AHRR

Aryl hydrocarbon receptor repressor

701 amino acids

Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

76.265 kDa

MPRTMIPPGECTYAGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLEGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQPPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRADTAATADAKVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQTDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDREEEQHRMLSRASGVTGRRETPGPTKPLPWTAGKHSEDGARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNSPISHPPSPSPSAYSSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMPPGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRSHPATFPTRMHLKTEPDSRQQVYISHLGHGVRGAQPHGRATAGRSRELTPFHPAHCACLEPTDGLPQSEPPHQLCARGRGEQSCTCRAAEAAPVVKREPLDSPQWATHSQGMVPGMLPKSALATLVPPQASGCTFLP

Ahrr

Aryl hydrocarbon receptor repressor

701 amino acids

Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

77.726 kDa

MMIPSGECTYAGRKRRKPIQKRRLTMGAEKSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSYLRVKSFFQALQETCVWSAPALSPEEHSYRGFPVQEGRLLLESLNGFALVVSAEGMIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADTDNTVLGKLLRAQEGGKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPSGTALPPRLSLFCIVAPVLPSVTEMKMKSTFLKAKHRADIVVTMDSRAKAVTSLCESELHPKLNYLAGKSNGENGISLFRGQTDRSHWARALARSSCLCLRGGPDLLDPKGTSGDREEEDQKHILRRSPGAWGQREMHKYSYGLETPVHLRHLNWSTEQRSQESTTKLTRQPSKNEPSTCLVPHGSCVPYPGSQGMLSASNMASFRDSLDHPTGAYCSQMNRPLSDIHQGQVDPSTCHISQGSLGSRIPLTGMQRFTARGFSTEDAKLPSLPVTIGTPCNPVLSLDVPIKMENESGSQDIVEASTTSCLWLGTSDMARGHLVGFPARMHLKTEPDYRQQACTPHLGHGMLGTNPYSRDTVGSCREHAPLYSAHCTCLDPEPPHHLFMCSHSESQHPSLDQDCRAPIVKREPLDSPSWAAPGQVTVPRMFPKSASKTVIPSKGSDGIFLP

Ahrr

Aryl hydrocarbon receptor repressor

701 amino acids

Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

77.799 kDa

MMIPSGECTYAGRKRRKPIQKRRLTMGTEKSNPSKRHRDRLNTELDHLASLLPFSPDIISKLDKLSVLRLSVSYLRVKSFFQALQETCVWSAPALSPEDHSSRGFPVQEGRLLLESLNGFALVVSAEGMIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQSPHADTDNTVLGKLLRAQEGGKGLPSEYSAFLTRCFICRVRCLLDSTSGFLTMQFQGKLKFLFGQKKKTPSGTALPPRLSLFCIVAPVLPSVTEMKMKSAFLKAKHRADIVVTMDSRAKAVTSLCESELHPKLNYLAGRSNGENVISLFRGQTDRSHWTRALARSSCLCLRGGPDLLDPKGTSGDREEDDQKHILRRSPGARGQREMHKYSYGLETPVHLRHLDWSTEQRSQEGTTKLTRQPSKSEPSTCLVPHGSCVPYPGSQGMFSASNMASFRESLDHPTGTYCSQMNRPLPDIHQGQVDPSTCHIPQGSLGSRIPLSGMQCFTARGFSTEDAKLPSLPVNIGTPCNPVLSLEVPIKMENESGSQDIVEASTTSCVWLGTGDMTRRHLVGFPARMHLKTEPDYRQQVCTPHRGHGILGTNPHSRDTVGSCREHAPLYSAHCTCLSPEPPHHLFMCSHSESQHPSLDQDCRAPIVKREPLDSPSWAAPGHVTVPRMFPKNASITVIPSKGSDGIFLP