Protein
Methionine aminopeptidase 2-2
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Function
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
Similarity
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
Sequence
MAAQTTEKLQKLDLNGQSGDAKADAPAAGQAEAGEAEEDSDDEKDDGNAAPEAGAGGAAKKKKRKSKKKKKGGAKVQSSPPRVPVSNLFPNNQYPEGEIVEYTNENSYRTTNEEKRYLDRMNNDFLQEYRQAAEVHRQVRQYAQKNIKPGQTLTEIAEGIEDAVRALTGHQGLEEGDNLKGGMGFPCGLSINHCAAHYTPNAGNKMVLQQGDVMKVDFGAQINGRIVDSAFTMTFDPVYDPLLEAVKDATNTGIREAGIDVRMSDIGAAIQEAMESYEIELNGTMYPVKCIRNLNGHNIDQHVIHGGKSVPIVKGGDQTKMEEGETFAIETFGSTGKGYVREDMETSHYALVPDAPSVPLRLSSAKNLLNVINKNFGTLPFCRRYLDRLGQDKYLLGLNNLVSSGIVQDYPPLCDIKGSYTAQFEHVQIPSHSHP