Protein
ATPase family AAA domain-containing protein 3
Organism
Xenopus tropicalis
Function
Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important role in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis (By similarity).
Similarity
Belongs to the AAA ATPase family.
Sequence
MSWLFGLNKGQQGPPSVPGFPEPPSPPGGSGDGGDKNKPKDKWSNFDPTGLERAAKAARELDQSRHAKEALNLAKVQEETLQLEQQSKIKEYEAAVEQLKNEQIRVQAEERRKTLNEETKQHQARAQYQDKLARQRYEDQLRQQQLQNEENLRRQEESVQKQEAMRKATVEHEMELRHKNEMLRIEAEARARAKVERENADIIRENIRLKAAEHRQTVLESIKTAGTVFGEGFRAFISDWDKVTATVAGLSLLAVGIYTAKNATGVAGRYIEARLGKPSLVRDTSRFTVAEAVKHPVKISKRLLSKIQDALEGVILSPKLEERVRDIAIATRNTKANKGLYRNILMYGPPGTGKTLFAKKLAMHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWAGTSKRGLLLFVDEADAFLRKRSTEKISEDLRATLNAFLYRTGEQSNKFMLVLASNQPEQFDWAINDRIDEIVHFDLPGLEERERLVRLYFDKYVLQPASEGKQRLKVAQFDYGKKCSDLAQLTEGMSGREISKLGVAWQAAAYASEDGILNEAMIDARVADAIRQHQQKMEWLKAEGKENAAKESGKNPLQPLLEGTPV