ACA1

Calcium-transporting ATPase 1, plasma membrane-type

1043 amino acids

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell, into the endoplasmic reticulum, or into organelles.

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.

112.842 kDa

MSFIRKKSMEFLKSFEVPAKNPSEEAQRRWRDAVGTLVKNRRRRFRMVPDLDKRSQAETQRRKIQEKLRVALFVQKAALQFIDAVRKTEHPLPELARQCGFSVSAEELASIVRGHDTKSLRFHNGVDGIARKVAVSLADGVKSDDAGLRAEVYGANQYTEKPPRTFWMFLWDASQDMTLLLLAFCAAVSVAIGLATEGWPSGMYDGVGIMLTILLVVMITAASDYKQSLQFRDLDKEKKKIDVQVTRDGYRQKVSIYDIVVGDIVHLSIGDQVPADGLFIDGYSFVVDESNLSGESEPVHVSTANRFLLGGTKVQDGSARMLVTAVGMRTEWGNLMETLSQGGEDETPLQVKLNGVATIIGKIGLAFAVLTFTVLMARFLLGKAGAPGGLLRWRMVDALAVLNFFAVAVTIIVVAVPEGLPLAVTLSLAFAMKKLMQERALVRHLSACETMGSASCICTDKTGTLTTNHMVVEKIWASGAAQTMSNAKGFDQLTSSMSETFAKVLLEGVFHCSGSEVVRGKDGRHTIMGTPTETAILEFGLAVEKRARIEHTGAGKLKVEPFNSVKKTMAVVIASPSAGGRPRAFLKGASEVVLSRCSLVLDGTGNVEKLTDAKAKRVASAIDAFACEALRTLCLAYQDVDGGGGDIPGEGYTLIAVFGIKDPLRPGVREAVATCHAAGINVRMVTGDNINTAKAIARECGILTDDGIAIEGPEFRNKDPDQMREIIPKIQVMARSLPLDKHTLVTNLRGMFNEVVAVTGDGTNDAPALHEADIGLAMGIAGTEVAKENADVIIMDDNFSTIINVAKWGRSVYINIQKFVQFQLTVNVVALMVNFISASFTGSAPLTIVQLLWVNLIMDTLGALALATEPPNDAMMKRPPVGRGDNFITKVMWRNIVGQSIYQLVVLGVLLLRGKSLLQINGPQADSLLNTFVFNTFVFCQVFNEVNSREMEKINVFSGIFSSWIFSAVVGVTAGFQVIMVELLGTFANTVHLSGKLWLTSVLIGSVGLVIGAILKCIPVESGSDASDRHDGYRPIPTGPSAV

ACA1

Calcium-transporting ATPase 1

1020 amino acids

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell or into organelles.

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.

111.261 kDa

MESYLNENFGDVKPKNSSDEALQRWRKLCWIVKNPKRRFRFTANLSKRSEAEAIRRSNQEKFRVAVLVSQAALQFINSLKLSSEYTLPEEVRKAGFEICPDELGSIVEGHDLKKLKIHGGTEGLTEKLSTSIASGISTSEDLLSVRKEIYGINQFTESPSRGFWLFVWEALQDTTLMILAACAFVSLIVGILMEGWPIGAHDGLGIVASILLVVFVTATSDYRQSLQFKDLDAEKKKIVVQVTRDKLRQKISIYDLLPGDVVHLGIGDQIPADGLFISGFSVLINESSLTGESEPVSVSVEHPFLLSGTKVQDGSCKMLVTTVGMRTQWGKLMATLSEGGDDETPLQVKLNGVATIIGKIGLFFAVITFAVLVQGLANQKRLDNSHWIWTADELMAMLEYFAVAVTIVVVAVPEGLPLAVTLSLAFAMKKMMNDKALVRNLAACETMGSATTICSDKTGTLTTNHMTVVKACICEQAKEVNGPDAAMKFASGIPESAVKLLLQSIFTNTGGEIVVGKGNKTEILGTPTETALLEFGLSLGGDFQEVRQASNVVKVEPFNSTKKRMGVVIELPERHFRAHCKGASEIVLDSCDKYINKDGEVVPLDEKSTSHLKNIIEEFASEALRTLCLAYFEIGDEFSLEAPIPSGGYTCIGIVGIKDPVRPGVKESVAICKSAGITVRMVTGDNLTTAKAIARECGILTDDGIAIEGPEFREKSDEELLKLIPKLQVMARSSPMDKHTLVRLLRTMFQEVVAVTGDGTNDAPALHEADIGLAMGISGTEVAKESADVIILDDNFSTIVTVAKWGRSVYINIQKFVQFQLTVNVVALIVNFLSACLTGNAPLTAVQLLWVNMIMDTLGALALATEPPQDDLMKRSPVGRKGNFISNVMWRNILGQSLYQLVIIWCLQTKGKTMFGLDGPDSDLTLNTLIFNIFVFCQVFNEISSREMEKIDVFKGILKNYVFVAVLTCTVVFQVIIIELLGTFADTTPLNLGQWLVSIILGFLGMPVAAALKMIPVGSH

ACA1

ATF/CREB activator 1

489 amino acids

Transcriptional activator of promoters containing ATF/CREB sites. Can independently stimulate transcription through ATF/CREB sites. Important for a variety of biological functions including growth on non-optimal carbon sources. Regulates the expression of COS8. Has efficient silencing blocking activities.

Belongs to the bZIP family.

54.592 kDa

MDYKHNFATSPDSFLDGRQNPLLYTDFLSSNKELIYKQPSGPGLVDSAYNFHHQNSLHDRSVQENLGPMFQPFGVDISHLPITNPPIFQSSLPAFDQPVYKRRISISNGQISQLGEDLETVENLYNCQPPILSSKAQQNPNPQQVANPSAAIYPSFSSNELQNVPQPHEQATVIPEAAPQTGSKNIYAAMTPYDSNIKLNIPAVAATCDIPSATPSIPSGDSTMNQAYINMQLRLQAQMQTKAWKNAQLNVHPCTPASNSSVSSSSSCQNINDHNIENQSVHSSISHGVNHHTVNNSCQNAELNISSSLPYESKCPDVNLTHANSKPQYKDATSALKNNINSEKDVHTAPFSSMHTTATFQIKQEARPQKIENNTAGLKDGAKAWKRARLLERNRIAASKCRQRKKMSQLQLQREFDQISKENTMMKKKIENYEKLVQKMKKISRLHMQECTINGGNNSYQSLQNKDSDVNGFLKMIEEMIRSSSLYDE

ACA1

Alpha carbonic anhydrase 1, chloroplastic

284 amino acids

Reversible hydration of carbon dioxide.

Belongs to the alpha-class carbonic anhydrase family.

32.698 kDa

MKIMMMIKLCFFSMSLICIAPADAQTEGVVFGYKGKNGPNQWGHLNPHFTTCAVGKLQSPIDIQRRQIFYNHKLNSIHREYYFTNATLVNHVCNVAMFFGEGAGDVIIENKNYTLLQMHWHTPSEHHLHGVQYAAELHMVHQAKDGSFAVVASLFKIGTEEPFLSQMKEKLVKLKEERLKGNHTAQVEVGRIDTRHIERKTRKYYRYIGSLTTPPCSENVSWTILGKVRSMSKEQVELLRSPLDTSFKNNSRPCQPLNGRRVEMFHDHERVDKKETGNKKKKPN

aca1

N-acetyltransferase aca1

209 amino acids

N-acetyltransferase involved in oxidative stress resistance. Acetylates the toxic proline metabolism intermediate (S)-1-pyrroline-5-carboxylate (P5C), or more likely its spontaneously forming tautomer glutamate-5-semialdehyde (GSA) into N-acetyl-GSA for arginine synthesis in the mitochondria. P5C has been shown to increase the levels of reactive oxigen species (ROS) in the cell by inhibiting the function of the respiratory chain in the mitochondria. The enzyme is able to reduce intracellular ROS levels under P5C-induced oxidative stress and protects cells from damage by oxidative stress (By similarity). Also acetylates and thereby detoxifies the proline analog azetidine-2-carboxylate (AZC), however it is unlikely that AZC is a natural substrate as it occurs only in plants belonging to the Lilaceae family (PubMed:12761200).

Belongs to the acetyltransferase family.

23.809 kDa

MKDPNTIPPWRCTDFNAWCIAVDKSTNVKNKEELLSTLTYFINYEIEMGQTYPIDIKMTRNEAEDFFFKFCTVICVPVESETSPAPDLATASIDWKTSLLGAFYIKPNYPGRCSHICNGGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSSVFNLVFATNIKSIRLWERLNFTRAGIIKDAGRLKGHEGYVDAYIYQYHFPSLEDALK