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AK2

Gene
AK2
Protein
Aspartokinase 2, chloroplastic
Organism
Arabidopsis thaliana
Length
544 amino acids
Function
Involved in the first step of essential amino acids lysine, threonine, methionine and isoleucine synthesis via the aspartate-family pathway.
Similarity
Belongs to the aspartokinase family.
Mass
59.605 kDa
Sequence
MASLQLYGVKTPGLALSSKRLEFASKGACFSVTLPSSSAVFRDVEHSCRNIGLRVSCEALRVDLLQRKEPETCDSSGTGKELTCVMKFGGSSVESAERMKEVANLILSFPDERPVIVLSAMGKTTNKLLKAGEKAVTCGVTNVESIEELSFIKELHLRTAHELGVETTVIEKHLEGLHQLLKGISMMKELTLRTRDYLVSFGECMSTRLFSAYLNKIGHKARQYDAFEIGFITTDDFTNADILEATYPAVSKTLVGDWSKENAVPVVTGYLGKGWRSCAITTLGRGGSDLTATTIGKALGLREIQVWKDVDGVLTCDPNIYPGAQSVPYLTFDEAAELAYFGAQVLHPLSMRPARDGDIPVRVKNSYNPTAPGTVITRSRDMSKAVLTSIVLKRNVTMLDIASTRMLGQYGFLAKVFTTFEDLGISVDVVATSEVSISLTLDPAKLWGRELIQRVNELDNLVEELEKIAVVKLLQRRSIISLIGNVQKSSLILEKVFQVFRSNGVNVQMISQGASKVNISLIVNDEEAEQCVRALHSAFFETDP

Gene
AK2
Protein
Adenylate kinase 2, mitochondrial
Organism
Bos taurus
Length
241 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
26.497 kDa
Sequence
MAPNVPAAEPVPESPKGVRAVLLGPPGAGKGTQAPKLAKNFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVLELIEKNLETPPCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPQSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNKKALKIRLEAYHTQTTPLVEYYSKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI

Gene
ak2
Protein
Adenylate kinase 2, mitochondrial
Organism
Danio rerio
Length
241 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
26.616 kDa
Sequence
MAPSTQEDDTVSGIRKGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGQRLKETMDAGKLVSDEMVVELIDNNLDTPACKNGFLLDGFPRTVKQAEMLDDLMEKRSEKLDSVIEFSVDDSLLVRRICGRLIHQPSGRSYHEEFHPPKEHMKDDVTGEPLIRRSDDNETTLRSRLESYHRQTSPLVQYYSARGLHTAIDASQSTDLVFASILAAFSAATCKDLVYFV

Gene
ak2
Protein
Adenylate kinase 2, mitochondrial
Organism
Xenopus laevis
Length
241 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
26.527 kDa
Sequence
MAPREAAPAERGSMMEGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGKRLKATMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDELLEKRQEKLDSVIEFKVDDSLLVRRICGRLIHASSGRSYHEEFNPPKEPMKDDVTGEALIRRSDDNESTLKSRLEAYHTMTSPLVDYYQRHGIHTAVDAAQSPDVVFASILAAFSKAHCKDLVLFV

Gene
ak2
Protein
Adenylate kinase 2, mitochondrial
Organism
Xenopus tropicalis
Length
241 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
26.563 kDa
Sequence
MAPREAAPAERGSVMEGIRAILLGPPGAGKGTQAPKLAEKYCVCHLATGDMLRAMVASGSELGMRLKATMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDELLEKRQEKLDSVIEFKVDDSLLVRRICGRLIHASSGRSYHEEFNPPKEAMKDDVTGEPLMRRSDDNETTLKSRLEAYHTMTSPLVEYYQRHGIHTAVDAAQSPDVVFASILAAFSKARCKDLVLFV

Gene
AK2
Protein
Adenylate kinase 2, mitochondrial
Organism
Homo sapiens
Length
239 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
26.478 kDa
Sequence
MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI

Gene
Ak2
Protein
Adenylate kinase 2, mitochondrial
Organism
Mus musculus
Length
239 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
26.469 kDa
Sequence
MAPNVLASEPEIPKGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDIVFASILAAFSKATCKDLVMFI

Gene
AK2
Protein
Adenylate kinase 2, mitochondrial
Organism
Homo sapiens
Length
239 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
26.478 kDa
Sequence
MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI

Gene
Ak2
Protein
Adenylate kinase 2, mitochondrial
Organism
Mus musculus
Length
239 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
26.469 kDa
Sequence
MAPNVLASEPEIPKGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDIVFASILAAFSKATCKDLVMFI

Gene
AK2
Protein
Adenylate kinase 2, mitochondrial
Organism
Pongo abelii
Length
239 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
26.478 kDa
Sequence
MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI

Gene
Ak2
Protein
Adenylate kinase 2, mitochondrial
Organism
Rattus norvegicus
Length
239 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
26.379 kDa
Sequence
MAPNALAPEPEHPEGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVKQAEMLDDLMDKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDVVFASILAAFSKATCKDLVMFV

Gene
ak2
Protein
Adenylate kinase 2, mitochondrial
Organism
Salmo salar
Length
238 amino acids
Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
Similarity
Belongs to the adenylate kinase family. AK2 subfamily.
Mass
25.885 kDa
Sequence
MAPSTQRNEAVSDVKKGIRAILLGPPGAGKGTQAPRLAEQYCVCHLATGDMLRAMVASGSGLGKRLKETMDAGKLVSDEMVVELIEKNLDTPPCKKGFLLDGFPRTVKQAEMLDDLLEKRTEKLDSVIEFSVDDSLLVRRICGRLIHQPSGRSYHEEFNPPKEPMKDDVTGEPLMRRSDDNASTLRSRLEAYHGQTVPLVKYYSARGLHKAVDAGQSPDVVFASILAAFSSATAATSV