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ALPHA-SCS1

Gene
ALPHA-SCS1
Protein
Succinate--CoA ligase [ADP-forming] subunit alpha-1, mitochondrial
Organism
Trichomonas vaginalis
Length
309 amino acids
Function
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
Similarity
Belongs to the succinate/malate CoA ligase alpha subunit family.
Mass
32.408 kDa
Sequence
MLAGDFSRNLHKPLLFIDKDTKVVIQGIGNQGQFHSRLMRQYGTKVVGAVHPKKAGTIIAGLPIFKNMKEVVKRTDANASLIFVPAPGAAAACIEAAEAGMGLVVCITEHIPQHDMIKVKKVMKETGCQLIGPNCPGLIQPGTHTKLGIIPTNIFNNGKIGIVSRSGTLTYEAAYATTLAGLGQSTVVGIGGDPFAGQLHTDVVKRFAADPQTEGIILIGEIGGTSEEDAAEWIAKTKLTQEKPVVASIAGATAPPGKRMGHAGAIVSGGKGTAEGKYKALEAAGVRIARHPGNMGKFIFEEMKRMGKI