ATG11

Autophagy-related protein 11

1429 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy (By similarity). Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32 (By similarity). Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation (By similarity). Required for ATG9 anterograde transport from the mitochondria to the PAS (By similarity). Recruits also the ATG19-prAPE1 complex to the PAS (By similarity). Required for the Cvt vesicles completion (By similarity). Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236). Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).

Belongs to the ATG11 family.

162.227 kDa

MALQVLIAHTGLRLEVDTAQFSILDDLKTWVSKKTSIPPQHIVALNPHGRTVKITNLHTEKEIFVYDIRISSPGNTNLITPIPLPKRYAVPNAPNTIDDVQSITSWQELYKDRRNWAMRLVEDSGQMSSATLARYSEIDVIIKCLDAAVANLEISIKQIEPKYNDLKKWVAPALEEHGNLVERWEQYLDLAKSTPVSPSMVKFMTGREINKARPTLEDLIELDTAKKAGKLAPTAHRRFSDKANQLGNTASQMYQSLESLIANFETLMSRSALSHSTDSAQLLEDIEAVVKQMDSDYRAALGYGNTQRDVAQASKTASVHTEHLVPTLKKRVKEMEELLHYGTDARNSVASESAKFMRHVTEITSLHSNVKSQINVLNQSEDDMTTFDYLRLIHQLPYMYAAFVAEAVRRREWVDKVKTDSSTLANEMALFQDEESKRRRKWQKMIGSMYGPDLDTNVMGLEVNLLGEDTPWPALTKEDLTDFIQILQEQPVDQTVLDDIVKLVQELDSPTKQQSKRLKAFKNGSIHEAALGRSGLMIRGDDDLLQSLQEDKGKLENKLKTAESRVRRLEDLLHRQSQASRPGNLFQPQGSQQRERVNSASSVRSSRFDDRRRSSEGIDPLMRRITQLENELREEKQRSVNLQQELTTQSNNHEDVKGQHEDLKAQHEDLKGQMAEINTTKQDLLENMEALEREFVEERKNLEIEIKTLKARLEDTEDEIEQFDESRQHEKAGLVVRVEELEAELEQVNKQRQDDALKAQGQVEFLRKETRIQREQQEALEQQIQSAQEEVQNVSRKLSVAEEALDDHWQALTRLFSELSPDGTIPDNVVDLSNLLLTQAGTLVEKSRNSEADIELLKTQVEHFSSAISELREQVSQKDAKLSEDEMTVIHLRENIAEEQAKVSALEQELADGREQLTELRAKLSDGETGPEALQTRLEDEEKKVMTLTEEVASKQSHVGSLEEELRMFQEKVESLQGKISHMNSHYEHRDEKTKDLTQRLYSQNDRMCRLLERVGYAVTRKDGEMTVNKIPRAERNAQNLADSTDPSASIRKSGTLSRVLGDSVDLELLYWFNNSDMQAEDEKYEEFMNNLGKFDMELFSETVYRRIKEVEHMARKWQKEARSYRERAHILQKDSHEKIAFKHFREGDLALFLPTRNQQAGAWAAFNVGFPHYFLREQDAHRLRHREWLVARISRIQERVVDLSKSLQPSSETESINDEENDNPFQLSDGLHWYLIDALEDKPGAPSTPGMGKSTVAANTVEATANIHAHGVGGKGKSRESVTSIEGINKTLSKSLESRRSSTNSKKALPFQLGGTTLLKNSALASETNSLRAHNADTPSGTSPTQGGHLTSTNASLGQKNQRVDGPIRQPSDESSTQGGGAKADEQPRSVVQREDSVESPTRRSVVWDSLWSVDYNYESGSRRWLGG

ATG11

Autophagy-related protein 11

1423 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy (PubMed:28830792). Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32 (By similarity). Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation (By similarity). Required for ATG9 anterograde transport from the mitochondria to the PAS (By similarity). Recruits also the ATG19-prAPE1 complex to the PAS (By similarity). Required for the Cvt vesicles completion (PubMed:28830792). Plays a role in morphological differentiation and cephalosporin production (PubMed:28830792).

Belongs to the ATG11 family.

159.908 kDa

MATQVLIAHTGQRLEVDTAQFSHLDDFKAWVGRNTPVAPKHFVALTPQGRTVKHASLYAEACCPSQKEIYIYDIRMSQAPSSDGSPSVVSQVPPPKRYSIPNAPNSIENVQAIASWQELYKQRRAWAVHLLEDCSAMDATARARFEEMDVMIKCVDAAVANLELSIKQIEPKYTELKKWVEPALEEHARLSTSWQQYLALARNTPVSPSMVKFMTRGQASKSNATLEDLIEPDTAKKAGTLAPTAHRRFNDKATELDRAAKKMYQTLDALIADFDKLMSRSVLGRSDESTQLLQDIEAVVKQIDSDYRTALSYSGSQKDVAQASKTASNHTERLVPNLKKRAKEMDDLLQYVTTSRNTVASDAVEFMRAITEITSLRGKLKDNIGILNQSEDDMTTFDYLRLIQQLPYMYASFLVEAIRRQEWNEKIKADSSTLANEMALFQDEEAKRRRRWQKMVGSTYGPGLDTNVIGLEVSVLGDDNSWPSVNKDELVAFLAALKDQETEEAILEDVGRLIQELNSPTKQQSKRLKAFKNGSVHEAALGRSGLMIRGDDELLRSLQDDKSKLESKLKTAESRVRRLEDLLHRQSQASRPGNLFQPQTNSIHERNDSASSVKAAPTDRQRASSEGTDTLLRRISELENELREEKQRSSRIQNDLSNRATQHDDMKNQIREVNSTKKDLLENMEALKREFVLERKSLEDEIKTLKARLEDTEDEMEHFGESREKERTSYEERAQQLEAELERIDKERRDEMLKAQGQVDFLRNENRIQREQRDTLERELQNTKDAGHATSKRLEALQEAADAHLQSLKELHSQLTGNDPVPDDGDLADVIQTKAADLLARLQNMESDTSLIRGDLDRTRDQVKELREELASTKDKLATEEAASIHVRECVSEEKAKVKALEHELAETREQLSRARARLADGETGSETLQKRVEEEEKKVASLSEELASRQSQVGSLEEELHLYKEKQEAACARASELTQRHETRDERSKELTQRLYSQNDRLCHLLERLGYAVSRKEGTMTITKVPRAERAAQNPNDSSDPGTSLRKSGMLGAKALHESADLDLLYWWNSADAATETEKYAAFMSKLGDFDADLFADTIYHRIKEVEHKARKWQKEARSYRDRAHIAQKDAHDKIAFRHFKEGDLALFLPTRNQQAGAWAAFNVGFPHYFLREQDSHRLRHREWLVARINRIQERVVDLSKSLQANDSASINDEENDNPFQLSDGLRWYLIDAQEDKPGAPATPGMGKSTVAANNVEATANIHTHMAGAKGKNRDSVHSIEGINKTLSKSLESRRSSSSSKRALPFAGAGAQALLKSNPIASETNSLRAAAPETPVATSPVQGGLLSTGEGGRPQPGAAGSSSARRPNDGPGEASGNGDAAKTAEPRRMLDRQESTGSPTKKSVVWDPLWSVDYTYESPGKK

ATG11

Autophagy-related protein 11

1395 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

156.36 kDa

MATQVLIAHSGQRLQIDTSRLTTLDEFRSAVSRSTSIPQNCIIALVPPGKALRPQAIQMEKEIFVYDSRMTQTGAPGSPFPVKLEIDLPKPYAITNPPNDIIDTRSLESWQDLFRERRVWAHRLSEDCEGMEKEAHDQYEAMDNMLSCLDAAVANLESVVRATENKYEDLKKWAATEQTGYNDLVTRWEQNLGLARSIPISAAMVRLMTGKDVTGAKGRPSKQATLEDLVDLDCARKEGRRAPTVLRKFNARIADLEKAEGRLMQNFEELEAEFRRVISRSVMGHSQDATQLLQDIQALAGKVENDYRTTMDYSTSTRDLLQASKIAQTHTEKHLPSLHKRALEMDGMLRYAIKARNALALEQAEFMRSIADVSKLDMQVKSLINAIAEDEELATFDYLRLIHQVPYMYAAFTAEAIRRKEWFDKVKTDSTTLANEMALFQDEEAKRRRKWYKTIGDTSYGPESLSTDNNVPGLEVNLLGEDELWPSTSRKDLEEFLDLLQRQRADASIIGDVGKIIAELSNPTKQQFKRLKAFKNGSVHDSALGRSGLMIRGDDELLRSLQDDKTKLETKLRTAESRVRRLEDLLHRQGQASRPTLGNLFQNPSQQLPERSGSAQSVGSPGPIGDRRQSDEVGNQLVQRVAQLEKELQEEKERNAALERDAADRTTHTNDIKAQMDDVNATKKDLLENMEAQKREFLVERKALDEEIRNLKARLEETEDEFHNIDESREHEKTSYDEKVQLLEAQLESLTKEKSDDALKAQGQVDFLRNETRLQRESNEALQAQIQASQDELGLLNKKLKTTNEAADVQLRALRELYTTFVKSAGIPEDVNDLADTVLNNAAETLAKVQNLDADISIMRSNLALAQDVAKDLRAQQANALEKLAKEETTSMHLREQCDEHKAKVNALEGELADGRKQLDELRTQIAQGETGSESLRTRLEEEEKKIVRLTEDLASKQSQVGSLEEELRLFQERLQDSQSKLTTLTLRTETRNERTKDISQRLYSQNERLVRLLERLGFSVSRENGVMTIQKIPRAERSTMNLAASSTADAKSRIASEPADVELLYWMNATDVQGETEKYDKFMSTLGSFDVDAFADTVYRRVKDVEHIARKLQRDVRGYREKTHALHKDAHDKIAFRNFKEGDLALFLPTRNQTNGAWAAFNIGFPHYFLREQEHHRLSNREWLVARITRVQEKVVDLSKSLDTTESINGTSGGAEDDNDNPFDLSDGLRWYLIDAQEDKPGAPSTPGLGKTTVASTKVEAKGDMQTQPRSTPGGLAVLGGAKPSAVDGASKSLSKSLESRRSSTSSTRRPLPFAGALSRNAPGSETNSLRAVATTAPGDGAGSPSGPTSPKPHLAHGEDQDVRLAALPEPQQQRVEVRNDSGGGAIDSLLGPT

ATG11

Autophagy-related protein 11

1313 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity). Involved in glucose-induced micropexophagy.

Belongs to the ATG11 family.

151.234 kDa

single

MDSSRHGLHPLQNSLLHQSQMDIYNSITGIRISAIPYNFNSYDQFKQYISASFGIAPADLFLLTAFGIKLKFSMIMNGDVREVYVFDRRFYDGQQMVDDKLDTALESLNQCEMLNMIKPMRSPLENADILRFVSYLKDITNRPNLSTEDLDLNKLRLVLNSLKRSSGWAAALLSDLKKTNYYKKVNEEVLCDNKKEIEIILISHNALIQYTNLMFKTLEKSFNESVDSLIMLQEQSLLENWKSYYQILKGVRFKGNYVLSDLLDEKMLENVAADSKALMGNVNDKLTRLRSRIDSEIISKRVMINDLYESLKKKYLDVPNLNSNSRTENDSDTLNRLTELVNQVVKDSKELPILDELLTTSGGNSTTLSAESVKKINVLVSVFETHSSTIIPQITELSNKLYDEKVEALNLKQDLQRTLLSDTIHKIVGVQLSILKATNLINNDLSKNISNLDFNELKMSIVKDLPLVFGLWLAGNLKKLKWLENFNKVAFKANEILEMLKFIESNYRSKWIDGFSKTNPCVNSNQGQRILALQINEDLKQQFVRDHLASSRIVLKTGSNVPTPGGSKGNSRAPTPEHDPHPPHLNAINKLLHNFNKDYNFGNLRQASEEVVRTHSPATKRDDRFGNQFWLTLIDNITTEDFYHYIDSLKENKVNIKVIKQLEKNLTDLGLGRIYETSNDKVISAGGGTIGPLNSQDTSYMNLLKKFLKNFEINDVTIQINISTLETENGNNNEKEKEPSFSNHELLQGYQRRVKKLESLLYQQSLHQSGPPPINMAYPPIRDYQQRSSANLMTSATATEMLMDTHARIHDTDMKQKRENVDEIQVLQTRIEQLQANLEQTSKERDDEREQKEILHLKLMKRDEEGDEDEKINGLVAANHQLQIRLEALQKQNQELQSLQERNNNEIHASQEREIEALKKQVVQLTEEKTQMSDEKDRLDLSNEHWKTQYEEAAMMKKDLLDNMTAQEQEYKNELNTHIKEVEDLKVKVENLEDEEANLIEIKENYESKLAQNESHFEELESIIKSLYGKLRLVIERTFQNVVTVCLMLEAIGLLMKRDEQYEENDPSNGIRIHRVKGLRSRRRSTTSKAASPLGNDEILELSSQIVAEADKQLVYFHQEPVKELESLETVLDFKFNQDFDKFTRLTYMDQKLLVESVTKRFKDVEQLARKLQKESNYSKTEIDGLIKEVNTRISIKDFKVGDLVLFLPTRDDTINMNMANTVEAVNRRASTVASFETYQPWAAFNVGAPHYFLINDVSKIDLNGRDWVLARIESMEEHKVTREGHRRNVGNPYNLNPDAVWYGVRAKEETVG

ATG11

Autophagy-related protein 11

1299 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

149.155 kDa

MNISIIQNNNPLSMMSSVYRQNQSQDTNLPSALTIYNSLTGAKVVASAYQFHNLEALKQFIGMSFNVATENLFLLTPFGIKLKFSMIVHEEISEIYVFDRRYFNVNNIEASGNMDNVNDLLAELNQTDFINMIKPLASPLLSEELSVFVEKLTLVLENTTQIKAVDINLNMLRMLLNSLKRNSGWASALLSDFKKTVAFDECTPEDNDLETILTSLNVLIQYVGLVFKTLEKKFNDSIDALVLLQSNSLVDQWRDQYALLKRIPFEFKSGSSNVPEKLFLSQLVNESHLDKCAEESRRLNKSMNERLVMLRSKIEADVIKPRQELLQEYNGYMSQYIRPETDATQKTQKIQDCKRILAELEVHVSKLIQSSSSLPSFEELITTASQTSTTLSASSIANIKKLTQLYKYQESELVPYIFQLANNLYDIQINKLNARKELQTKLICSTLINITKIQLNIMRLSTVLNTEVAKNIASIKENELQLSVVSDLPLMFGIFVIANLNNLKFGISLNNIVKKANEIFEMLRFMESRNRAKWLKEFLASSGADKVEFLHLDEEARERFINENMLSYKLEQVDAIRSKKSPSPVDHPASPVSGQEKHYLTSINRLLHNINGFPAPRPTATELPKQRETNIMTNLARNISVKSIVSYINTLRKEGIDLNIVNRLEECLKDFGITYGAIERKAIETEDGEEIVVKGKNAGDLGTFDVNDVNYMRLFKKFIKSFESEGIVININVNQQDSVSNDELIKGYERRIRKLENVLHTRNFQQFNEQWSRHRPVHTLPNPVSRRQSDMSQEPAVHENTILFNENVVLGRKTIDLPPSHYGERIERLEKENERYRGEIEELKKGTDLAELDRLKKEIEDLQKADMEKDKRLAALEEENKNLKESNEELTNSNKELVNMCEELKSMKSDLLENMTQKESEFGKEAKVNQQEINELKLRIEELEEDESNLVNVNKTLNERLAIKDGLLCQLYELVQGAYGKLNQMSGEIFSNLTRVCLLLESIGLLLIRETPSFDNHPGTLTIKRVKGLRSRKRQIKQASDSTHNGNLQNDTFEDSEHIDNALMEVVSSEVVPEAEQYLHWVDTNVLNYTISSDLGIEDEIEHKKNESSLIDMSLCEESSIEKKVKKLLANYESFNVEQGFQNFLRFNHVDNELVIERVFRRFSDVETLARKLQKDKTQQKQELKMLTAELDGKIAFRNFKVGDLVLFLKTLTPANEELGGGDEQPWAAFNVGCPNYYLKNTKGEGYIELSDRDWLVGRVSKIEPRQVTEQNFHSKTENPFRLAKSVVWYYVEAREVKE

atg11

Autophagy-related protein 11

1285 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

145.16 kDa

MTARGKNVKIQTLATENEIFLYDRRYVSEQDNADLPKLPSPQPLVLDKPPDTLSDRNDLQAWRNLYAARKTWAAELTERCEMADTSIRELNERTGIVNRAASVALENLKTHVAALENRFQEAQAWAKELSREQKSALEEWKRALANLENIPARKEFSFLGRPSTPKKDADRATGTLLDYVDAVEVQKAGPEASAASSRFAQQIQDIERAVGEITAGTQRLLDDVPNSRTDTADGLLQEIEPLSRKIQSDYEHVLGLSNNSKTLANISRLALNHTQDILPSMLEIAMEIRESLAAAVRQYDAATKSALGRTKLISAIQSRLADVQAHIANLTFQSDAFDLLYSVFHMPLVYGSVLIESVRRHEFNEKMKSDSLTLAEELSIFQDEEQRRRKKWVKNMEDFLSVTDTTTPGIEVNLRGHEFDWPIVTRKDIETYIEDLRSNPGTANAAQELAQAFKELDAPTRVQRRRAKAFKQGSIFDLSRSSLLLHSDEIVRSLRDEKLKLEEKLRGSESRIRKLEDLLHRHSHLGRPSSGNFSIDFPASPASPHPDPMSRRSSVSSRRLSSNQTSEEKNLVNRIVHLEADLAIERETVQRLQREADAERQSNTNKMQEAQSTKNDLIGNLEARQREFSDERRYLEGEVKRFKIRVEELEEELDRLTDSRDHEKQDADERMHQLELELQDAHARADAEMRKANNLLEQMQSHREAADRSKLRMDELEKQATERTQKDQEVRHALQAAFMNLSPGGSVPDEIVDIIKAIDVLSEGLTIHAKTAEDNAMKAAAENKTLIEQLEKMESNYENAKSASEQYQTQLTQAREEVEQEQSKVKAIESELNDERASLLELESKLAAGETGAGALREHVAEEEQKLNNMSQQLAETEARARRSEEEALQWRKRAEALSESDKQVAARIDIRTARLEELSRQLFGQVEKLERMLEQLGFTVIRQDGEIVVQRSSKVNALSATADTLSQSGVVSVKPDPSLLNWMQGEHPEEETERFNAFLESLHQFSVDIFGDAVVKRVKDIEVLARKWQKEARGYRDKYHRMQSEAHDKIAYRSFKEGDLALFLPTRNQAIRSWAAFNVGAPHYFLREQDVHKLQARDWLLARITKIEERVVDLSKSMNGGNPDRRSIGEASDGASIDDENPFELSDGLRWYLLDATEEKPGAPATPGLGKSTVAPAHVDAKGSIRLKRTPAGGNVTKTLTRSLDSRRNSSASASIKRGTPPSRANDSTTDLVRPAQAESESIAAATDSKSQSQSQSQERERRQEAQGTAVIFDEVRRDQLQGP

ATG11

Autophagy-related protein 11

1282 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

146.453 kDa

MVAPISYLTLYNAHNGDSVKIPKPIRFHSLNGLKSFIHESFTDYIISDIENIFLLTSFGMKVKFNIINELNDIYVFDKRLFSGARDETIINAYVNQNEGGYKEMIKPTPSSLVKLEKTNIKQMTSSLKVNDGWSKALFQDCLGVVGQMKAYVKQINTIFKCLNIIFQFGSNFINGIEKSFNNYLNYIKLLNLKTLHRSWNGYYNNLRKFPSFQLKNGTGNIKISDHLNTSELEKSSSFVSKTLPLVINKFNEMSASINSVNDDKVNVDKLIESLRNESIENFKDYDTGSEDIIKDVSRLSQLISHDIDKLSTNVSISLDWVYRIHKDEISPKIFDKATGLYKILQNLYLFKNKIVDESLSIFGKIANLQMRMVNIKNDLRILTNADDNNDIANENEISIHVINNIKSAEDYLSLTIDLPLLFGFMLIEKRRQFEWHEFYSKGIVNNVSEQLSVIIDHEKIFRKLWLKKFGNFLSILNSKDENDALRTVLPSIDVTLVNGNAESNSTFGIINNIQVERDDISTYINALEEYSNAGTTSSPSSKKFSELMKKNFQDLIKCTNNMKRVTKMVSSLSSFTSPVANEIKNNDKLLANSKDENNDKQAEGGGHMSELGEVDYDINLVKGLKIRIRKLENLLHQQQYKDLSNWPVTRSNGANATSTSETDGKFSLILDSNQKTSTSSNSKIDPTNLLQRRQTLPLKLGHEKPTTSQQSNHLDVSTTIDKHLDNIRLKKENNELTNENLKLSNTNRTNEKLIEALNKQISNLKTVNDDQNKHHEEKLRKRDAENQQTITRLETELQAFKPQNNKEVVDLKDKLSLRDAEILDLRKDITRLHDVNEGFTEEVTKLNEKIATLQSDINDVNAMKKDLLSNMASKETDTINHRISLEEEIKKLHSKIEELTEDYENLMDLTQSKHNNLDIMVNYLNNMIIHLLSSIKCLVEQQFETFIEFCFILESMGLLLIKEHNNNKNLDEYKITRVKGLKSKRNDKIVPTSANGNVLDETPIVSTMGNMPTSKVVDDINKIIGWVDDIQSFKNISTKSSEDGDEKSCSANTAGSVSSSVIDDLPEEITNLSVEETNKFNRQSLELVKLFRDIFKSSNGSISKFEDFINTIRFKENICINQNQDDSGVSNKFFLGAITKRFKDVEGFAKKLTKENKSKAHELSQLIGKLNCKISMNSFEMDDLVLFLPTRIDRAEEIDENFQPWAAFNIGAPHYFLRVQKNEGNKTGITHSIKDKEWMVGRVTYIEEHTVTDANFNDKDANPFHLSTGVVWYVVDAKEEIF

atg11

Autophagy-related protein 11

1264 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

143.022 kDa

MTARGKNVRIQSLATEDEIFVYDRRFVSEPENVELPELPSPEPFTPDTPPDTLTNQNDLQAWRNLYMARRSWALGLVERCGAMDKSIHEHNERTDIIHRAAGVALENLKTHVGNLENRFQEAQTWANDLLKEQRAALDGWQRALTTLESIPAPKVFPFLGRPSTPKEHRDRPTGTLRDFVDANEVQKAGAEAAAESSRFARQIDDVAEAVRGITADTQRLIDDQLPSGADAADGLQEMITFAKKISSDYEHVIALPNNQKTLANISRLALTHTQDLLPSMLDISAEIHAGLEEAVRRHNTAMKVALDHMRTISAIELRLADVQSQIINLNVQSDAFDVVFSVYHMPMVYGSILVESVRRREFNEKMKADSLTLAEEMAVFRDEEQRRRKKWLKSMGDFISLTETTTPGVEINLQGLDYEWPEVSRNDIESYIEHLKSRPAMASLADGLTQQYKDLDAPTRHQRRRAKAFKQGSIFDLSRSSLLLRSDDMLRSLREEKSKLEEKLKGSESRIRKLEDLLHRQSQLSRPVSGNFNLEFPSSPASPYPDELSRRSSVSSRRMSANQSSEDKTLAQRIVTLEAELNAERETVQRLQKEAHAERLSNTDKIQEAQSTKRDLIDNLEARQREFDEERRYLEGELKKYRLRTEELEEELDRITDSRDHAKQDADERINQLETELQNLHIHTEEELHRANDLLEQMQAQKMTEESLQQRINELEKQQSEIKATEQENLQTLQAAFMNLSPGGAVPAEIPSIIKAIEVLSEGLSIHVKNAEEKMAEAVAENKALEERMNQLETEVQDAKQSAEQRESELAQVRGELAQEKEKLAAVQSELHDERSKLNALQSQHADGDTGTDALRQRVVEDERKLGILSQRLAEVEAQARESEKEVCAWKNKLKAISESEREATTRIEIRGSRAKELSQQLFEQVEKMEHMLEQLGFTVIRQDGEIVVQRASKVNASSGIGDSLAQSGVVSVKPDPSLLDWMQAETAQEETDRYMAFLESLYQFDVDVFGDAVVKRVKDIELLARKWQKEARGYRDKYHRMQSEAHDKIAYRSFKEGDLALFLPTRNQAIRSWAAFNVGAPHYFLREQDAHKLQTRDWLLARITKIEERVVDLSKSMNGAHPDRRSIGGTSDAASIDDENPFELSDGLRWYLLDANEEKPGAPATPGLGKSTVAPAHVDARGSIRLKRTSNGGNVAKTLTKSLDSRRNSSSSKKGPPFAISQRANESTAELARPAEANTPLSPSAQEAASTPEEVRRDQLQGP

ATG11

Autophagy-related protein 11

1219 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

141.693 kDa

MSSNIINAITGELITIDITLFISLNEFKKFLINRWQIDFNNLLLLLPFGNKINDRIFIDLIGKKNDQSTIYVFDRRLFSLVNNPDNELSSDYLTNIKNLLKGINHPTNNLNQLVKPVNSPYEEVEINEKFLNYHTITSLITTNLGWLSALEIDMHYFQIQISDTLDYIKNIIESLKICQNYLELYCYDVENLYNSNVKFLNQLANNEILKNWLNYYDNILTKLSDINGNKLSSYLNKNELVSISSKIEELDQRVNSNLKKFKIVIDKNIDLRNNINKEISSLSEKITPSSEKYKLEETMLEKFTELVKNLRNDSKVILEKDENEFDKNYMQNLAKSLEKDKKVTVTNLLTISKALYSQANDISEIKSKLQVDSIKLFGQISFIQIETLNIKKLLLNELNKDLEKYQGFELKLAHVQDIPLVYGLYSIENYRRESWVLQINYKHLDFNKSLKTIVEKEKSTRNKWVDNFGSTAVYFTEDMDTLRDFNYLNNIAKGNQSMIKKLEELFKNISNESHNKNLVFIETYIKEVEDLDLDKDVIELFKRYLAVAQGFVIEQPSTKNIISDKETGELINGYQSRIKKLELLLHSARYSNVESWPTGLLNYSNVKLFRNNVATVNSKLSLQSDYMGNISYGSDQLRIKELENVNKQYKTDFKALTDENKLLKDKVTKFNTDISDIQIERNAYKETLTKLNEELSRLTSIEGDFEKHKGEKEIELKIKIDGLVDSNKTLLNQISDLKIESKELESSNRDLLAQLNQKREEHKVLEDSLKQRENEGLRYKDEYEAKLKELTEKFEADRRALEDEIKAAKEQNMKESMEQQTEQSANQSIDQSIEQSTEQSTEQSTEQSMEQSMEQSMEQSVEQSMEHSMEHSMEQSEKQNMGQNDATIDNQSIETPTSEDMHSLDEQSPESQLLKSNTTELQPIKSQELAEDSKAIELKNIQEMLVSKLYEIFSSNVFILENIGLLLTFDEHDNFQIRRVKGLKKNLNQSVLEETGLLNEIEMPVKSDVFSEVKTLFSNYKETFDSRSYISLLSKINQLYDCKLYETAVIKRFEDIELLAKKLAKENKAKKNLFEKYRCERITLKNFEVGDLALFLPTRENCITEDVSVASWNSSFSSVDLSTPPPFGEPITNQSHSGTAKDKNKHNLEKRPWAAFTAFEETARYFLKDPENIPNNREWFVGKIMHLQRFVVEDHISNPYKLPKGAVWFQVTATVVSHQ

ATG11

Autophagy-related protein 11

1178 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for ATG9 anterograde transport from the mitochondria to the PAS. Recruits also the ATG19-prAPE1 complex to the PAS. Required for the Cvt vesicles completion. Plays a significant role in life span extension (By similarity).

Belongs to the ATG11 family.

135.011 kDa

MADADEYSTAPTQQEITPLQTTATIINAISGECITTNVDFFVSLDKFKQFIARKWKIPPDQLLILLPYGNKLKPSMFKELLINRSFTLNDFYVYDRRLFSLVSKPTSTNLLTSKDSNPMNSPNSNDLTETLEYLIKNSHISQYQGSDTIMIKPMPSPLEDADVDLSRLNYHSVTSLLTTNLGWLSALEIDVHYFKSLIPDIIAHIKRIFDGLTVCSQYLKLYCFDVESLYNSNVQFLNQLVDNGMTSKWEKCFNDTLSKLTALEGDSLQKFINIESLLENEKSVKILNHSINGKLNKIKREIDENASFRDIITVNIDRLRQIFTPNESKFELEDQMAESFEVLVSEMRTRSRNVLDKEEEEFNSQEFLKSMNVMLEKDKKESVKTLFTISQALYSQIGELIDLKKSLQKHAVAILGNIAFTQMEILGIKRLLLNECNKDLELYKKYEVEFAQVEDLPLIYGLYLIEKYRRLSWFRQILSFISNFNQDLELFKQNELRTRNKWVKNFGSIATVFCEDLLSSSDFKRLNEYHSHTSPPNEDEEDENENSIANYRQDLVKVSQAIDNYMTQIKETDVSEPIIDLLSKTLFETKRFHIIYSNFKNNNNNSSNGNSISPEGSIALKSDDVVKGYKTRIKKLESLLHEFQYSDIGHWPQGVLNTHLKPFRGSATSINKKKFLGASVLLEPANISEVNIDSVSQANNHQIQELESNVDDLLHQLQLLKEENNRKSMQISEIGKKISDLEVEKTAYRETLTNLNQELARLTNEEQSHRTEIFTLNASFKKQLNDIISQDNEKIEKLTGDYYDVSKSRERLQMDLDESNKKHEQEVNLLKADIERLGKQIVTSEKSDAETNSSSMEKGEKFETIPLAEDTGRENQISAYTQTLQDRIFDIISTNIFILENIGLLLTFDNNNNIQIRRVKGLKKGTAQSNILDESTQMLDAHDNSLIKSPVFQKLKDEYELIKSVANGSEKDTQQSIFLGNITQLYDNKLYEVAVIRRFKDIETLAKKLTKENKIKRTLLERFQREKVTLRNFQIGDLALFLPTRENVNSVGSMSSSTSSLSSSFSSVDLSTPPPLDAMSIQSSPSVIHSNVINQASISGRDKNKLMRPWAAFTAFEESTRYFLKDEKGLTKGKEWFVGRIVTLEHFVADSPSNNPFRLPKGSVWFQVTAVVVSYQGV

ATG11

Autophagy-related protein 11

1178 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for ATG9 anterograde transport from the mitochondria to the PAS. Recruits also the ATG19-prAPE1 complex to the PAS. Required for the Cvt vesicles completion. Plays a significant role in life span extension.

Belongs to the ATG11 family.

135.025 kDa

MADADEYSTAPTQQEITPLQTTATIINAISGECITTNVDFFVSLDKFKQFIARKWKIPPDQLLILLPYGNKLKPSMFKELLINRSFTLNDFYVYDRRLFSLVSKPTPTNLLTSKDSNPMNSPNSNDLTETLEYLIKNSHISQYQGSDTIMIKPMPSPLEDADVDLSRLNYHSVTSLLTTNLGWLSALEIDVHYFKSLIPDIIAHIKRIFDGLTVCSQYLKLYCFDVESLYNSNVQFLNQLVDNGMTSKWEKCFNDTLSKLTALEGDSLQKFINIESLLENEKSVKILNHSINGKLNKIKREIDENASFRDIITVNIDRLRQMFTPNESKFELEDQMAESFEVLVSEMRTRSRNVLDKEEEEFNSQEFLKSMNVMLEKDKKESVKTLFTISQALYSQIGELIDLKKSLQKHAVAILGNIAFTQMEILGIKRLLLNECNKDLELYKKYEVEFAQVEDLPLIYGLYLIEKYRRLSWFQQILSFISNFNQDLELFKQNELRTRNKWVKNFGSIATVFCEDLLSSSDFKRLNEYHSHTSPPNEDEEDENENSIANYRQDLVKVSQAIDNYMTQIKETDVSEPIIDLLSKTLFETKRFHIIYSNFKNNNNNSSNGNSISPEGSIALKSDDVVKGYKTRIKKLESLLHEFQYSDIGHWPQGVLNTHLKPFRGSATSINKKKFLGASVLLEPANISEVNIDSVSQANNHQIQELESNVDDLLHQLQLLKEENNRKSMQISEMGKKISDLEVEKTAYRETLTNLNQELARLTNEEQSHRTEIFTLNASFKKQLNDIISQDNEKIEKLTGDYDDVSKSRERLQMDLDESNKKHEQEVNLLKADIERLGKQIVTSEKSYAETNSSSMEKGEKFETIPLAEDPGRENQISAYTQTLQDRIFDIISTNIFILENIGLLLTFDNNNNIQIRRVKGLKKGTAQSNILDESTQMLDAHDNSLIKSPVFQKLKDEYELIKSVANGSEKDTQQSIFLGNITQLYDNKLYEVAVIRRFKDIETLAKKLTKENKIKRTLLERFQREKVTLRNFQIGDLALFLPTRENVNSVGSMSSSTSSLSSSFSSVDLSTPPPLDAMSIQSSPSVIHSNVINQASISGRDKNKLMRPWAAFTAFEESTRYFLKDEKGLTKGKEWFVGRIVTLEHFVADSPSNNPFRLPKGSVWFQVTAVVVSYQGV

ATG11

Autophagy-related protein 11

1165 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

135.262 kDa

MSEISYLSINNAHNGIIIKIPKPVRFHTLSEFKKYIQQSYSIDSVDNLFLLTTFGIKLNYNLINEIGEVFVYDKRLFTNIVDQSLIDQYTQSTFRVSEPTHSPLLKSNVGFLKQNLSSNLKINQGWARIITQDGELMDQYCRELIQQINVIFKCLNTIFQFATNFTNEIEKNFSNFFNYVKLINYKTLHKSWITNYKNLKTFPTFKIDNENIKLSDFLEVDRLQSSADYIEKFLPLIVNKLNELKQVIETVNEEKLTVDKFIETSRNESISNFKNVNISNVLSQLQTESQQLTDDIENLHYKNMDEIYRLHRDKLSISIYNNAKDIYKNLNDLQQFKNKLTKASLKAFNTIANLQMKMVGVKTEMKKITTEDETATEDSKVGDVNYKTISNVKKYEDYLSLTIDLPLIFGFSLIEKRRQFEWYDFYSKGIVNNVSEQLSTIIEHEKVFRGIWLKKFGTLLSLINDDPLTPSLPNIDVTLVGNRQNNFSILYDLKIERDDIINYISLIEATNMSKNFVTLLNKNFKDLIASTNNMKKVTKVISSLSTYTTNSADDKSKSSHEEGTEEEIDFDLNLIKGLKSRIKKLENLLHQQQFKNLNNWPVIRNVPSMTNDNRQSTIIQPTVVSPARTNPTQLLSRNPSTTKENTTTNIHNNHQQSEVLDSSVIDKHLDNIRLKKLNNELQTKNTELTNQINSKNETITQQQKEMEHMKLKTEKRVDELMKKLQEKDEECQSLKQENKIKCDEVENLTKKLELSDNHNKELEAKITEYTQKATSKTKEIADLNKTVSNLRSELGDAMHMKNDLLSNLSSKEAEFTKERNQFNNDLKALQLKLDEINEDYENLMELTQAKQKKHDLIINDLNNVIINLMNDIKKTLLSVFEYFLEYCLVLESMGLLLVKEDEIYKIKRVKGLKSKKSIGDGDMSIISNGTPSSKVIEEIENEINIVNNIPPISSILPDSYSSGTESDSVVDRYNDQSMKLISTFNQLFKFNNENENENRIDHILNTLAFKNNVQLQEDSINDTRFFLNAISKRFRDVEGFAKRQAKDNKLKEQEHRKLVHRLNSKISVNGFQEKDLVLFLPTRIDRPNGENIPSNDKIQPWAAFNIGAPHYFLKTEQTKNKEWIIGRVKKITEYKVTEENVQSLESNPFQLSVNVTWYLVEADEE

ATG11

Autophagy-related protein 11

1162 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

133.41 kDa

MTDLSYLIIYNAHTGTSSRIPKPIRYHSLGDFKRFLQTQLHVDSIDNLFLLTSFGIKLNFGLINELNEVYVFDKRLFGNSYDPEVLSQYTAESFEVVKPTPSTALASTETQIRIISSSLKSNQGWARAIVQDCHHTEELAKELVRNINAIFKSLNTIFQFATNFINEIEKNFNSYLNYIKLINYKTLHRTWIDSYNILKQYPPFKIKDASVFLVDFLNHDKLLEAANYVSSNLPLVVSKFNGMSETINSVGEEKLTVDKEIESLRNGSINEFKDVNLSELMAKIYSLSRSITNDLEQVSNNDSIKLDEVYKEHKENYSPLLYDNAVELHNYFLGLRKFKEKLTKQSVSIFNSIANLQMKMVSIKSNLKTLTTPSESTDPISFETINTIKKYEDYLSLNIDLPLLFGFVLIEKRRQFEWYDFYSKGIVNNVSEQLSTIIDHEKLFRKIWLRKFGNFLTLLSDETPTTSLPNIDVTLVGIKEETFKILHDIQVERSDIVNYIAFVESSKASKNFVELLNKNFRDLIRSTNNMKKITRVISSLGTYTSLSGEEKSKILSKEDEEGEIDFDLNLIKGLKTRIKKLESLLHQQQYKNLTSWPVTRNNVAPSSSDNRLSLIIEPQKKTVTPPKSDPKQLLQKQSVPTRTSSAQSAVLDSTNIDIRLELIKIKKENTELINENSALHQSNDESQKLIKDLRKEIEELKAINASHRQEADAKLLMKEEEFRLFKLDNKVDTKLVENLEKKVEQRDAQVSKLKEDLSRVMEINTTSDKEIIALNSTISSMRNELNDTVVMKNDLLSNISAKEVEHSKERNGLENEIKTLSAKVDELTEDYENLMEITQSRQKNADLLVNDLNNIIIKLMNDMKRLAENIFEYFLEFCFVLESMGLLLTMDGDVYKITRVKGLRSKKTVDDPNDTSFISIEKPSSKVIDEVDKSMSWVTTISNLSSILPEVPGTSSTASENGHESNEEESNKFNSQSLKLITIFNEIFTANNAKFEDFLRIISFQENVQLQEDSAHNSKFFLNAISKRFRDVEGFAKRQTKENKIKEQEIHKLVGRLATKISMNGFQIGDLVLFLPTRIDRAVEVANESIQPWAAFNIGAPHYFLKVDDEERTKNKEWMVGRVESIEENKVTDENAGDLSSNPFQLSVGVVWYLVEAKEEHF

ATG11

Autophagy-related protein 11

1148 amino acids

Accessory protein involved in autophagy. Acts as scaffold protein of the ATG1-ATG13 complex for faithful delivery of autophagic vesicles to the vacuole. Involved in the stress-induced phosphorylation of ATG1A for turnover of ATG1-ATG13 complex and proper ATG1-ATG13 complex assembly or activity. Required for selective mitophagy. Required for senescence-induced breakdown of mitochondria-resident proteins and mitochondrial vesicles. Seems not essential for ATG8-mediated autophagy.

Belongs to the ATG11 family.

129.184 kDa

MSGSFTESFADDGKLLLCVAENGHSFEFQCSETTSVESVMRFVESVSGIALSDQLLLSLDMKLEPQKLLSAFGLPASDREVFVFNKAMLQSNSHPPSPEDVDLQDVADALPPASLHEHHPLDDASDPALKALPLYERQFRYHFHKGRTIYNCTVVKHENCERLTREQKVQQRAVEVATRNLEQYYRVIYQNFLEFMKRYKHQHRLHSDLLMNFGRDIEKLRSAKIHPYLQTESRKCLLDFVKEDNLKKAVENCASSHRQFENKIAQFQQMFVEVKRKVEELFACRASLSMKNLEVTVKDHERFIDEEKSIMQSLSKDVNTVKKLVDDCMSSQVSSSLRPHDAVSALGPMYEVHDKNHLPKMQACYNSISELLDFCKNKKNEMNNFVHGYMQKITYVTYIIKDAKLQFPVFREAMVRQDDLFADLKLVRGVGPAYRACLAEVVRRKASMKLYMGMAGQLAEKLAMKRETEVRKREEFLKTHGPFVPRDVLASMGLYDTPTQCDVNVAPYDTSLLNIEISDVDRYAPEFLVGLHSKIASLKSSLTMSGDSSLSAEPEEIGIDTFDKDNFDDILAASELIEIAGTSKMEVENAKLKADLASAISRICSLGPQFEYEVLDESEVENVLKNAADKTAEALQAKDEYEKHLLLMLKEKQMHCDSYEKRIRELEQRLSDEYLQGQRHNNKDVSGLNLMHEKVSEYKAEASSDVEGNKTHVSGSEPMDEVSCVSNLTSKQPCKAREGMDENMVDSSQVLSQPLDSSMLESQQNNEKGGKDSEAGEMGVFLSNSSTAESPQKSLDDNVATGRGLDAKDSGDIILELRNELMEKSNKLSEMESKLNGAMEEVSNLSRELETNQKLLEESQMNCAHLENCLHEAREEAQTHLCAADRRASQYTALRASAVKMRGLFERFRSSVCAGSGIADFADSLRTLAQALANSVNENEDDGTTEFRKCIRVLADKVSFLSKHREELLEKCQNLEATSEQTRKDLEEKKELVKTLYTKHQLGKQANKEKISFGRLEVHEIAAFVLNQAGHYEAINRNCPNYYLSSESEALFTDHLPSRPTYIVGQIVHIERQIVKLPSQLSASASPEAGKTHHLCSDQGSRTLASSSISTSTSATTTSNPYGLSSGCEYFIVTIAMLPDTAIHQQAS

ATG11

Autophagy-related protein 11

1110 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity). Contributes through its regulation of pexophagy to survival during engulfment by host phagocytic cells during infection. Through its function in autophagy, acts as an important virulence factor that supports the viability of C.glabrata in the phagosomal compartment of infected innate immune cells.

Belongs to the ATG11 family.

127.649 kDa

MEYRCLDCTTGDTIAVDLKVFLDLKEFKSYLSNKWGVPRAQILLLYPFGIKLKDSNFRHASDLESPEIYVYDRRLFSLTNEPHTGADAHADSDADADADTADVEQQAAQLLDSLLEQRRHPQLQDDLIRPIPSPLEDLKIADGISHRTAVSMLTTNLGWLSALEIDVNYYSSISDKCKEDTQSLARCLGTCEQYLGLYCYDVERLYNSNVVFLDQLHENSLQSRWKECYKNTLTKLAGLNGYLSQYVDEAKQIEKEVTLKSLDGKVNSKLKQIKKELDSYADQRKSIQNEIENLKNIKDMKNDDNELHEMQKSFDSIADTVRKASRDILDKDDALFTDEYITQEVVPVMIDIQKKVKTLLTVSQALYENMHELLTHKRNFQIQIIVKLGQIAWIQLQISELKQYLLNDCNADLTLYKDLEVEFAQIEDYPLIYGLYLVEKYRRQVWKCGMAKNMISISNDIKERSAAELTTRKNWYKNFGELSKPFNEDLTKYNDLDEISKLMNSDSQFLKEKFIQDLRNEQRKLEDVIKSFIKNMHDLGLSKETTQVLEQSFKEASNSNICSQIDVTYDHRRINNENDLIKRYKIRIRKLESLLHEQGYSSISKWPSGVLNHTDRPNYFADNVSPAGRSLLVSSSALLGLEPSASLKTDAEMFDLKKEIGDLSEKVTALEKDNKLKTDQLKITHSKLIDIEVEKAAFRETLNHLNKELARLTVNEEDQTNLLKEERLRFKKEMTSVTVVNQNLMNNLDALQKTFEDVELENAHLKSKLKELQQRQDQLIEDSANEKLEIKSKYEKLIKEKDENMGQAFAVTNKAISGEQNKTESDIIHSSPYPEAILHLRTELFDIFSTNIYILENIGLLLTETSAGKFEIKRVKGLKKGLSQSLLDESAQISPIDGVINSVVYKNIRAQYEQLPNDNNISNCELFISSVKKIYENKLFESAVINRFKDIETLAKRLTKENKSKRILIDLYQNERLAVKDFRVNDLALFLPTKEALSETKSLSSSMASSFSSVDLSTPISGANNNITASRKSLHKPNVKHPWAAFTAFNESSRYFLKDENMVTDNKEWFIGKITDIQRQVVENISTNNPFKLPKDTVWYLISAEMISID

ATG11

Autophagy-related protein 11

1084 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy (PubMed:26442587). Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32 (By similarity). Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation (By similarity). Required for ATG9 anterograde transport from the mitochondria to the PAS (By similarity). Recruits also the ATG19-prAPE1 complex to the PAS (By similarity). Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

124.697 kDa

MPPCELISASNGASFQLSDLYFPSFLDLKQFVGETFHISVDDILLLLSYGIILKRSQWDSTKIRSEGLKSIYVFDRKLFNEDIELAVEERFRLFKPLDSPMSDLSEVDRNIVLRNMGWLKALQSDVEFFQLSIEQTRKEVQNMLDCGVVMLEYLKNYCHEVETLYNSHVGFLNKLHEHSASSQWREVYDSVLEAVKIDQQRSLASFFQIDELNQIEAKIRHTDHELNMKLKELKKTIDTCYQHRKTLVSELENIKSISVVSPDCMDKQMTDKFNEMAQELEAASNEWVQNSENNDHISEKVKQMKDSHIPNLQTISQSLFNKASKIIETKTDMQRQLRSLYISVAKSQMDIIEVKSTLTKDMKSDMKLLQTYELQLSQVLDLPMCYGLYLIELYRQQLWMDNYTHIKDQHESALQVMLQEEIHQRKMWYRDFQWISKFLKVDQSLPSTVSITPLKALRRVDLLQINEYFNQLSSAKVSETTLNVLKSKLSQAEMDNMLPELSEQSSNDTGAAIEGYKSRIKKLENLLLDAQFQRYDSWPSGILNKEIAMVQMFRNNTLNNKVQRSSTDDISNSIQQSYSKTLGDVQNLQKAISEYSGLTDTLKEELSTLKSQISNMEVEKNAYKESMANLNKELSNLLINRENFHTEMMERSNDFKKHLALVGEENEQLTKQNQQLSNEIIESQKKYEELNKIKDDLLLNMANQETQAEQERAALQEEIESLKKEVGQLQMAKSSLTESEELLGINKQLEKTLYDVFQGSIFLLESIGLLLSKDIDGKFQIVRVKGLRKDLDSSVIDMNGSLVKSVVSHEIKDTFESIKDSLDYKPHENFISYTEKLFGNQLFEMAVIRRFNDIESLAKKLRKENKNKKILLQKYTNDKITINNFQLGDLALFLPINDQELLLNSSVSSLNSSFSSIDLNSSTQSMIPPRVIPNRVEPASNTNNSNPSSVPEDMGSPNMNRVNTMGNVKVNANIGSNNSNNNYVNTGNANGNNKPETNIDTTSSTNAESPKKQIVWAIFTATNTEVKYILRNTMSNYELLREKEWAVGRITALEKNIVMEGARNPFKFPQNTVWFEVDALFNLS

ATG11

Autophagy-related protein 11

1083 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

124.171 kDa

MHLTIHNAHNGLTTSIQKPIRYHSYQSFKEYIVESFTNYILDDANNVFLLTQFGMRVDFNIINELNDIYFFDKRLFVNENPASILKDYATQTMRDIPPPKHPSLAPYSRGLNIRQMSSSLRSNAGWSMSVKVDAALADEQVRAYKRQISVMFRCLSIMFEFIASFTSDIENSFTKFYNHINQLSLKTLHEHWKSHYKTLASRPQFTFKNGKSVRLADMLNYDALVEASQFVERNLSTVIDQFNQLSATINEVNKSKIDIDGEIQVLRDESIAEFASLKASESLVEDIKSIGTAISTEIDSIASSESRVLGDIYTKHVESSKKLDEKYVQLYNDLTKLDQFKDKLAEKGTALFRHCARLQMQMVNVKLALNEFDSRKQEGKQRSAMQKVQEIKKKEEYLSLTIDLPLLFGFAIIEMRRQYEWYDFFASGAVSNVTEQLQVIINQERVFRKIWAKKIGSFLSILDSLPSDLSQTLPSLDVTVVKGREDFFGKFWIHDIQREDIDKYIKWVGSIDAGKHANFSMLLERNFEDLIKSTNAMKSVTKAIGTLSSYTSPENIDAVQPNDKKEDQDLIQGYKNRIRKLENLLHQQQFKDLSTWPVIKGATQDQSIIFNPKRNSGVGSDNVLVHSQHDAKILLQNHRSSIKDESSSRTDHLKLAKENEDLRKRLQELQIGGERRVEAKVPFEASLSGTKILAQQNTEILAQKKALEMKVDSQLQVIEKIQKESSEKDNEIFALKKQIQDLTGEANEFYARNEELKKNAEVKYDHLVQELNEEKDKSSSLSSELDAMKRGANDRKDAEKAIAELTSVASDLYGKLVDHSHITFDYVLTLSYILEKMGLMLTNEEGKNNVFKIRRVKGLRSRKQDGENSQTDVGSPVPGAIKNMMVWSHTDINVNPADMIESAKEIINVCRNKMDETFDKYNQVVAFRSNVSIEQVSEHDIRTIEFFSNAVVKRFKDVEGLAKKLAKEKKTYETQLQKLTRKMSAKVTLSNFQTNDLVLFLPTRLETKEPQEVIQPWTAFNIGTPHYFLKSQPSVEREWIVARIVSIVEHTVTATNKNDTSLNPYRLSEGITWFSVEAKEVSQ

ATG11

Autophagy-related protein 11

1072 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

121.907 kDa

MGHVEGNLQLVNAISGRSIGTHVQYFMTMEDLKRFVIQQWHIPGPEIFILQPYGGKFKRGHFQDMVSEAKKAVARGRVRETSVLYVFDRRLFDGGEEALAQATRHDSTTLVRPLVSPLEDAEAEVGERAAASLLTTNLGWLSALEIDVRYFHACIEGWVQQLANMKECLSVLLQYLELYSFDIEKLYHASAEAVDGVRQRCASNDWRQKNQELLETIDAVASRGKLVQFVDLEEMSEAEERLRELERLLSKKLSLFRGALDENHAIRQEIANHIKEVGTRYQDNISNYELEAQILGNFKDMVKKVKEDTRTILDLDTTKVSPDLMTSAVSLFKEMKSTAIPALYTVGLSLFTQASKCMETKASLQREMLVILADIAVAQVNIVDAKNSLLQQVNQDISALHTTEQQLLRVSELPVVYGLYLIELYRRQHWITGLDRYYSEHTKEIQSVLQRELVFREKWSSDFSSYSEIFQWQDDKPQLAKLFSNASPLEVGRPCIDIGTIQTYIEMLARCDVAEDSQTLLKKTLSEVSRFQFIVKSPLAGSVSKDSTDSMNEVIEGYKNRINKLELLLHSTQFSNTSSWPTGVLNSNSLNVFHNNIASINEKLLLSDYKSRDSIMSGKSNEKELQSQLVELQKQLEEAKNEAKRVQQQLKTTKTQLLNGEDERTAYKETLSILNAELSKLILNQEEQKQELVIAAKDFQEKLDVSMRQVNDLLKQVNFWKSKCGDLDKIKQDLLANMATKETDFNNRCTDYERNIVELQRQLSEKCDATNERSVTSTSADVPGETKEYIESLKEVNRRLEEDMFAVFAGNIVLLENIGLLLSRGPDNKLQIIRVKGLRKNIDDSIIKDSSPVINSHMVKSTVFQDVKNLFDELQLSQGVNDQLHFVSELERFYEEDLFQTSVIKRFTDVENLAKKLRKENKAKKSVIERHNKDKITFRDLKVGDLALFLPTRGVAGSLTSSVASSLASSFSSVDLSTPPPPLPTASQSLIKVTPHKPHRNKSTPWAVFTASELGVRYFLKDSEELVKGKDWFVGKIQSMEKYTVNGDSRNPFKLPEGMVWYEVVASCTKEL

ATG11

Autophagy-related protein 11

1046 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

120.702 kDa

MPPCKLICATSGVSHQLSNVYFPSFLDLKQFASDTFQIPLDDILLLLPYGMILKKAGWDSRKLQQEGLEEIYVFDRGIFNEEIEFSPKPRFQLFKPLPSPISDSLQLDKNVILRNLGWLKALQSDVEFFQDVIKETYQDVQRLLECGTVMLEYLKNYCYEVEVLYNGNVDFLNKLHEDGASNQWHSFYDNILGNIKVSNQLLSSFFNYSELTEIEDSIHRLDRELNAKLKELKKSIDECYQQRTQLISDLDDVKKNSVVSSDDMDNQMVERFKEMATEIELVSNQYKEEASKDASKEKFETFKSVHVPKLQTISQAMFNKASTNLDTKATVQQKLQQLYLSVAKSQMSVIMVKSVLTKDVKTNMKFLKNEELKLSQVLDLPMCYGLYLIELYREQLWTDRYSQLRQQHESSLQHLLDDEVRQRNSWYKDFQWITRFLDVDSLLPSSVYIPSISDHKQVTLSQIKDYINQLASLNLGEPTINLLKSKVSQAELTGLHLPTDYALSKDSELIIEGYKARIKKLEHLLLDAQFHQYDSWPAGILNKETAMVQMFRNSTVSTKLQQSSTFDLPSSKQQHESNKTFEEFQNLQKDISKYSELTKTLETELSTLKSQLSHMEVEKNAYRESMTNLNKELSTLLIERENFYSEMNSRSENFKKHLGSLFEQNEELVRESEESRRKSEDLNKMKEDLLVNMATQEVQAEQERASLQEEVESLKKDLNQLQISKSKTIDAEFINFNKQLEKTLYDVFQGSIFILASIGLLLSKDQDGNFQIVRVKGLRKDLDSSLADMNSSMAKSVIAQEIKSTFESIKDQIDYKPHENFITYIEKLFGNQLFETSVIRRFNDIESLAKKLRKENKNKKLLLQKSARDKITIYNFQPGDLALFLPINDQELLLNSSISSLNSSFSSIDLNSSTQSVMQRPNVVKSDIAASILNGSSASITENIPLSKANRNPALNANGRPDTFNVNTQDSAKKHVVWAIFTATNTDIKYVLRNSTSNYELLKDREWAMGRISALEKHVVGDDSKNPFKFPRNTVWYEVDAFFNLD

ATG11

Autophagy-related protein 11

924 amino acids

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity).

Belongs to the ATG11 family.

104.021 kDa

MSEIRVSCASSGVSVSAARDQFSSLPHLKAWIELEFSVSVSEQLLLTVAAEQVKMAHLGTQNELFVFDRSVVGGTVSNEHKYSAPKLKTLTPGTDPSQWALTVLTHCSRLVEETKRVTAEIATIKRATNVAITQMKQHSQNLDKNLLNVKEYSKELNQGITPLLSVDLAQLRDNTRAVKLVAPAVFGKKQFLNDWLDLQQLQSIVVEFKADFPSCMDKLQTLEQDLAQLSKDTQTLVNSTDVWIGGTNSDVLCNEAVGILRKLSELTSGDHVTNEAVKSVQNCQSQILDLHKALSKAKFQTVQHSQKVLQSISQLQSRSTKLKPKLTHIGSELTKYEEKRVQAMKQVDVEFVYGCVLVEMLRRTVWSQSGGENGSVKSEIGTRVAWKKQFQDTFPFVDILNEQEDLTIDTISTSSPSIVHNLVIARPVVTDYISQVSSKEVRNNLESLLGGVTGSAAATSSFPRSLFRNGSISGSLMAERAPISSATNADDKIRGYEARIRKLEDLLYKQRMSQDTSRWSVSPGTPSAGFAVVSPGQLSSEARGSSLSPEPTETREQVKAREKAEEEARKAEEERLARDKAAAEALQSKVDQLSQSLLHTENEKNDLMANLASMESDFSRERRCLVQEISELKLRVEELEEQVETAAETSIERHQRADQETEELEQRLKAMTLAQNTVDDENSRLKITLQDMSQRLYTGYKRNCVLLESLGLQAQKEYDADGSEVVSFDIHRVKGLRKKHRGKKGEKTEKDSESDSTDDFSALYWATKTTPDSFESSYRTFLARIFLDYDLYVEKVAKRFEDLEHLARKLQKEARNYRTMTQQLDDETRSKIALNRFKVGDLVLFLPTRDPSRQPQPWAAFNVGAPHFFLKQKPGRELKDRDWLVGRITGMEERVVNGGIGDREENPFDLGQGLRWWWLEAEEE