Protein
Apicidin F cluster transcription factor apf2
Organism
Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831)
Function
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of apicidin F (PubMed:23825955, PubMed:25058475). Binds to the eight-base-pair motif 5'-TGACGTGA-3' called the 'Api-box' that is found in all promoters of the apicidin F cluster except in the promoter region of apf2 itself (PubMed:25058475).
Similarity
Belongs to the bZIP family. Highly divergent.
Sequence
MSPPSQDWSTITDANERRKAQNRVAQRNYRSRQKLRVELAEAILYDMPSWRTAVGLKRKRWLETPQSVEDHDTNPDSATPKPSLSSQVIQYHEEGQLVQNPTDFSMSADADVTADVSSGGESSDLSLGVFTPGDDWMNAEIDWTAAMTLAGDTSASEPDLRHRAVGPGNDIHAQPPVSIPVQAASGQHRTLTAPTPAESMSLRTEPPETAVITVTSNREVPNLGDSNEGSRSISTTKQPSEFKTPVLTAIAKGKLDIARLLISSGANIDTRDMHGRTNLHYAVSRSDAKTVRSLLELGADLLMSDASGVTALHMAVGADDQDMVKLLLGWCEQQDRTASSTDHKTTLKQCINSRDGQNMTPLHLCVVMERMDMLKILLDYGADVNIGCD