIELKPEKVPQVEVYFFVELYEATAGAAINNSARFAQIKILESDESQSLVYFSVGSRLAVAHKKATLISLQVARDSGTGLMMSVNFSTQELRSAETIGRTIISPAISGKDFVITEGTLVFEPGQRSTVLDVILTPETGSLNSFPKRFQIVLFDPKGGARIDKVYGTANITLVSDADSQAIWGLADQLHQPVNDDILNRVLHTISMKVATENTDEQLSAMMHLIEKITTEGKIQAFSVASRTLFYEILCSLINPKRKDTRGFSHFAEVTENFAFSLLTNVTCGSPGEKSKTILDSCPYLSILALHWYPQQINGHKFEGKEGDYIRIPERLLDVQDAEIMAGKSTCKLVQFTEYSSQQWFISGNNLPTLKNKVLSLSVKGQSSQLLTNDNEVLYRIYAAEPRIIPQTSLCLLWNQAAASWLSDSQFCKVVEETADYVECACSHMSVYAVYARTDNLSSYNEAFFTSGFICISGLCLAVLSHIFCARYSMFAAKLLTHMMAASLGTQILFLASAYASPQLAEESCSAMAAVTHYLYLCQFSWMLIQSVNFWYVLVMNDEHTERRYLLFFLLSWGLPAFVVILLIVILKGIYHQSMSQIYGLIHGDLCFIPNVYAALFTAALVPLTCLVVVFVVFIHAYQVKPQWKAYDDVFRGRTNAAEIPLILYLFALISVTWLWGGLHMAYRHFWMLVLFVIFNSLQGLYVFMVYFILHNQMCCPMKASYTVEMNGHPGPSTAFFTPGSGMPPAGGEISKSTQNLIGAMEEVPPDWERASFQQGSQASPDLKPSPQNGATFPSSGGYGQGSLIADEESQEFDDLIFALKTGAGLSVSDNESGQGSQEGGTLTDSQIVELRRIPIADTHL

Adgrv1

Adhesion G-protein coupled receptor V1

6298 amino acids

Cleaved ADGRV1 beta-subunit couples with G-alpha(i)-proteins, GNAI1/2/3, and constitutively inhibits adenylate cyclase (AC) activity with a stronger effect than full ADGRV1.

Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.

687.458 kDa

MSVTSEPGMISSFLLVYLSTLFISFVFGEAEIRFTGQTEFFVNETSTTVIRLVIERIGEPANVTAIVSLSGEDTGDFFDTYAAAFIPARGTNRTVYIAVCDDDLPEPDETFTFHLTLQKPSANVKLGWPRAASVTILSNDNAFGIISFSTPSSISVIEPRSRNASVPLTLIREKGTYGMVTVTFDVSGGPNPPEEDLNPVRGNITFPPGRATVIYNVTVLDDEVPENDELFLIQLRSVEGGAEINASRSSVEIIVKKNDSPVNFMQSVYVVPEDDHVLTIPVLRGKDSDGNLIGSDETQVSIRYKVMTWDSTAHAQQNVDFIDLQPDTTLVFPPFVHESHLKFQIIDDLIPEIAESFHIMLLKNTLQGDAVLMGPSTVQVTIKPNDKPYGVLSFNSILFERPVIIDEDTASSSRFEEIAVVRNGGTHGNVSVSWVLTRNSSDPSPVTADITPASGTLQFAQGQMLAPISLVVFDDDLPEEAEAYLLTILPHTIQGGAEVSEPAQLLFYIQDSDNVYGEIAFFPGESQKIESSPSERSLSLSLARRGGSKGDVRVIYSALYIPAGAMDPLRAKDGILNTSRRSSLLFPEQNQQVSIKLPIRNDAFLQNGAHFLVQLEAVVLVNIFPPIPPVSPRFGEIRNISLLVTPAIANGEIGFLSNLPIILHEPKDSSAEVVSIPLHRDGTDGQATVYWSLRPSGFNSKAVTLDDAGPFNGSVVFLSGQNETSINITVKGDDIPELNETVTLSLDRVSVDSDVLKSGYTSRDLIILENDDPGGIFEFSYDSRGPYVIKEGDAVELRITRSRGSLVKQFLRFHVEPRESNEFYGNMGVLEFTPGEREVVITLLTRLDGTPELDEHFWVILSSHGERESKLGRATLVNITILKNDYPHGIIEFVSDGLSASIKESKGEDIYHAVYGVIRTRGNFGAVNVSWMVSPDFTQDVFPVQGTVCFGDQEFFKNITVYSLVDEIPEEMEEFTIILLNATGGAQTGIRTTASLRILRNDDPVYFAEPCVLRVQEGETANFTVLRNGSVDGACTVQYATVDGKASGEEGDFAPVEKGETLVFEVGSREQSISVHVKDDGIPETDEPFYIVLFNSTGDTVVYEYGVATVIIEANDDPNGVFSLEPIDKAVEEGKTNAFWILRHRGHFGNVSVAWQLFQNASLQPGQEFYETSGTVNFTDGEETKPVILRAFPDRIPEFNEFYILRLVNISGPGGQLAETNFQVTVMIPFNDDPFGIFILDPECLEREVAEDVLSEDDMSYITSFTILRQQGVFGDVRVGWEVLSREFTAGLPPMIDFILLGSFPSTVPLQPHMRRHHSGTDVLYFSGLEGAFGTVDPKYQPFRNNTIANFTFSAWVMPNANTNGFLIAKDDSHGSIYYGVKIQTNETHVTLSLHYKTFGSNVTYIAKSTVMKYLEEGVWLHVLIILDDGIIEFYLDGKAMPRGIKSLKGEAITDGPGILRIGAGMDGGARFTGWMQDVRTYERKLTPEEIYELHAVPARTDLHPISGYLEFRQGESNKSFIVAARDDSEEEGEELFLLKLVSVDGGAQISKENTTARLRIQKSDNANGLFGFTGACIPEMTEEGSTVSCVVERTRGALGYVHVFYTISQIESEGINYLVDDFANASGTITFLPWQRSEVLNLYVLDEDMPELNEYFRVTLVSAVPGDGKLGSTPISGASIDPEKETTGITVKASDHPYGLMQFSTGLPPQPEDSMSLPASSVPHITVQEEDGEIRLLVIRAQGLLGRVTVGFRTVSLTAFSPEDYQSTAGTLEFQSGERYKYIFVNITDNSIPELEKSFKVELLNLDGGVSDLFRVDGSGSGEADTDFFLPPVLPHASLGVASQILVTIAASDHAHGVFEFSPESLFVSGTEPEDGYSTVVLNVTRTRGALSAVTLQWKVDSDLDGDLAITSGNITFETGQRIASITVEILSDEEPELDKALTVSILNVSSGSLGVLTNATLTILASDDPYGVFIFPNKTRPLSVEEATQNVALSIIRLKGLMGEVAVSYATIDDMEKPPYFPPNLARATQGGDYISASGLALFRVNQTEATITISILDDAEPERSESVFIELFNSSLVDKVQNRPIPHSPRLGPKVETVAHLVIVANDDAFGTVQLSATSVHVAENHVGPIINVTRTGGTFADVSVKFKAVPITAAAGEDYSIASSDVVLLEGETTKAVPIYIINDIYPELEETFLVQLLNETTGGATLGPLREAVITIEASDDPYGLFGFQNTKFIVEEPEFNSVRVNVPIIRNSGTLGNVTVQWVAIINGQFATGDLRVVSGNVTFAPGETIQTLLLEVLADDVPEIEEVVQVQLAAASGGGTIGLDRVANIVIPANDNPYGSVAFVQSVFRVQEPLERSSYANITVRRSGGHFGRLLLCYGTSDIDVVARAVEEGEDVLSYYESPTQGVPDPLWRTWVNVSAVEETQYTCATLCLKERACSAFSVVSGAEGPRCFWMTSWVSGTVNSSDFQTYKKNMTRVASLFSGQAVAGSDYEPVTRQWAVILEGDEFANLTVSVLPDDAPEMDESFLISLLEVHLMNISDSFKNQPTIGHPNTSAVVIGLNGDAFGVFIIYSVSPNTSEDGLCVEVQEQPQTSVELVIYRTGGSLGQVMVEWRVVGGTATEGLDFMGAGDILTFAEGETKKMAILTILDDSEPEDNESILVRLGATEGGSRILPSSDTVTVNILANDNVAGIVSFQTASRSVIGHEGEMLQFHVVRTPPGRGNVTVNWKVVGQNLEVNFANFTGQLFFSEGTLNKTIFVHLLDDNIPEEKEVYQVVLYDVKTQGVSPAGVALLDAQGYAAVLTVEASDEPHGVLNFALSSRFVVLQEANVTIQLFVNREFGSLGAINVTYATVPGIVSLKNNTEGNLAEPESDFIPVVGSLVLEEGETTAAISITVLEDDIPELKEYFLVNLTHVDLIMAPLTSSPPRLDSEGLTAQIVIDANDGAQGMIEWQRNRFEVNETDGVVTLVAQRSRAALGQVSLFMYAQNLEAQAGLDYMRTPQILHFTDGERFKHVDVMILDDDMPEGDERFQLLLTNPSPGLELGKNTIALITVLANDDGPGVLSFNNSGHIFLREPTSLYVQESVAVLVIVREPAQGLFGTVAVQFVVTEVNSSTESKDLSPSKGFIVLEEGVRSKTLRISAILDTEPEMDEHFVCTLFNPTGGARLGAHVQTLITIFQNQAPLGLFSISAVENSATSIDVEESNRSVYLNVSRTNGLDLTASVQWETVSETAFGMRGMDVVFSIFQSFFDKTALDWCFFTVEGSVYGVMLRKSSLVVYRWQGTFVPVEDLKVESPKTCEAFNIGVSPYLVITHGERSGEKPSINSVYMLTAGFRLVLIQTIIISGSCQVRHFTSDSQDYFIIASRRNDSELTQVFRWNGNNFAWHQTLPVRGVLGMALFSRGGSVFLAISQANIRQTSLLFTWSGTQFINFQELPISGITQVEALSSGDDVYLCFAKNTFLGNQNAIDIFVWEMGHSSLRYFQSLDFAAVKRIRSFTPASGIVHILLTAQDGSALYCWNSELNAFSFVLEAPAAHDAAFVTVKSLNSSKTLIALVGATDSHLYELTYVSSQSDFIPSLGELIFEPGDKEAIIAVNVLDDTVPEKEESFRVQLKSPRGGAEIGINSSVRVTVLANDGAYGVVAFAQNSLHKQLEELERDSLVTLNVERLRGTHGRITVAWEAAGSVSDVFPTSGVISFTEDQAMSMITLTVLADDLPELSEAVVVTLTQIVTEGVEDPLKGATIDQSRSRSVLTILPSDSPYGAVRWHTESLFNRVPEPTENITVVQLHIVRDKGLFGDISIHLIAKPNFLLHINNQATEDEDFVLQDSVIIMKENIKETHAEVAILPDEVPELDEGLIVTIAAVNLVNPNFPAEQPRVQRPRMESAEILIEENDDPRGIFNFHVVRDVGGVIIAHEGPPPLNVLQVPVVRMAGTFETVNVYWKATPDSAGLEDFQPSHGMLQFADGQVIAPILVTIIDDSEFELLETFTISLVSVTGGGRLGDDVSVNVVIAPNDSPFGIFGFEKKTVMVDGPLLSDDPDSYVTLTVVRSPGGKGAVRLHWAIEEKAKDDLSPLNGTLYFDETESQKSVILHTLKDGMVGEDRRFIIELTAADEVEISPVKGSASVIIRGDKSISEVGIASSSRHIIIGEPSATYNGTAIIDLVRGPGVSGEITVNWKILPPSRGEFVETSGQLTMLDGQTAATVVIQVLNDDIPEEKCHYEFQLTEISEGRMLHEASVSARITMVASDAPYGRFSFSHEQLHVSKAAQRVNVTVVRSGGSFGRARVLYETGSRTAEAGWDFVPASGELLFEAREKMKSLYIDILDDDLPEGPEEFVLAITRVDLQGRGYDFTIQENGLQIDQPPEIGNISIVRIIIMKNDNAEGIIEFDPKYTDISVEEDAGVITLPVLRLHGTYGHVSADFSSRGFSAVPGGYVLRGSSVTFQHGQNLSFINVSIIDDNGSEFEKQFEILLIGATGGAILGRHLVSKITIAKSDSPFGIIRFLNQSKISLPNPSSTMALHLVLERTGGLLGEIQVSWEVVGPDAEEPLPPHNGDFADPVSGTVSFGDGEGGVRSIILRVCPHEETEAEETFIVQLKPLREAKLDPRAKAVTLTIQKFGDPNGVIHFAPESLSKRRFSEPPPSDGPLLVSFLVTRSKGTSGDIKVHWELSSEFDITRDFLSTRGFFTIADGESDANFDVHLLPDDVPEIEEEYAVQLVSVEGGAELDLGKCTARFSVSANDDPHGVFALYSDRQSVLIGQNLDRSIQINITRLAGAFGAVAVRVQILSDNKEDPVATENEERQLVITDGARYKVGLVPLKNQVFLSLGSNFTLQLVSVRLLSGPFYGIPTILQEAKNAILSVPEEAANSQVGFESAAFQLMDIKAGTSQVMVSRKGTYGRLSVAWTTGYAPGSEIPEPIVIGNMTPTLGSLSFVHGEERKGVLLWTFPSPGRPEAFVLHLSGLRSSAAGGAQLRSGFTTAEIEPMGVFQFSPSSRNITVSEDAQTIRICVQRLFGFHGDLIKVSYETTAGSAKPPEDFEAVQKGEVFFQRFQPEIDFEITIINDQLPEIEETYYINLTSVETRGLGKGGVNWRPRLNPDLSVAVVTIVDNDDLTGAAVSVPVTAGTVAVDSTLLAMETGSTTHPNKSKITTIPYTTEVFAPVTETVTVSAIPEKLATAHSVISVKPDVVPGTVVASVYGTLSIGPPIVYVSEEMKNGTLSTADILIQRMGGFAGNVTITVKTFGGRCAQKEPSVWPFQDVYGVGNLTTWAVEEEDFEEQLLTLTFLYGERERKIAVQILDDDDAEGQEFFYVFLTDPQGGAEIVRGKDSTGFSAFAVIIISGSDLHNGIIGFSEESQRGLELREGADKNSQRLVVTRQPNRAFEEVQIFWRVTLNQTVTILQEKGANLTDELRFVAGVTTCTGGQTRCFIHLELNPKKVHQVEMPFFVELYDVTAGAAINNSARFAPIKLSKSGAPQSLVSFSVGSRLAVAHKKSTLISLQVARDSGTGIMMSVNFITQELRSAETVGRVLISPAVSGKDFVRTEGTLVFEPGQKSAVLDVVLTPEAGSLNKFPKRFQIVLFDPKGGARIDKVYGTANITLISDADSQAVWGLEDLLHRPLHEDILNRVLHNLNLRVATESTDEQLSAVMLIMEKITMEGRNQAFSIKSRTLLYELLCVLINPKRKDTRGFSHFVEVAEHFAFSLLTDVTCGSPGEKSKTILDSCPYLSILALHWNPQQINGHKFEGKEGDYIQIPERLLDVPEAEMLDGKNACTLVQFVEYSSQQWFIAGDNLPALKDKVLSLNVKGQSAQPLPNNNEVLYRIHAAEPRVVPHTSRCLLWNQAAASWLSDSQFCKVVEDASDYVECACSHMSVYAVYAQTDNSSSYNEAFFSAGLICISGLCLAVVSHMFCARHSMFAAKLLTHMMVASLGTQILFLASAYASPHLSEESCSAVAAVAHYLYLCQFSWMLIQSVNFWYVLVVSDEHTERRCLLFCLLSWGLPSFVVILLILILRGIYHRSMPQIYGLIHGDLCFIPNIYAALFTAALVPLMCLVVVFVVFIHAYQLKPQWKGYDDVFRGRTNAAEIPLILYLFALISMTWLWGGLHMAYGHFWMLVLFVIFNSLQGLYVFVVYFILHNQTCCPMKASYTVEMNGHPGPSTAFFTPGSGIPPAGEINKSTQNLINAMEEVPSDWERSSFQQTSQASPDLKTSPQNGASFPSSGGYGPGSLIADEESQEFDDLIFALKTGAGLSVSDNESGQGSQEGGTLTDSQIVELRRIPIADTHL

adgrv1

Adhesion G-protein coupled receptor V1

6199 amino acids

Receptor that may have an important role in the development of the sensory nervous system.

Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.

674.63 kDa

MPAVLALSGLLLMLLTVSVRSESAELRFQGQTQFVVNESSRAIVRLVVERVGDPINVTALVLLQGDDTGDFEATTAAAFLLSSESSKTIFIAVKDDDIPEADETFVFILRLQSSSNGVTVGTPNTATITILSNDNAFGIISFNSSSLITVEESKGRSQYVPLTLLREKGTYGTVTVNFEIFGGPNPASEDLSPDMGNITFPPGRSVVVFSIMIQDDKLPEDDEIFTVQLTEAAGGALLNPNRSSVQIKISRNDAPIRFSKSTLVVPENIGVISLTVTRGRTEDGLLIGSDDKTVSVAYAIITGNGAASATPLTDFVDLQTERMVVFLPGVHEADLRFSIRDDNIPEIAESFQVVLLEETLLGDAVLVTPSLTLVTIEPNDKPYGVLSISPSPIQPHIINEDLNLIYEGMIIVRNGGTHGAVSVQWNITRNSTDRSPVSADLNPAAGTLRFSEGQMSAVLPLNITQDSLPEEAEAFLLKLIPGSVQGGAEVDEPMEMVFFIQDSDDVYGRFGFHPRENQSIQSQPEGRFLSLSFLREGGTLGEVRLTLTALYIPARPLDPSRARDGVLNGTSVNTVLFSSGQSRAQLILPIRNDAFLQNGAHFRIQLDSVELVNITPPIPSMSPRFAGALNISLIITPDIANGEIGFTSNQTVVALEPEDSNSSLITLQLRRDGTDGQAVVFWSLRPTGENKEDVTKGDISPFTGSVTFLSGQSEAVINLTVLADNIPEINETIILTLDRTNVDNQILKPGFTSREIVILENDDPGGVFEFSPVSKGPWFINEGETVELRVIRAQGQLLNQLIRYTVIPSGTAQFYGATGILEFQPGEREVMVALVAKPDGIPELDETFSVVLSSYSTPASRLGNRREVNITVRKSDDPFGVIEFIQPDLDFTINESKALGCLLSILPPLEKSRGRFGNVSIFWILEPTYSGDVKPVQGEIVFAEGEYQKNLTLSSVADEIPEKTENFTITLLNATGGARLGNILSARLSIRANDDPIYFAEPVGQRVREGGVANFTILRAGLANFVTTVNYRFEYGDTSSEDFIPESNDTMLVFHFGEWMKNISVAVVDDNIPETDEPFYIVLFNATGDAVVYGQITATVVIEANDDANGIFSLDSAQKPGEEGKTNNFYVLRDRGHFGNVTIYWQLFANDTPLEPYQEFVNTSGFITFRTGEKTKPIVLEVISDKLPEFNEFYELRLMNVSGGYPGEGGKLANRDLNASVLIPFNDDPFGVFAIAPDSLEREVAEDVLSVNDMTSVTSLTILRQQGTFGDVRVAWEILSGAFPRGLPPMEDLILMASFPSAVELQPHSRRRHAGTDALFFSGRPGAYGSISAETTLLVPQILANFTLSVWLKPKPNTDGFVVSKGNGNGTVYYGVQVQTNDSHVTIMLHYTTIGSNSTHVARATANTFVEDAWVHVIIAVEDGIIEFYLDGSPIPGGIKSLKGEAIVNDATPIRIGSNPDGEQRFTGLLQDVRLYSSCLNRSQIHELHNQPAKTDLHNVSGYLTYRQEEKEKSFLVEVRDDQEAEGEEVFYLQLVAVQGGARLPMPRPTAILKVMKSDNANGLFSFTGACIPDIAEEGSMISCVVERTRGALDYVYVNYTVTQLDSPADLSNASDFANATGFILFQPGQLSEVLNLLVVNDDLPEVDEHFRVRLVSAKSGDGKPGSTPTSGASIDPEKAVNNVTVKASDHPYGLLQFQTTPVPVGMIRPALEEARVTVQEEAGVVRLLVARAQGLLGRVMVGYRTSPFTAAGSEDYEGFLDFLPGERFKYINVTIIDNSVPELDKVFRVELYNPNGGVDPYFASEGSGSGESETDFFLPSFHYHHANLGAAARIIVTIAASDEAHGVFQFGADSLIVNGTEPEEGRSTVVLQVIRTFGALSNVTVYWEADAASEGELVYRSGNVNFEVGQTVRSIYLLISQDDVPELDKTFKVRLTNASHGRLGKETTATLTVLASDDPYGLFVFSDNTRPVRVAEANALVALTIQRRKGLMGRVRVAYRTLRDTDTVLYSTPGVGRASEGNDFIAVVDSVIFSANQSEVNVTLRVLDDNEPERAESVFLELVSVTLIEGLQPRPVALSPRLGPRNVTIAQVIIEASDDAFGVLQLSSSAVSVPEYYTGPIINVTRIGGIFADVSVKFRAVPLTARVGEDYRVASSDVVLLEGESSKPVPILIINDVVPELEETFRIELLNQTTGGALLGDLTQAIITILPSDDPFGLFVFQAAPITIEEPALTAFEVSVPIVRNAGTMGDVAVQWRATVNGRPATGDLRPVSGEVMFSPGETLKTLKVEVLPDDVPEIEEIIKVELVSATSGGNIGLEKVVDTIVPANDNPHGTVYFEQAVYRVQEPLEGIYIANVTIRRSGGNFGMLEVVYSTLEVDIVSNALKEGRNFLVYYDSRLAGVPSNAIRRPINITTSTNVLNFCAAFCLRERACQAFSFTNTTTPSCFWVTSGVSQLSPSPQTFTYLKNTTATASLFSSQAVAGSDFITMTAQTTTMLDGSGVANLTVPILTDSLPEMDESFIIKILKVSLVNVTATARNLPTIRQPDTALVTIGMNGDAFGIFLLYSINPNATQEGLYLEVREEPKTTVLLVIERRGGSMGQVTVEWKYVGGSATPNADFNGTGETLIFAEGDVKKTLEFIITDDTEPENNETLQIGLVSTEGGSRILPSSDTVTILILANDNAAGVVGFHTASRSRIVREGESVTLLVERTAPAIGNVAVDWRIEGPLVPTTFADTSGTLFFSEGILNNTIVLKLLEDTTPEDREEYRVILSNIQTTGVTKTGIAALSAQGREAVVSVEASDEPFGLLSIAPSSLQVTTDEKNTTIRIYINREFGASGAVNISYETVRGSLQDLRQTEGALAQPGQDFRYVSNSVIMQDGQTSVSIPITIIDDDIPELQEFFLVNITSAVLITTLPTAPKLNTEGLVAEIIINANDGIRGIIGWQNIDYVVNETIGVLTLVAYRDAGTYGNVSLFFYAQNLEAQLGLDFNATPSMIYFVDGERHKFIEVQILDDAVPEGGETFQLILANPSAGLQLGENTTATVMILANDDGHGIISFNNSEHFLLREPTSVSGLGTSVATLYIIRDPPQGTFGTVTVQFTITDVNGSLYTDDLTPSSGFVVLEDGVRYKTLEIWAVLDAEPEMNETFTVTLSNPTGGARLGVSLQTFITVLENQAPLGLFRISPSINRTLDTMTVEEHMGTVFLTVSRSNGLESAVSVEWETRSGTAFGMRGEQPVLAVYQSIRDSFASVWCSVPSGDAALVLRLIKGLTQNQTVLYKWQGVFVPVEFVSIQNPKSCVGFTVNGSSYVAVSHADNTVSLTTNISLFRVQADLNLTLEQTFSVSGFSVKHFSTDLKQYLIASSEIFVWNRGSFFLHQSLELQDIIAAVPFRRGSSNVQHLAVCRNRTSAACFIYQWTDGRFQNPQPLALNTEVKQVESHQMGGDTFLFIVTEGLNPACEVFLWGSQQTVFQQTQSILVPGLFSVHPFTTPSGIFHLLLAGVNGSALYSWRSELRQFAEMLKSASAQEFLYLPVPSINSPKSLILASGKSSSLVYELTSVSNQSDFIPSSGELFFQPGVQELEIAVNVIDDDVPEEEEHFRVSLKNPKGGAEIGFRGQVTFFIPANDDTYGIIGFSQNSLMREVEELQSDNPVSLSIERRRGRFGRLTVHWSAYGSLDDIFPTSGVVTFSESQAVATISLNVLADDIPELAEKVTIVLTKVTTIGIIDPSRGASIDYQRAQANLTIRANGSPYGVIGWHLDSQYFITPEPQKSPSNITLSIVRDQGSSGNVLVYYSTKPALHLLPLNQASGGTDYVAKEATVVMMENATVVLVFLTILPDDIPELAETFFVNITRVEVLGGDTGAAQPSVKRPGLEIAEVTIQENDDPRGVLSFNVSKDVSGAVLAFEVPSPGNVLRLAVMRMAGIFGRLVLYWETQSVTASTEDFTPSSGNITFQDGQAMAYIEITIIDDTIVESTETFMVKLIRVIGGARLGVETSVVVSIPANDSPFGRFGFEELKVSVSEPQFLNDPASVATLTVVRSSGGEGVVHLIWLLQEESRDDLSPRNGTLIFNGTESKKTLVIQALADAVLEGEESFTIQLLSPKNEPVIDPVRGVATVVIRPDVGALGTVGIADSSRNVLIGEPICSYNGTALISLIRGPGIFGEIEIFWNITTAAVSEFEETSGKVVMKDRQSAATIQLKALDDEIPEERRVYQLRLSSLTPGSVINPDRQFASITMAASDLPHGLFSFSQASLRATEEDRAVNVTIVRSMGLFGSVWVSFHTEGRTAISGQDFGQSSGRPLFRPGESSRVIPLVIFDDDLPEGPEEFFLNITLVELLNASSMDFTVREYGLQIDQPPAIGNLSSLMVIIQKNDNAEGILEFDPKYVNNTVEEDVGTLSIPVLRRVGSYGQVTVQFVSKGLTAQPDSDYILLNGSITFQHGQTLSYINVSIVDDTESEFNEIFELQLTGATGGAILGAQLIARITIAKSDSPNGVVRFINQSAITIPNPNSTVRLSLFAERADGLLGDATVMWHIQGPNSNEVLPSMNTDIEPVNGTFSFRDGEGGVRSIDLKILPHGEVEVTEKFIIMLSVISGEMGVDPRAGSVTLTIEKFGDPNGIVQFTEQDLKERIYSEPSDSEGPLKVSVLVTRREGVMGNITVFWEILSDADTSGDFAALRGSVIILAGQRLAEIILTLLPDSVPELEETYTLRLTSVEGGAELDLNRSSTRLKVRANDEPHGVFVMYSQNQSVVVNAADRSRQLIISVNRLAGAFGNASVGYRISFTTPGQSFTEDTITGNILVKDGEREASIRVPVSSQVFFVTGFNFSVELTDVTLIGPLLGSPPRIQLESKLAVVSVPEVAANPVVGFASLALRVLDIESGQCEALVTRTGLYGNITVRWSSGFPPGQTPPGYQPGEILPRSGSIMLAHGQRSELISFTALNNISVVTAHAIYLTSVESESPGGARLRTGYTVAEVEPLGLYQFHPNSQHLVIEEDVQTITLYVQRFYGFRSNRSSVSYRTWPGTAQPDKDYVPVTDGQLLFDSRQTSASIRLSILDDTLTEPDEDFYVNLTSVRVLSTTLPLITAQPGIVQKNSISTVTIRANDVVSGFLSIGPAVKLISEDSVEDSPQQKLQLRVRRTAGLSGVVSAKIRAYAGLKTPLVDASQFHREHKGTWALEGEDFALETQSVTLLEGQNEVEVTVIMLNDQEPEGQEAFFIYLSDAEGGAQIVSVPDELGFTSFAKIIILGSDLQNGIVGFSLSSLSGQVLDEDSVNRTVTLVLQRQENRAFEDVLVFWRVTFSTTDHALVSHGVDLSKELLQTSGTSIRRKGEVLCALKLEVQPDKNPEYEVWFLVEVYKVGEGAAINQTARFANITMLESDDPRGLVYFAQGSRLPVVTLKATSVSLQIYRDASTASSISVEYRMQELPKVESIGPSLVWPAVAGQDFVMSEGTLTFEIGQSSAGLNIDLTPNIGSSNLTPKRFQVVLSDATGGARVHPEFGLANVTLVSDTETQAVWALLDQLHQPLEETIINRVLHALINKVSRDITPEQLMAVLDASSKILSDAEQTPLKDSSRGLTYDLLCAMANPNRTDTQGVSQLSEVAERFAYSLLTDIKCGAEGKRGITILDNCPYFTIAAHHWYPMQINGHTFIGKNTDTFTLPETLLEVPALPADSTAPSACYKVHFTEYSTEHWFLTNKKPSALNGKVFSVSLYGRGSKPLSEGQEVVYRIHTPDRRGKPKPSQSLCLLWNQAAESWLSDGQFCRLVDDTQNYVECACSHLSIYTAYAEIESLASFNEAFYAAGFICISGFALAMVSHLMCARFLMFAAKLLTHMMVACLGTQICFLVSAFRGRMFSEDSCAALGLFFHYFHLSQFGWMLVQAINFWQILVMNDEHTERRYLLYFLLSWGLPALVIIVLVVVLLGGFGWSIHSVYGLVQGDLCFIPNVYAALCTAALVPLICLVGVLVIFIHAYQVTQQWKAYDDIYRGRTNSSEVPMMLYLFALVTLVCVWAGLHMAYRYIWMLILLVIFNIFLGLYVFSVYFVMHNQLFWPGKATYTVEMNGHSSPDSIYQSTGAATVGGGEISKSTQNLISAMEEISADWERASLRPSSQPSSIFKPSPQDEAYITEGGFINTSLVRDEESQEFDDLIFALKTGSGLNVSDNESIHGSHDGGSMANSQIVELRRIPIADTHL