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ARF1

Gene
ARF1
Protein
Auxin response factor 1
Organism
Oryza sativa subsp. japonica
Length
699 amino acids
Function
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Similarity
Belongs to the ARF family.
Mass
77.502 kDa
Sequence
MSSQGAGGGVGDPELFAELWRACAGPLVEVPQRDERVFYFLQGHLEQLQEPTDPALLAEQIKMFQVPYKILCKVVNVELKAETETDEVFAQITLQPDPDQENLPTLPDPPLPEQPRPVVHSFCKILTPSDTSTHGGFSVLRRHANECLPPLDMSMATPTQELITKDLHGSEWRFKHIYRGQPRRHLLTTGWSTFVTSKKLISGDAFVYLRSETGEQRVGVRRLVQKQSTMPASVISSQSMHLGVLASASHAIKTNSIFLVYYRPRLSQSQYIVSVNKYLAASKVGFNVGMRFKMSFEGEDVPVKKFSGTIVGEGDLSLQWSGSEWKSLKVQWDEVTNVNGPERVSPWEIETCDGTAPAINVPLQSATKNKRPREPSETIDLQSLEPAQEFWLSGMPQQHEKTGIGSSEPNCISGHQVVWPGEHPGYGAVSSSVCQNPLVLESWLKDFNSSNKGVSPTLSEISQKIFQVTSNEARIATWPARSAYQAEEPTSKLSSNTAACGYRTEEVAPNASKVVEGKKEPAMFRLFGVDLMKCTSISTTTDDKSSVGAGEASAKGTGSHEDSGQLSAFSKVTKEHIAADESPQEIQSHQNYTARTRIKVQMHGNAVGRAVDLANLDGYEQLMNELEEMFNIKDLKQKWKVAFTDDEGDTMEVGDDPWLEFCQMVRKIVLYPIEDEKKIEPHPKLLSSANPEQDQKTGF

Gene
ARF1
Protein
Auxin response factor 1
Organism
Arabidopsis thaliana
Length
665 amino acids
Function
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Acts as repressor of IAA2, IAA3 and IAA7.
Similarity
Belongs to the ARF family.
Mass
73.668 kDa
Sequence
MAASNHSSGKPGGVLSDALCRELWHACAGPLVTLPREGERVYYFPEGHMEQLEASMHQGLEQQMPSFNLPSKILCKVINIQRRAEPETDEVYAQITLLPELDQSEPTSPDAPVQEPEKCTVHSFCKTLTASDTSTHGGFSVLRRHADDCLPPLDMSQQPPWQELVATDLHNSEWHFRHIFRGQPRRHLLTTGWSVFVSSKKLVAGDAFIFLRGENEELRVGVRRHMRQQTNIPSSVISSHSMHIGVLATAAHAITTGTIFSVFYKPRTSRSEFIVSVNRYLEAKTQKLSVGMRFKMRFEGEEAPEKRFSGTIVGVQENKSSVWHDSEWRSLKVQWDEPSSVFRPERVSPWELEPLVANSTPSSQPQPPQRNKRPRPPGLPSPATGPSGPVTPDGVWKSPADTPSSVPLFSPPAKAATFGHGGNKSFGVSIGSAFWPTNADSAAESFASAFNNESTEKKQTNGNVCRLFGFELVENVNVDECFSAASVSGAVAVDQPVPSNEFDSGQQSEPLNINQSDIPSGSGDPEKSSLRSPQESQSRQIRSCTKVHMQGSAVGRAIDLTRSECYEDLFKKLEEMFDIKGELLESTKKWQVVYTDDEDDMMMVGDDPWNEFCGMVRKIFIYTPEEVKKLSPKNKLAVNARMQLKADAEENGNTEGRSSSMAGSR

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Brassica rapa subsp. pekinensis
Length
182 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.256 kDa
Sequence
MGILFTRMFSSVFGNKEARILVLGLDNAGKTTILYRLQMGEVVSTIPTIGFNVETVQYNNIKFQVWDLGGQTSIRPYWRCYFPNTQAVIYVVDSSDTDRIGVAKEEFHAILEEEELKGAVVLIFANKQDLPGALDDAAVTEALELHKIKSRQWAIFKTCAVKGEGLFEGLDWLSNTLKSGSG

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Locusta migratoria
Length
182 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.688 kDa
Sequence
MGNVFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLAEDELRDAVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLKNANR

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Arabidopsis thaliana
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; required for the sequence-specific vacuolar sorting route to the lytic vacuole, for the ER-to-Golgi transport and for the Golgi-derived transport to the plasma membrane (PubMed:24369434). Involved in the recruitment of COPI and GDAP1 to membranes. Required for recycling of PIN auxin transporters (e.g. PIN1 and PIN2) in a fungal toxin brefeldin A (BFA)-dependent manner. Involved in various auxin-dependent developmental processes (PubMed:24369434).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.609 kDa
Sequence
MGLSFGKLFSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNIASKA

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Bos taurus
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.697 kDa
Sequence
MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK

Gene
ARF1
Protein
ADP-ribosylation factor
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.528 kDa
Sequence
MGVSFSKLFSNLFGHKEMRILMVGLDGAGKTTVLYKLKLGEVVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFRNTEGIIFVVDSNDRSRIAEAREVLQRMLNEDEIRNAVLLVFANKQDLPEAMSAAEITEKLGLHSIRQRPWYIQATCATSGEGLYEGLEWLSTNLKNQA

Gene
ARF1
Protein
ADP-ribosylation factor
Organism
Zea mays
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.661 kDa
Sequence
MGLTFTKLFSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLNSLRQRHWYIQSTCATTGEGLYEGLDWLSSNIATKS

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Catharanthus roseus
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.753 kDa
Sequence
MGLSFTKLFSRLFAKKEMRILMVGLDAAGKTTILYQLKLGEIVTTIPTIGFNVETVEYQYISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKHGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNIANKA

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Chlamydomonas reinhardtii
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.703 kDa
Sequence
MGLRFTKALSRLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNLANKT

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Daucus carota
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.681 kDa
Sequence
MGLSFTKLFSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEIIDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNIASKS

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Homo sapiens
Length
181 amino acids
Function
(Microbial infection) Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.697 kDa
Sequence
MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Macaca fascicularis
Length
181 amino acids
Function
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD) (By similarity).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.697 kDa
Sequence
MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK

Gene
Arf1
Protein
ADP-ribosylation factor 1
Organism
Mus musculus
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking among different compartments (PubMed:11950392). Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.697 kDa
Sequence
MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Plasmodium falciparum (isolate 3D7)
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.912 kDa
Sequence
MGLYVSRLFNRLFQKKDVRILMVGLDAAGKTTILYKVKLGEVVTTIPTIGFNVETVEFRNISFTVWDVGGQDKIRPLWRHYYSNTDGLIFVVDSNDRERIDDAREELHRMINEEELKDAIILVFANKQDLPNAMSAAEVTEKLHLNTIRERNWFIQSTCATRGDGLYEGFDWLTTHLNNAK

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Plasmodium falciparum
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.912 kDa
Sequence
MGLYVSRLFNRLFQKKDVRILMVGLDAAGKTTILYKVKLGEVVTTIPTIGFNVETVEFRNISFTVWDVGGQDKIRPLWRHYYSNTDGLIFVVDSNDRERIDDAREELHRMINEEELKDAIILVFANKQDLPNAMSAAEVTEKLHLNTIRERNWFIQSTCATRGDGLYEGFDWLTTHLNNAK

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Plasmodium falciparum (isolate NF54)
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.84 kDa
Sequence
MGLYVSRLFNRLFQKKDVRILMVGLDAAGKTTILYKVKLGEVVTTIPTIGFNVETVEFRNISFTVWDVGGQDKIRPLWRHYYSNTDGLIFVVDSNDRERIDDAREGLHRMINEEELKDAIILVFANKQDLPNAMSAAEVTEKLHLNTIRERNWFIQSTCATRGDGLYEGFDWLTTHLNNAK

Gene
Arf1
Protein
ADP-ribosylation factor 1
Organism
Rattus norvegicus
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.697 kDa
Sequence
MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Salix bakko
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.579 kDa
Sequence
MGLSFTKLLGRLFSKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVGEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNISSKA

Gene
arf1
Protein
ADP-ribosylation factor 1
Organism
Xenopus laevis
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.715 kDa
Sequence
MGNMFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK

Gene
ARF1
Protein
ADP-ribosylation factor 1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
181 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Recruits polyadenylate-binding protein PAB1 to COPI vesicles, and this is required for correct localization of the asymmetrically distributed ASH1 mRNA.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.529 kDa
Sequence
MGLFASKLFSNLFGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNVETVQYKNISFTVWDVGGQDRIRSLWRHYYRNTEGVIFVVDSNDRSRIGEAREVMQRMLNEDELRNAAWLVFANKQDLPEAMSAAEITEKLGLHSIRNRPWFIQATCATSGEGLYEGLEWLSNSLKNST

Gene
arf1
Protein
ADP-ribosylation factor 1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
180 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.619 kDa
Sequence
MGLSISKLFQSLFGKREMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYRNISFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRERISEAHEELQRMLNEDELRDALLLVFANKQDLPNAMNAAEITDKLGLHSLRHRQWYIQATCATSGDGLYEGLEWLSTNLKNQ

Gene
ARF1
Protein
ADP-ribosylation factor
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
179 amino acids
Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Similarity
Belongs to the small GTPase superfamily. Arf family.
Mass
20.258 kDa
Sequence
MGLTISKLFASLLGRREMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRYYFQNTQGIIFVVDSNDRDRINEAREELQSMLNEDELKDAVLLVLANKQDLPNAMNAAEITEKMGLHSIRNRPWFIQATCATTGDGLYEGLEWLSNQVGK