Abca17

Gene

Abca17

Protein

ATP-binding cassette sub-family A member 17

Organism

Rattus norvegicus

Length

1773 amino acids

Function

Promotes cholesterol efflux from sperm which renders sperm capable of fertilization. Has also been shown to decrease levels of intracellular esterified neutral lipids including cholesteryl esters, fatty acid esters and triacylglycerols.

Similarity

Belongs to the ABC transporter superfamily. ABCA family.

Mass

199.859 kDa

Sequence

MAPFKKLKLLLWKNFVLKKRKTLVTVLETLMPVLFSAIVLYLRLNSMPRNKANTNYPAVDVSLLPVYFHNYPLKSKFQLVYIPSKSETLKAVTEVVEQTFAVDFEVLGFPSVSLFENYIIKDPKSFYVLVGIVFHHDFNSSNEPLPLVVKYDLRFSYVQRNSISPPRHLFFQEDIEGWCTAFLYPPNLSQAPREFSYADGGHPGYNKEGFLAIQHAVDKAIMLHHAPKAALDMFKNLQVSVQRFPSGSHIQDPFLVILQNEFPLLLMLSFICVELIITNSILLEKERKQKEYMYLMGLENWLHWVAWFITFFLSALVTVSGMTVLFCTKMNGVAVFRNSNTTLIFIFLMCFAIATIFFAFMMSTFFQRAHVGTVIGGIVFFFTYLPYMYITFSYHQRTYSQKILSCLFSNVAMAMGVRFISLFEAEGTGIQWRNMGSVWGDFSFTQVLVMLLLDSFLYCLVAFLVESLFPRKIGMPKSWYIFAKCPLWRKKSFPVIPPLLVIGDPEKTSKGDFLQDEPAGHINAIEIQHLYKVFYTGRSKCIAVKDLSMNLYKGQITVLLGHNGAGKTTVCSVLTGLIPPSKGHAYIHGCEISKDMVRIRKNVGWCPQHDILFDNFTVTDHLYFYGQLKGLSHQDCHEKIEEMLHTLGLEDKRNSRSKFLSGGIKRKLAIGIALIAGSKVLILDEPTSGMDSSSRRAIWDLLQQQKGDRTVLLTTHFMDEADLLGDRIAILAKGELQCCGTPSFLKQKYGAGYYMTIIKTPLCDTEKLAKVIYHHIPNAILESRIGEEMIFTLPKKAMPRFEALFADLEQRQTELGISTFGASVTTMEEVFIRVCKLADPSTNVLTEKRPSLRHLPRNHRVPVDRIKCLHSRIFSLSSDQPIRLNTGFSLLCQQFYAMLLKKVAFSRRNWMLVLSVQILLPLVIIMLSLSFFNFKLRKLDNVPLELTLQTYGQTIVPFFIAENSRLDPQLSDNFVKMLVAAGQVPLRIQGSVENFLLKKAKEAPEDFDKLYVVAASFEDVNDHTTVKALFNNQAYHSPSLALALVDNVLFKLLSGANASITTTNYPQPQTAMELSETILYQGPKGHYLVVNFLFGIAFLSSSFSILTVGEKSIKSKNLQFLSGVSMAAFWLSALLWDLISFLVPTLLLVLVFFWYKEEAFAHPQSIPAVVLIMMLYGWAIIPLVYTVSFSFKTPGSGCVKLVAMLTFLSISPVVLVTVTSEKDLGYTELSDTLDHIFLIFPGHCLGMAFSNLYYNFEIKKFCNAKNLSDIDCNDVLEGYVVQKNIYAWESLGIGKYLTALAILGPVYITLLFLTEANAFCALKARLSGFFCKQKLRMLLNVTGAEDEDVLEEAENIKYHLDTLIKKSPLVVKELSKVYKEKVPLLAVNKVSFVVKEKECFGLLGLNGAGKTSIFNMLTREQPITSGDAFVKGFNIRTDMAKVQQWIGYCPEFDALLNFMTGREMLVMHARIRGIPECHIKTCVDMILENLLMCVYADKLVKTYSDGNKRVLSTAIALLGEPTVILLDEPSTGMDPVARRLVWDAVGRVRESGKTIVITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSRFGSGYSLQAKVRRKWQQQMLEEFKAFVDLTFPGSSLEDEHQSMVQYYLPGQNLSWAKVFGIMEQAKKDYVLEDYSISQLSLEDIFLSFTRPVPDTKENIQQGQAALDSSLSPSNSRPISSPPSSPPSSPPSSPPSRPPSRPSQPPSRPPSRHPSSPSQPPSRPPSRHPSSPSQPPSEPVLL

Protein

ATP-binding cassette sub-family A member 17: Abca17

Gene

Abca17

Protein

ATP-binding cassette sub-family A member 17

Organism

Mus musculus

Length

1733 amino acids

Function

Promotes cholesterol efflux from sperm which renders sperm capable of fertilization (PubMed:22237709). Has also been shown to decrease levels of intracellular esterified neutral lipids including cholesteryl esters, fatty acid esters and triacylglycerols (PubMed:15810880).

Similarity

Belongs to the ABC transporter superfamily. ABCA family.

Mass

196.02 kDa

Sequence

MEVLKKLKLLLWKNFILKRRKTLITLLEMLMPLLFCAIVLYLRLNSMPRKKSSTNYPAVDVSLLPVYFYNYPLKSKFQLAYIPSKSETLKAVTEVVEQTFAVDFEVLGFPSVPLFEDYIIKDPKSFYILVGIIFHHDFNSSNEPLPLVVKYDLRFSYVQRNFVSPPRHLFFQEEIEGWCTAFLYPPNLSQAPREFSYADGGNPGYNKEGFLAIQHAVDKAIMRHHAPKAALNMFKDLHVLVQRFPFGPHIQDPFLVILQNEFPLLLMLSFICVELIITNSVLSEKERKQKEYMSMMGVESWLHWVAWFITFFISVSITVSVMTVLFCTKINRVAVFRNSNPTLIFIFLMCFAIATIFFAFMMSTFFQRAHVGTVIGGTVFFFTYLPYMYITFSYHQRTYTQKILSCLFSNVAMATGVRFISLFEAEGTGIQWRNIGSVWGDFSFAQVLGMLLLDSFLYCLIAFLVESLFPRKFGIPKSWYIFAKKPVPEIPPLLNIGDPEKPSKGNFMQDEPTNQMNTIEIQHLYKVFYSGRSKRTAIRDLSMNLYKGQVTVLLGHNGAGKTTVCSVLTGLITPSKGHAYIHGCEISKDMVQIRKSLGWCPQHDILFDNFTVTDHLYFYGQLKGLSPQDCHEQTQEMLHLLGLKDKWNSRSKFLSGGMKRKLSIGIALIAGSKVLILDEPTSGLDSPSRRAIWDLLQQQKGDRTVLLTTHFMDEADLLGDRIAILAKGELQCCGSPSFLKQKYGAGYYMTIIKTPLCDTSKLSEVIYHHIPNAVLESNIGEEMIVTLPKKTIHRFEALFNDLELRQTELGISTFATSVTTMEEVFIRVCKLADPSTNVLTEKRHSLHPLPRHHRVPVDRIKCLHSGTFPVSTEQPMRLNTGFCLLCQQFYAMLLKKITYSRRNWMLVLSVQVLLPLAIIMLSLTFFNFKLRKLDNVPLELTLQTYGQTIVPFFIAENSHLDPQLSDDFVKMLVAAGQVPLRIQGSVEDFLLKKAKEAPEGFDKLYVVAASFEDVNNHTTVKALFNNQAYHSPSLALTLVDNLLFKLLSGANASITTTNYPQPQTAIEVSESILYQGPKGHYLVVNFLFGIAFLSSSFSILTVGEKSVKSKSLQFVSGVSTAVFWLSALLWDLISFLVPTLLLVLVFLWYKEEAFAHHESIPAVVLIMMLYGWAVIPLVYTVSFSFNTPGSACVKLVVMLTFLSISPVVLVTVTSEKDLGYTELSDSLDHIFLILPGHCLGMALSNLYYNFELKKFCSAKNLSDIDCNDVLEGYVVQENIYAWESLGIGKYLTALAVLGPVYITMLFLTEANAFYVLKSRLSGFFPSFWKEKSGMIFDVAEPEDEDVLEEAETIKRYLETLVKKNPLVVKEVSKVYKDKVPLLAVNKVSFVVKEEECFGLLGLNGAGKTSIFNMLTSEQPITSGDAFVKGFNIKSDIAKVRQWIGYCPEFDALLNFMTGREMLVMYARIRGIPECHIKACVDLILENLLMCVCADKLVKTYSGGNKRMLSTGIALVGEPAVILLDEPSTGMDPVARRLLWDTVERVRESGKTIVITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGISYSLQAKVRRKWQQQMLEEFKAFVDLTFPGSNLEDEHQNMLQYYLPGPNLSWAKVFSIMEQAKKDYMLEDYSISQLSLEDIFLNFTRPESSTKEQIQQEQAVLASPSPPSNSRPISSPPSRLSSPTPKPLPSPPPSEPILL

Protein

ATP-binding cassette sub-family A member 17: Abca17