Protein
Alpha-amanitin proprotein 2
Organism
Galerina marginata (strain CBS 339.88)
Function
Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters (PubMed:22202811, PubMed:7642577, PubMed:8702941).
Similarity
Belongs to the MSDIN fungal toxin family.
Sequence
MFDTNSTRLPIWGIGCNPWTAEHVDQTLVSGNDIC