Protein
PAP-specific phosphatase HAL2-like
Organism
Arabidopsis thaliana
Function
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation.
Similarity
Belongs to the inositol monophosphatase superfamily.
Sequence
MAVDSLETEIDTAVRVVHLASSLCVKVQEKLHLPNGGHVKSKDDDSPVTVADFGVQAIVSWVLAEVFGDQNLSIVAEEDTETLSEADSLGLLGAVSNAVNEALSEAQNYGLPKPVKPLGSSEILKAISRCNSVGGPKGRHWVLDPVDGTLGFVRGDQYAVALALIENGKVLLGVLGCPNYPVKKECLSNGCNQAMKTKAVAGSVSKGCVMYAKRGSGQAWMQPLIVGGIPESATLLKVSSVDDPVLATVCEPVERANSNHLFTAGLANSMGVRKQPMRVYSMVKYAAIARGDAEVFMKFAQSSYKEKIWDHAAGVVIVEEAGGVVTDAGGRNLDFSKGVYLEGLDRGIIACSGQVLHEKIIGAVYASWESSSL