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AGP-SYPU1

Gene
AGP-SYPU1
Protein
Neurotoxin BmK AGP-SYPU1
Organism
Mesobuthus martensii
Length
66 amino acids
Function
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission (By similarity). This toxin has a strong analgesic effect when administered to mice by intraperitoneal injection.
Similarity
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
Mass
7.539 kDa
Fragment
single
Sequence
GRDAYIAQNYNCVYHCFRDDYCNGLCTENGADSGYCYLAGKYGHACWCINLPDDKPIRIPGKCHRR