ABHD17B

Gene

ABHD17B

Protein

Alpha/beta hydrolase domain-containing protein 17B

Organism

Gallus gallus

Length

288 amino acids

Function

Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS.

Similarity

Belongs to the AB hydrolase superfamily. ABHD17 family.

Mass

32.201 kDa

Sequence

MNNLSFSELCCLFCCPPCPGKIASKLAFLPPDPTYTLMCDESGSRWTLHLSERADWQYSSREKDAIECFMTRTSKGNRIACMFVRCSPNAKYTLLFSHGNAVDLGQMSSFYIGLGSRINCNIFSYDYSGYGASSGKPSEKNLYADIDAAWVALRTRYGIRPENVIIYGQSIGTVPSVDLAARYESAAVILHSPLTSGMRVAFPDTKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDVELYGQYLERLKRFVSQELVNL

Protein

Alpha/beta hydrolase domain-containing protein 17B: ABHD17B

Gene

ABHD17B

Protein

Alpha/beta hydrolase domain-containing protein 17B

Organism

Homo sapiens

Length

288 amino acids

Function

Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (PubMed:26701913). Has depalmitoylating activity towards DLG4/PSD95 (PubMed:26701913). Has depalmitoylating activity towards GAP43 (By similarity). Has depalmitoylating activity towards MAP6 (By similarity). Has depalmitoylating activity towards NRAS (PubMed:26701913).

Similarity

Belongs to the AB hydrolase superfamily. ABHD17 family.

Mass

32.215 kDa

Sequence

MNNLSFSELCCLFCCPPCPGKIASKLAFLPPDPTYTLMCDESGSRWTLHLSERADWQYSSREKDAIECFMTRTSKGNRIACMFVRCSPNAKYTLLFSHGNAVDLGQMSSFYIGLGSRINCNIFSYDYSGYGASSGKPTEKNLYADIEAAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYESAAVILHSPLTSGMRVAFPDTKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDVELYGQYLERLKQFVSQELVNL

Protein

Alpha/beta hydrolase domain-containing protein 17B: ABHD17B

Gene

Abhd17b

Protein

Alpha/beta hydrolase domain-containing protein 17B

Organism

Mus musculus

Length

288 amino acids

Function

Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (PubMed:27307232). Has depalmitoylating activity towards DLG4/PSD95 (PubMed:27307232). Has depalmitoylating activity towards GAP43 (PubMed:27307232). Has depalmitoylating activity towards MAP6 (PubMed:28521134). Has depalmitoylating activity towards NRAS (By similarity).

Similarity

Belongs to the AB hydrolase superfamily. ABHD17 family.

Mass

32.201 kDa

Sequence

MNNLSFSELCCLFCCPPCPGKIASKLAFLPPDPTYTLMCDESGSRWTLHLSERADWQYSSREKDAIECFMTRTSKGNRIACMFVRCSPNAKYTLLFSHGNAVDLGQMSSFYIGLGSRINCNIFSYDYSGYGASSGKPTEKNLYADVEAAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYESAAVILHSPLTSGMRVAFPDTKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDVELYGQYLERLKQFVSQELVNL

Protein

Alpha/beta hydrolase domain-containing protein 17B: Abhd17b

Gene

Abhd17b

Protein

Alpha/beta hydrolase domain-containing protein 17B

Organism

Rattus norvegicus

Length

288 amino acids

Function

Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards DLG4/PSD95. Has depalmitoylating activity towards GAP43. Has depalmitoylating activity towards MAP6. Has depalmitoylating activity towards NRAS.

Similarity

Belongs to the AB hydrolase superfamily. ABHD17 family.

Mass

32.201 kDa

Sequence

Protein

Alpha/beta hydrolase domain-containing protein 17B: Abhd17b

Gene

abhd17b

Protein

Alpha/beta hydrolase domain-containing protein 17B

Organism

Xenopus laevis

Length

288 amino acids

Function

Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards nras.

Similarity

Belongs to the AB hydrolase superfamily. ABHD17 family.

Mass

32.209 kDa

Sequence

MNNLSFSELCCLFCCPPCPGKIASKLAFLPPDPTYTLICDESGSRWTLHLSERADWQYSSREKDAIECFMTRTSRGNRIACMFVRCCPSAKYTLLFSHGNAVDLGQMSSFYIGLGSRINCNIFSYDYSGYGSSSGKPSEKNLYADIDAAWIALRTRYGIRPEHVIIYGQSIGTVPSVDLAARYESAAVILHSPLTSGMRVAFPDTKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDVELYGQYLERLKQFVAQELVNL

Protein

Alpha/beta hydrolase domain-containing protein 17B: abhd17b

Gene

abhd17b

Protein

Alpha/beta hydrolase domain-containing protein 17B

Organism

Xenopus tropicalis

Length

288 amino acids

Function

Hydrolyzes fatty acids from S-acylated cysteine residues in proteins.

Similarity

Belongs to the AB hydrolase superfamily. ABHD17 family.

Mass

32.25 kDa

Sequence

MNNLSFSELCCLFCCPPCPGKIASKLAFLPPDPTYTLICDESGSRWTLHLSERADWQYSSREKDAIECFMTRTSRGNRIACMFVRCSPNAKYTLLFSHGNAVDLGQMSSFYIGLGSRINCNIFSYDYSGYGSSSGKPSEKNLYADIDAAWIALRTRYGIRPEHVIIYGQSIGTVPSVDLAARYESAAVILHSPLTSGMRVAFPDTKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDVELYGQYLERLKQFVTQELVNL

Protein

Alpha/beta hydrolase domain-containing protein 17B: abhd17b