Protein
Tetratricopeptide repeat protein 30 homolog
Organism
Anopheles gambiae
Function
Required for polyglutamylation of axonemal tubulin in sensory cilia. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
Similarity
Belongs to the TTC30/dfy-1/fleer family.
Sequence
MFSQNMIIRDGEYTKTIYTMIKEERFQDAINTLNTIPESSTTRAGLSLLGHCYYQTQDFIEAANCYEHLLNLVPDVQEYRLYYAQSLFQAGLFEEAQKIIATGLDSPELKEKVLQLQSAIAYGNEDYTAAQSLLLQRQDGNGQEASTKNDEGCLLYQANMYEDALQRYVSALQAGGFNPHVAYNAALCHYRRKENSQALNYIAEIVERGIRNHPELGVGAQAETEGGARSVGNPPALAASGLAQAFNLKAAIEYQEGNADGAREALTDLPPRSEPELDPVTLHNMALTDPTGGGAGLRRLAFLLELGPPACPPETFANLLLLCCKHEMYDTAADILAEHTHLTYKYLSPYLYDLLDALITAQSTPEEAEQKLGTLASSIGGRLRALAAKVQECRSATDQNALRMALREYEGALESYLPVAMARAWIPWRMDDFQGAEREFRASAEFCSETPSWRLHAAHVLFMRGDRYKEAAAFYEPIVRQNYDDILSIPASVLANLCVAYIMTSQNEEAEELMRKVERAEERKGNATGQCLHLCIVNLVIGTLYCAKNNYEFGLSRIAHALDGGSGARLCADTWIHVKRCVLGLLTGMAKQTIVLPSIALQETLNFLRACEAYGLTIPSVLTGPLEDSGEQPPTIGLEARKLRALLLRLMEYK