ACSF3

Acyl-CoA synthetase family member 3, mitochondrial

586 amino acids

Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates (By similarity).

Belongs to the ATP-dependent AMP-binding enzyme family.

64.99 kDa

MPLPYVGMALRRLAWAVASCRLAPWTRGASGPLHSAPAARSDCSAPVFIRAPAFGDRLALIDQHGRHTYKDLYLRSLRLSREICQLRACADGDLREERVSLLCSNDVSFVVAQWAAWMSGGVAVPLYRKHPRAQLEYFIQDSRSSVVLAGPEHVELLSPVAQKLGVPLLPLPPTVYHGVAEDPEEGLVLERNWRDRGAMIIYTSGTTGRPKGVLSTHDNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNKLLCPLWVGATCVMLPEFSAQLVWEKFLSSEAPQINVFMAVPTIYSKLMDYYDKHFTQPHVQDFVRAVCEEKIRLMVSGSAALPLPVLEKWKGITGHTLLERYGMTEIGMALSNPLTAARLPGSVGTPLPGVEVRIVSENPQKDSSPYLIHAEGSEENTKVTPGFEEKEGELLVRGPSVFREYWDKPEETKAAFTSDGWFKTGDTVVFKDGCYWIRGRTSVDIIKSGGYKVSALEVERLLLAHPSITDVAVIGVPDMTWGQRVTAVVTLQEGHSLSHRELKEWARGVLAPYAVPSELLLVEEIPRNQMGKVNKRDLVRQLYPHEKGAPEAGSQ

Acsf3

Acyl-CoA synthetase family member 3, mitochondrial

583 amino acids

Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates (By similarity).

Belongs to the ATP-dependent AMP-binding enzyme family.

65.077 kDa

MPPHLALPFRRLFWSLASSQLIPRRHRGHSLLPTTPEAHTDGSVPVFIRALAFGDRIALIDKYGHHTYRELYDRSLCLAQEICRLQGCKVGDLQEERVSFLCSNDVSYVVAQWASWMSGGVAVPLYWKHPEAQLEYFIQDSRSSLVVVGQEYLERLSPLAQRLGVPLLPLTPAVYHGATEKPTEQPVEESGWRDRGAMIFYTSGTTGRPKGALSTHRNLAAVVTGLVHSWAWTKNDVILHVLPLHHVHGVVNKLLCPLWVGATCVMLPEFSAQQVWEKFLSSEAPQITVFMAVPTVYSKLLDYYDKHFTQPHVQDFVRAVCKERIRLMVSGSAALPVPLLEKWRSATGHTLLERYGMTEIGMALSNPLTEARVPGSVGTPLPGVEVRIISENPQKGSPYIIHAEGNERGTKVTPGFEEKEGELLVRGPSVFREYWDKPEETKSAFTSDGWFRTGDTAVFKDARYWIRGRTSVDIIKTGGYKVSALEIERHLLAHPSITDVAVIGVPDMTWGQRVTAVVALQEGHSLSHGDLKEWARGVLAPYAVPSELLLVEEIPRNQMGKVNKKELLKQLYPSGQRSQPGQG

acsf3

Acyl-CoA synthetase family member 3, mitochondrial

578 amino acids

Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. May have some preference toward very-long-chain substrates (By similarity).

Belongs to the ATP-dependent AMP-binding enzyme family.

64.557 kDa

MRVGAFLGRSLFSCSHVRGALVRRRTPQHSCSFHISKPRSLSHVVPVFSRAPLFSERTAMVDQHGKHTYKDLYIRSQALSKMIIQLLGNPSHNNTPERVSFLCPNNSSYVVCQWAVWMSGAIAVPLCKSHPPSELKYVLQDSQSALVVAEESYTNVLSPLAEQLGIPVLTMSGSQNLHPSELLQEIKISQLDLDWKDRGAMIIYTSGTTGRPKGVLSTHYNLYSMVTALVNEWGWTKEDSILHVLPLHHVHGVVNKLMCPLWVGATCVILPEFCPKTVWQHFLGRDVPSINIFMAVPTIYSKLIAYYEQHFTHSNVREFVRAACQERIRLMVSGSSALPVPVLERWQEITGHTLLERYGMTEIGMALTNPLHGPRVPGAVGAPLPGVEVRTVTQNPRKEGTSYTTHAQGDSTGTMVSVGLENREGELQVRGPAVFKEYWNKRLDTQEAFTSDGWFKTGDTAMYKDGTYWILGRTSVDIIKSGGYKVSALEVERHLLGHPSITDVAVIGAPDVTWGQRVAAIVKLRDGHALSLQELKEWARAVMAPYCIPAELIRVEEIPRNQMGKINKKQLLVHFYPQ

ACSF3

Acyl-CoA synthetase family member 3, mitochondrial

576 amino acids

Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates.

Belongs to the ATP-dependent AMP-binding enzyme family.

64.13 kDa

MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALVDQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS

acsF3

Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 3

358 amino acids

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).

Belongs to the AcsF family.

42.298 kDa

MVDSLKKPGFEEIRPGVKVPAKETLLTPRFYTTDFDEMARMDISVNEDELLAILEEFRTDYNRHHFVRDAEFEKSWDHIDGDTRRLFVEFLERSCTAEFSGFLLYKELGRRLKDKSPVLAECFNLMSRDEARHAGFLNKAMSDFNLSLDLGFLTKSRNYTFFKPKFIFYATYLSEKIGYWRYITIYRHLEAHPEDRIYPIFRFFENWCQDENRHGDFFDAIMKSQPQMLNDWKAKLWSRFFLLSVFATMYLNDIQRKDFYATIGLDARDYDIYVIKKTNETAGRVFPIILDVDSPEFYERLDICVENSEKLSAIASSNTPKFLQFFQKLPVLASTGWQLLRLYLMKPIDAVSAQGAAR