Protein
Adenylosuccinate synthetase
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Function
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
Similarity
Belongs to the adenylosuccinate synthetase family.
Sequence
MVNVVLGSQWGDEGKGKLVDLLVSKYDIVARSAGGNNAGHTIVVGGIKYDFHMLPSGLVNPNCQNLIGNGVVIHVPSFFGELEQLEAKGLRDARGRLFISSRAHLVFDFHQRTDKLRELELSGKSKDGKNIGTTGKGIGPTYSTKASRSGLRVHHLVSEQPEAWAEFETKYRRLLETRQQRYGPFEHDAEEELARYRRYREELRPFVVDSVVFMHNAIQQKKKILVEGANALMLDIDFGTYPYVTSSSTGIGGVLTGLGIPPRCIDEIYGVVKAYTTRVGEGPFPTEQLNEAGDKLQTIGAEYGVTTGRKRRCGWLDLVVLKYSTLINGFTSLNITKLDVLDTFKEIKVGISYSLNGKKLDLFPEDLLVLSKVDVEYVTLPGWDEDITKISRYEDLPENAKSYLKFIEDFVGVPVEWVGTGPGRESMLHKEVS