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ALDH1A1

Gene
ALDH1A1
Protein
Retinal dehydrogenase 1
Organism
Gallus gallus
Length
509 amino acids
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (By similarity).
Similarity
Belongs to the aldehyde dehydrogenase family.
Mass
55.809 kDa
Sequence
MKKQGSPSNPAPVLPALPEPLKDLKIKYTKIFINNEWHDSVSGKKFEVFNPANEEKICEVAEGDKADIDKAVKAARKAFELGSPWRTMDASERGRLLNKLADLVERDRLTLATMEAIDGGKLFSTAYLMDLGACIKTIRYCAGWADKIHGRTVPMDGNFFTFTRHEPVGVCGQIIPWNFPLVMFIWKIAPALCCGNTVVVKPAEQTPLSALYMGSLIKEAGFPPGVVNIVPGFGPTAGAAISHHMDIDKVSFTGSTEVGKLIKEAAGKTNLKRVTLELGGKSPNIIFADADLDEAAEFAHIGLFYHQGQCCIAGSRIFVEEPIYDEFVRRSIERAKKYTLGDPLLPGVQQGPQIDKEQFQKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKTIDEVIKRANNTTYGLAAAVFTKDIDKALTFASALQAGTVWVNCYSAFSAQCPFGGFKMSGNGRELGEYGLQEYTEVKTVTIKIPQKNS
Protein
Retinal dehydrogenase 1: ALDH1A1

Gene
ALDH1A1
Protein
Retinal dehydrogenase 1
Organism
Bos taurus
Length
501 amino acids
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal. May have a broader specificity and oxidize other aldehydes in vivo.
Similarity
Belongs to the aldehyde dehydrogenase family.
Mass
54.806 kDa
Sequence
MSSSAMPDVPAPLTNLQFKYTKIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLIERDHLLLATMEAMNGGKLFSNAYLMDLGGCIKTLRYCAGWADKIQGRTIPMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPALSCGNTVVVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKLIKEAAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTIKISQKNS
Protein
Retinal dehydrogenase 1: ALDH1A1

Gene
ALDH1A1
Protein
Retinal dehydrogenase 1
Organism
Equus caballus
Length
501 amino acids
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (By similarity).
Similarity
Belongs to the aldehyde dehydrogenase family.
Mass
54.875 kDa
Sequence
MSSSGTPDLPVLLTDLKFQYTKIFINNEWHDSVSGKKFPVFNPATEEKLCEVEEGDKEDVNKAVAAARQAFQIGSPWRTMDASERGRLLYKLADLVERDRLILATMESMNGGKLFSNAYLMDLGGCLKTLRYCAGWADKIQGRTIPSDGNFFTYTRHEPVGVCGQILPWNFPLLMFLWKIAPALSCGNTVVVKPAEQTPLSALHVATLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPFIVFADADLETALEVTHQALFYHQGQCCVAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVSDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTTYGLFAGSFTKDLDKAITVSAALQAGTVWVNCYGVVSAQCPFGGFKMSGNGREMGEYGFHEYTEVKTVTVKISQKNS
Protein
Retinal dehydrogenase 1: ALDH1A1

Gene
ALDH1A1
Protein
Retinal dehydrogenase 1
Organism
Homo sapiens
Length
501 amino acids
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (PubMed:19296407, PubMed:26373694, PubMed:25450233).
Similarity
Belongs to the aldehyde dehydrogenase family.
Mass
54.862 kDa
Sequence
MSSSGTPDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS
Protein
Retinal dehydrogenase 1: ALDH1A1

Gene
ALDH1A1
Protein
Retinal dehydrogenase 1
Organism
Macaca fascicularis
Length
501 amino acids
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (PubMed:12576512). May have a broader specificity and oxidize other aldehydes in vivo (By similarity).
Similarity
Belongs to the aldehyde dehydrogenase family.
Mass
54.736 kDa
Sequence
MSSSGTSDLPVLPTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGATQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTNDIDKAVTISSALQAGTVWVNCYGVVTAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS
Protein
Retinal dehydrogenase 1: ALDH1A1

Gene
ALDH1A1
Protein
Retinal dehydrogenase 1
Organism
Mesocricetus auratus
Length
501 amino acids
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (By similarity).
Similarity
Belongs to the aldehyde dehydrogenase family.
Mass
54.673 kDa
Sequence
MSSPAQPEVPAPLANLKIQYTKIFINNEWHDSVSGKKFPVINPATEEVICHVEEGDKADIDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLMERDRLLLATLEATNGGKVFASSYLFDLGGCIKALKYCAGWADKVHGQTIPSDGDIFTYTRREPIGVCGQIIPWNFPLLMFIWKIGPALGCGNTVIVKPAEQTPLTALYMASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDTAVEFAHYGVFYHQGQCCVAASRLFVEESIYDEFVRRSVERAKKYVLGNPLNSGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWGNKGYFVQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTSYGLAAGVFTKDLDKAITVSSALQAGVVWVNCYMMLSAQCPFGGFKMSGNGRELGEHGIYEYTELKTVAIKISQKNS
Protein
Retinal dehydrogenase 1: ALDH1A1

Gene
Aldh1a1
Protein
Retinal dehydrogenase 1
Organism
Mus musculus
Length
501 amino acids
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (By similarity).
Similarity
Belongs to the aldehyde dehydrogenase family.
Mass
54.468 kDa
Sequence
MSSPAQPAVPAPLADLKIQHTKIFINNEWHNSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATMEALNGGKVFANAYLSDLGGCIKALKYCAGWADKIHGQTIPSDGDIFTYTRREPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVKRSVERAKKYVLGNPLTPGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSVDDVIKRANNTTYGLAAGLFTKDLDKAITVSSALQAGVVWVNCYMMLSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS
Protein
Retinal dehydrogenase 1: Aldh1a1

Gene
Aldh1a1
Protein
Retinal dehydrogenase 1
Organism
Rattus norvegicus
Length
501 amino acids
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (PubMed:7832787). May have a broader specificity and oxidize other aldehydes in vivo (By similarity).
Similarity
Belongs to the aldehyde dehydrogenase family.
Mass
54.459 kDa
Sequence
MSSPAQPAVPAPLANLKIQHTKIFINNEWHDSVSGKKFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLMERDRLLLATIEAINGGKVFANAYLSDLGGSIKALKYCAGWADKIHGQTIPSDGDIFTFTRREPIGVCGQIIPWNFPLLMFIWKIGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVRKSVERAKKYVLGNPLTQGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWGNKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSIDDVIKRANNTTYGLAAGVFTKDLDRAITVSSALQAGVVWVNCYMILSAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAMKISQKNS
Protein
Retinal dehydrogenase 1: Aldh1a1

Gene
ALDH1A1
Protein
Retinal dehydrogenase 1
Organism
Ovis aries
Length
501 amino acids
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (PubMed:26373694).
Similarity
Belongs to the aldehyde dehydrogenase family.
Mass
54.825 kDa
Sequence
MSSSAMPDVPAPLTNLQFKYTKIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLNKLADLIERDRLLLATMEAMNGGKLFSNAYLMDLGGCIKTLRYCAGWADKIQGRTIPMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPALSCGNTVVVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKLIKEAAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTIKISQKNS
Protein
Retinal dehydrogenase 1: ALDH1A1

Gene
ALDH1A1
Protein
Retinal dehydrogenase 1
Organism
Oryctolagus cuniculus
Length
496 amino acids
Function
Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (PubMed:12941160).
Similarity
Belongs to the aldehyde dehydrogenase family.
Mass
54.341 kDa
Sequence
MADLPTPLTNLKIQYTKIFINNEWHDSVSGKKFPVLNPATEEQICLIEEGDKADVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESLNAGKLFPNAYLMDLGGCIKTLRYCAGWADKIQGRTMPMDGDFFCYTRHEPVGVCGQIIPWNFPLVMLIWKIGPALSCGNTVIVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAASRLFVEESIYDEFVRRSVERAKKYVLGNPLAPEVNQGPQIDKEQYNKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTTYGLSAGIFTKDLDKAVTVSSALQAGTVWVNCYSVVSAQVPFGGFKMSGNGRELGEYGLQQYTEVKTVTVKISQKNS
Protein
Retinal dehydrogenase 1: ALDH1A1