Protein
Apoptosis-inducing factor 2
Organism
Taeniopygia guttata
Function
Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest (By similarity).
Similarity
Belongs to the FAD-dependent oxidoreductase family.
Sequence
MGSRLSLDGSVRVVVVGGGFGGTAAASLLKSWAVPFVLVDVRDAFHHNVAALRAAVESGFAKKTFISYSVTFGDSFRQGKVVAIDPGRQQVVLSDGEELHYSHLILATGSDGPFPGKFNQVIDMESAIQTYEDMVKEIEKSQRILVVGGGAAGVEMAAEIKTEYPGKEIILIHSKTALADVELLPSVRQVVKEILLRKGVRLLLSEKVSDIENLRPNQFQKDMVVRTEKGTEVVVDMVVLCTGIKINSSAYAAAFGDKMASDGALKVNKHLQLEGYENIYAIGDCADLKEPKMAYHAGLHANVVVTNIINSLTQKPLKTYEPGSLTFLLSMGRNDGVGQVNGYYVGRLLVTIAKSRDLFVSKSWRTMGQTMPS