Protein
Calnexin homolog ARB_00147
Organism
Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)
Function
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.
Similarity
Belongs to the calreticulin family.
Sequence
MRLNAQLASLLLSSIVLVGSAHGADEEPVAEKKEASSIERPTFVPTTIKAPFVEQFTDKWDSRWSVSHAKKEDAKSDEEWAYVGEWSVEEPTVFKGIEGDKGLVVKNPAAHHAISAKFPKKIDNKGKTLVVQYEVKLQNSLSCGGAYMKLLQENKKLHSEEFSNASPYVIMFGPDRCGATNKVHFIFKHKNPKTGEYEEKHLKAPPAIKVTKLTSLYTLIVNPDQTFQIRIDGEPLKNGTLLEDFTPPVNPPKEIDDEKDTKPADWVDEEKIPDPEAKKPEDWDEDAPFEIVDTEATKPADWLDDEPTTIPDPEAVKPEDWDDEEDGDWIAPTVPNPKCEEGSGCGKWEPPMIRNPAYKGKWSAPLIDNPAYKGVWAPRKIPNPNYFEDKTPSNFEPMGAIGFEIWTMQNDILFDNIYIGHSIEDAEKFKAETYDIKRPIEEAEEEASKPKLSPQIDDETDISFTQDPIGYVRAKIDRFISLAQDDPIAALQAVPEVGGAIGAILASLLIIIGMFGLSSPAPPAKSTGKTAEKTEKEKTTEAVTASGADSGQGEAKKRAAKSG