Protein
Ankyrin repeat and SOCS box protein 5
Organism
Oryctolagus cuniculus
Function
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis.
Similarity
Belongs to the ankyrin SOCS box (ASB) family.
Sequence
MSVLEESRPFAQQLFNVYFTILSLFCFKLFVKISLAILSHFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTIDHITPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSTSCTELLLEYGAKAQLESCLPSPTHEAASKGHHEFLDLLISWGIDVDQDIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLIEFGADINAKNTELLRPVDVATTSSMVERILLQHEATPSSLCQLCRLCIRNYIGRPRLHLIPQLQLPTLLQNFLQYR