AKR1E2

Gene

AKR1E2

Protein

1,5-anhydro-D-fructose reductase

Organism

Homo sapiens

Length

320 amino acids

Function

Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro) (PubMed:12604216, PubMed:15118078).

Similarity

Belongs to the aldo/keto reductase family.

Mass

36.589 kDa

Sequence

MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHKDYPFHIEY

Protein

1,5-anhydro-D-fructose reductase: AKR1E2

Gene

AKR1E2

Protein

1,5-anhydro-D-fructose reductase

Organism

Macaca fascicularis

Length

320 amino acids

Function

Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol.

Similarity

Belongs to the aldo/keto reductase family.

Mass

36.418 kDa

Sequence

MGDIPAVGLSCWKASPGKVTEAVKVAIDAGYRHFNCAYFYHNEKEVGAGIRYKIKEGAVRREDLFIASKLWCTCHKKSLVKTACRRSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPGVHDLPLDESDMVIPGDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPVTNQIECHPYLTQKNLISFCQSRGVSVTAYRPLGGSCEGVDLIDDPVIQRIAKEHSKSPAQILIRFQTQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLDRNLRLATFPITKNHKDYPFHIEY

Protein

1,5-anhydro-D-fructose reductase: AKR1E2

Gene

Akr1e2

Protein

1,5-anhydro-D-fructose reductase

Organism

Mus musculus

Length

301 amino acids

Function

Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol.

Similarity

Belongs to the aldo/keto reductase family.

Mass

34.461 kDa

Sequence

MENIPTVGLGTWKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKREDLFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFKPGEKDIPLDRNGKVIPSHTSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHKRNVSVTAYRPLGGSGGGFHLMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVTPSRIRENIQVFDFELTEKDMEELLSLDKNLRLATFPTTENHQDYPFHIEY

Protein

1,5-anhydro-D-fructose reductase: Akr1e2

Gene

AKR1E2

Protein

1,5-anhydro-D-fructose reductase

Organism

Sus scrofa

Length

301 amino acids

Function

Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol.

Similarity

Belongs to the aldo/keto reductase family.

Mass

34.107 kDa

Sequence

MEKIPVLGLGTWQAAPGEVTEAVKVAIDTGYRHFDCAYLYHNENEVGVGIQAKIDEGVVRREDLFIVSKLWCTCHKKSLVKSACTRSLKALKLQYLDLYLIHWPMGFKPGEVDLPVDRSGMIVASNTDFLDTWEAMEDLVIEGLVRAIGVSNFNHEQLERLLNKPNLRVKPVTNQIECHPYLTQKKLISFCQSRNVSVTAYRPLGGSSEGVPLLEDPVIQTIAQKHGKSAAQILIRFQIQRNVIVIPKSVNPKRILENFQVFDFELSEQDMTDLLGLDRNLRLSAFPIAENHKDYPFKAEY

Protein

1,5-anhydro-D-fructose reductase: AKR1E2

Gene

Akr1e2

Protein

1,5-anhydro-D-fructose reductase

Organism

Rattus norvegicus

Length

301 amino acids

Function

Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol.

Similarity

Belongs to the aldo/keto reductase family.

Mass

34.5 kDa

Sequence

MHQIPTVGLGTWKASPGEVTDAVKVAINLGYRHFDCAYLYHNESEVGMGIKEKIKEGVVKRDELFIVSKLWCTYHKQSLVKTACINTLEALNLDYLDLYLIHWPMGFKPGDKDIPLDRSGKVIPSHTSFLDTWEAMEDLVIEGLVKNIGVSNFNHEQLDRLLNKPGLRIKPITNQIECHPYLNQKSLIDFCHGRNVSVTAYRPLGGSRDGVHLMDDIVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVNPSRIRENIQVFDFELTEKDMEELLSLDKNLRLATFPSTENHKDYPFHIEY

Protein

1,5-anhydro-D-fructose reductase: Akr1e2