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AGD5

Gene
AGD5
Protein
ADP-ribosylation factor GTPase-activating protein AGD5
Organism
Arabidopsis thaliana
Length
483 amino acids
Function
GTPase-activating protein (GAP) for ADP ribosylation factor (ARF) (PubMed:19429787). Mediates clathrin-dependent trafficking of vacuolar cargo from the trans-Golgi network (TGN) (PubMed:23771894). Promotes plant growth (PubMed:23771894, PubMed:25763490). Involved in the regulation of membrane trafficking and cell separation during floral organ shedding and abscission (PubMed:19429787, PubMed:20081191, PubMed:20230490, PubMed:23963677). Prevents abscission zone (AZ) cells enlargement (PubMed:23963677, PubMed:25763490). Exhibits ARF-GTPase activity toward ARF1 at TGN (PubMed:21105926).
Mass
52.593 kDa
Sequence
MNEKANVSKELNARHRKILEGLLKHPENRECADCKTKGPRWASVNLGIFICMQCSGIHRSLGVHISKVRSATLDTWLPEQVAFIQSMGNDKANSYWEAELPPNYDRVGIENFIRAKYEEKRWVSRGEKARSPPRVEQERRKSVERSGPGYEHGHSSSPVNLFEERKTIPASRTRNNVAATRINLPVPPQGPSQVIKPQQKMESAATPVEREKQAVNVAPASDPPKVDFATDLFNMLSMDDSTTNTSEATPGDTPADDNSWAGFQSAGSGQTAEKIVTAKPAESSSPPASSSDFEDLFKDTPNLTTQQAPKDVKGDIMSLFEKTNIVSPFAMHQQQVAMLAQQQALYMAAAKAAGGTPNGVNQQAIANALNVASANWSNPGGYQIPGMTNPVGGQADLQKLMQNMNMNANMNTRPAQPQENTLQYPSSSFYTMGQANQVNGMTPNSTGKPQSSSATQPTSTTPSSQSGKDFDFSSLMDGMFTKH