Protein
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Function
Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.
Similarity
Belongs to the HTP reductase family.
Sequence
MRPYVFVNVAASLDGKISDESRKQLRISCEEDLRIVDRLRAESDAIMVGIGTVLADDPRLTVKSAELREKRQKDGKEPNPLRVVVDSRCRVPLTARILNDEARTLVAVSRIAPEEKVREVKKVAEVAVFGEERVELSALLEFLHRKGVRRLMVEGGGTLISSLISQNLVDEIRIYYGPIFIGGRDSPTVCDGESFLKKCRIEKIERIGEGFAVTARFNR