AOX4

Aldehyde oxidase 4

1341 amino acids

Aldehyde oxidase able to catalyze the oxidation of retinaldehyde into retinoate. Acts as a negative modulator of the epidermal trophism. May be able to oxidize a wide variety of aldehydes into their corresponding carboxylates and to hydroxylate azaheterocycles (By similarity).

Belongs to the xanthine dehydrogenase family.

147.634 kDa

MPSLSGSDELIFFVNGKKVVVKKPDPEVTLLFYLRRELHLTGTKFACGEGGCGACTVMVSRYSASSKQIRHYPVTACLVPICSLHGAAVTTVEGVGSIRTRVHPVQERLAKCHGTQCGFCSPGMVMSIYTLLRNHPDPTPEQVTEALGGNLCRCTGYRPIVESGKTFCANPTVCQVKRPGRCCLEQEEEEAGSVHTREKMCTKLYDKDEFQPLDPSQEPIFPPELIRMAEDPNKRRLTFQGERTTWLAPATLPDLLELRAEFPQAPLIMGNTTVGPDIKFKGEFHPVFVSPLELPELCVLNSEGDGVTVGSGHSLAQLSDALQSIVSQQPSERTETCRALLNHLRTLAGVQIRSMATLGGHVATRATVSDLNPILAAGKTTIHLVSKEGERQIPLDGAFLEGSPRAGLRPGEIVLSVFIPYSSQWQFVSGLRQAQRQENAMAIVNAGMSVRLEDGSSTIRDLQVFYGGIGPTVLSASRTCGQLVGRQWDDQMLGEACRGILDELRLPPGAKGGQVEFRHTLMLSLLFKFYLRVQRALSKLDPQKFPDIPEEYTSALEEFPIGTPQGTQIFRCVDPHQPPQDPVGHPVMHQAGLKHATGEAAFVDDLPLVSQELFLAVVTSTRAHAKIISIDTGEALALPGVVAVITAEDVPGENNHQGEIFYAQREVVCVGQIVCTVAADTYAHAREAAQKVKVEYEDIEPRIITIEQALEHSSFLSPERKIEQGNVEQAFKHVDQVIEGEVHVEGQEHFYMETQTILAVPRAEDKEMVLHLGTQFPTHVQEFVATALNVPRNRIACHMRRAGGAFGGKVTKPALLGAVAAVAAKKTGRPIRFVLERGDDMLITAGRHPLLGRYKVGFMKSGLIKAVDLEFYINGGCTPDESQLVIEYVVLKSENAYYIPNFRCRGRACKTNLPSNTAFRGFGFPQATVVVEAYMTAVASHCDLLPEEVREMNMYKRPSQTAYRQRFDPEPLRRCWKDCLEHSSFHARKRAAEDFNRQSRWKKRGLAMIPMKYTIGVPVAYYHQAAALVHIYLDGSVLLTHGGCELGQGLHTKMMQVASRELGIPTSYIHLSETSTVTVPNAVFTAGSMGTDINGKAVQNACQTLMARLQPVIRRNPKGKWEEWIKKAFEESISLSATGYFRGFQTNMDWDKERGDAFPYYVYGAACAEVDVDCLSGAHKLLRADIFMDAAFSINPAVDIGQIEGAFVQGMGLYTTEELKYSPKGKLRSQGTNDYKIPTVTEIPEEFHVTLVHSRNPVAIYSSKGLGEAGMFLGSSVISAIWDAVAAARKERKGAESVPETLAVRSPATPEWIRMACVDQFTDMIPRDDPSTFTPWSICVS

Aox4

Aldehyde oxidase 4

1336 amino acids

Aldehyde oxidase able to catalyze the oxidation of retinaldehyde into retinoate. Is responsible for the major all-trans-retinaldehyde-metabolizing activity in the Harderian gland, and contributes a significant amount of the same activity in the skin. Is devoid of pyridoxal-oxidizing activity, in contrast to the other aldehyde oxidases. Acts as a negative modulator of the epidermal trophism. May be able to oxidize a wide variety of aldehydes into their corresponding carboxylates and to hydroxylate azaheterocycles.

Belongs to the xanthine dehydrogenase family.

148.279 kDa

MPSVSESDELIFFVNGKKVIEKNPDPEKNLLFYTRKVLNLTGTKYSCGTGGCGACTVMVSRYNPKTRKIHHYPATACLVPICWLHGAAITTVEGVGSIKKRVHPVQERLAKCHGTQCGFCSPGMVMSIYTLLRNHPEPTPDQITEALGGNLCRCTGYRPIVESGKTFSQKSTVCQMKGSGKCCMDPDEKCLESREKKMCTKLYNEDEFQPFDPSQEPIFPPELIRMAEDPNKRRLTFQGKRTTWIIPVTLNDLLELKASYPEAPLVMGNTTVGPGIKFNDEFYPVFISPLGVPELNLMDTTNNGVTIGAGYSLAQLKDTLDFLVSEQPKEKTKTFHALQKHLRTLAGPQIRNMATLGGHTASRPNFSDLNPILAAGNATINVVSREGKDRQLPLNGPFLEKLPEADLKPEEVILSIFIPYTAQWQFVSGLRLAQRQENAFAIVNAGMSVEFEEGTNTIKDLKMFFGSVAPTVVSASQTCKQLIGRQWDDQMLSDACQLVLQEIRIPPDAEGGMVEYRRTLIISLLFKFYLKVQRWLNEMDPQKFPDIPGKFVSALDDFPIETPQGIQMFQCVDPKQPQKDPVGHPIMHQSGIKHATGEAIFIDDMPPIDQELCLAVVTSTRAHAKITSLDVSEALACPGVVDVITAEDVPGENDHNGEILYAQSEVICVGQIICTVAADTYIHAKEAAKRVKIAYDDIEPTIITIEEALEHNSFLSPEKKIEQGNVDYAFKHVDQIVEGEIHVEGQEHFYMETQTILAIPQTEDKEMVLHLGTQFPTHVQEFVSAALNVPRSRIACHMKRAGGAFGGKVTKPALLGAVCAVAANKTGRPIRFILERSDDMLITAGRHPLLGKYKIGFMNNGEIRAADVEYYTNGGCTPDESELVIEFVVLKSENTYHIPNFRCRGRACKTNLPSNTAFRGFGFPQATVVVEAYIAAVASKCNLLPEEVREINMYKKTSKTAYKQTFNPEPLRRCWKECLEKSSFFARKKAAEEFNGNNYWKKRGLAVVPMKFSVAVPIAFYNQAAALVHIFLDGSVLLTHGGCELGQGLHTKMIQVASRELNVPKSYVHFSETSTTTVPNSAFTAGSMGADINGKAVQNACQILMDRLRPIIRKNPKGKWEEWIKMAFEESISLSATGYFKGYQTNMDWKKEEGDPYPYYVYGAACSEVEVDCLTGAHKLLRTDIFVDAAFSINPALDIGQVEGAFIQGMGFYTTEELKYSPKGVLYSRGPEDYKIPTITEIPEEFYVTLVHSRNPIAIYSSKGLGEAGMFLGSSVLFAIYDAVTTARKERGLSDIFPLNSPATPEVIRMACTDQFTEMIPRDDPSTFTPWSIHVS

Aox4

Aldehyde oxidase 4

1334 amino acids

Aldehyde oxidase able to catalyze the oxidation of retinaldehyde into retinoate. Acts as a negative modulator of the epidermal trophism. May be able to oxidize a wide variety of aldehydes into their corresponding carboxylates and to hydroxylate azaheterocycles (By similarity).

Belongs to the xanthine dehydrogenase family.

147.841 kDa

MPSSSDELIFFVNGKKVIEKNPVPEMNLLFYVRKVLHLTGTKYSCGGGGCGACTVMISRYNPESKKIYHYPATACLVPVCSLHGAAVTTVEGVGSIKRRIHPVQERLAKCHGTQCGFCSPGMVMSIYTLLRNHPEPTPDQITEALGGNLCRCTGYRPIVESGKTFSPESSVCQMKGSGKCCMDLDEGCSESTKERMCTKLYNEDEFQPLDPSQEPIFPPELIRMAEDPHKRRLTFQGERTIWIMPVTLNGLLELKASYPEAPLVMGNTAVGPGMKFNNEFHPVFISPLGLPELNLVDTANSGGVTIGARHSLAQMKDILHSLTLEQPKEKTKTHQALLKHLRTLAGPQIRNMATLGGHVVSRPDFSDLNPILAAGNATINVISKEGQRQIPLNGPFLERLPEASLKPEEVALSVFIPYSGQWQYVSGLRLAQRQENAFAIVNAGMSVEFEEGTNTIKDLQMLFGSVAPTVVSASQTCKQLIGRQWDDQMLSDACQLVLEEIRIPPDAEGGMVEYRRTLIISLLFKFYLKVRRWLSEMDPQKFPDIPEKFVSALDDLPIETPQGIQMFQCVDPNQPEQDPVGHPIMHQSGIKHATGEAKFVDDMPRINQELCLTVVTSTRAHAKITSIDVSEALAYPGVVDVITAEDVPGDNNHSGEIFYAQNEVICVGQIICTVAADTYIHAKEAAKRVKITYDDIEPAIITIEQALEHNSFLSSEKKIEQGNVDYAFKHVDHIIEGEIHVEGQEHFYMETQTILAIPQTEDKEMVLHVGTQFPTHVQEYVSAALKVPRNRIACQMKRTGGAFGGKVTKPALLGAVCAVAAHKTGRPIRFILDRSNDMLITAGRHPLLGKYKIGFMNNGKIKAADVEYYTNGGCTPDESEMVIEFIVLKSENAYHIPNFRCRGRACKTNLPSNTAFRGFGFPQATVVVEAYIAAVASKCNLLPEEIREINMYKQISKTAYKQTFNPEPLRRCWKECLQKSSFFARKQAAEEFNKNNYWKKKGLAVVPMKFSVAVPMAFYNQAAALVHIFLDGSVLLTHGGCELGQGLHTKMIQVASRELNIPKSYVHLVETSTVTVPNAVFTAGSMGADINGKAVQNACQTLLDRLQPIIKKNPKGKWEEWVKKAFEESISLSATGYFKGYQTNMDWEKEEGDPYPYYVYGAACSEVEVDCLTGAHKLLRTDIFMDAAFSINPALDIGQVEGAFIQGMGFYTIEELKYSPKGVLYSRGPDDYKIPTVTEIPEEFYVTMVRSRNPIAIYSSKGLGEAGMFLGSSVLFAIYDAVTTARKERGLSDIFPLNSPATPEVIRMACKDQFTDMIPRDDPSTFTPWSIHVS

AOX4

Ubiquinol oxidase 4, chloroplastic/chromoplastic

351 amino acids

Acts early in chloroplast biogenesis as a component of a redox chain responsible for phytoene desaturation. Prevents the generation of toxic oxygen radicals and photooxidation of the nascent photosynthetic apparatus. Involved in the differentiation of multiple plastid types, including chloroplasts, amyloplasts, and etioplasts. Might participate in the chloroplast respiratory chain.

Belongs to the alternative oxidase family.

40.574 kDa

MAAISGISSGTLTISRPLVTLRRSRAAVSYSSSHRLLHHLPLSSRRLLLRNNHRVQATILQDDEEKVVVEESFKAETSTGTEPLEEPNMSSSSTSAFETWIIKLEQGVNVFLTDSVIKILDTLYRDRTYARFFVLETIARVPYFAFMSVLHMYETFGWWRRADYLKVHFAESWNEMHHLLIMEELGGNSWWFDRFLAQHIATFYYFMTVFLYILSPRMAYHFSECVESHAYETYDKFLKASGEELKNMPAPDIAVKYYTGGDLYLFDEFQTSRTPNTRRPVIENLYDVFVNIRDDEAEHCKTMRACQTLGSLRSPHSILEDDDTEEESGCVVPEEAHCEGIVDCLKKSITS