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ANB1

Gene
ANB1
Protein
Eukaryotic translation initiation factor 5A
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
158 amino acids
Function
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity).
Similarity
Belongs to the eIF-5A family.
Mass
17.132 kDa
Sequence
MAEEDHTFETADAGAALTFPMQCSALRKNGHVVIKNRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLSPSTHNMEVPNVSRQEFQLLDIDDGYLSLMTADGDTKDDVKVPEGELGDKLQSEFDEGKDLIVTIISAMGEEAAISYKEAPKGSA

Gene
ANB1
Protein
Eukaryotic translation initiation factor 5A-2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
157 amino acids
Function
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Essential for polarized growth, a process necessary for G1/S transition. May mediate large range of effects of the polyamine spermidine in the cell (By similarity).
Similarity
Belongs to the eIF-5A family.
Mass
17.131 kDa
Sequence
MSDEEHTFENADAGASATYPMQCSALRKNGFVVIKGRPCKIVDMSTSKTGKHGHAKVHLVTLDIFTGKKLEDLSPSTHNLEVPFVKRSEYQLLDIDDGYLSLMTMDGETKDDVKAPEGELGDSMQAAFDEGKDLMVTIISAMGEEAAISFKEAPRSD