ABCB11

Bile salt export pump

1321 amino acids

Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner (PubMed:16332456). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (PubMed:16332456).

Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.

146.407 kDa

MSDSVILRSIKKFGEENDGFESDKSYNNDKKSRLQDEKKGDGVRVGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQIPGKACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICFWVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMALFIQRMTSTICGFLLGFFRGWKLTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVADEVISSMRTVAAFGGEKREVERYEKNLVFAQRWGIRKGIVMGFFTGFVWCLIFLCYALAFWYGSTLVLDEGEYTPGTLVQIFLSVIVGALNLGNASPCLEAFATGRAAATSIFETIDRKPIIDCMSEDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNDLNMVIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHEELLERKGVYFTLVTLQSQGNQALNEEDIKDATEDDMLARTFSRGSYQDSLRASIRQRSKSQLSYLVHEPPLAVVDHKSTYEEDRKDKDIPVQEEVEPAPVRRILKFSAPEWPYMLVGSVGAAVNGTVTPLYAFLFSQILGTFSIPDKEEQRSQINGVCLLFVAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTRLATDASQVQGAAGSQIGMIVNSFTNVTVAMIIAFSFSWKLSLVILCFFPFLALSGATQTRMLTGFASRDKQALEMVGQITNEALSNIRTVAGIGKERRFIEALETELEKPFKTAIQKANIYGFCFAFAQCIMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRAFSYTPSYAKAKISAARFFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTYPSRPDSQVLNGLSVSISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNADIIAVMAQGVVIEKGTHEELMAQKGAYYKLVTTGSPIS

Abcb11

Bile salt export pump

1321 amino acids

Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner. Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts.

Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.

146.749 kDa

MSDSVILRSVKKFGEENHAFESDGFHNNDKKSRLQDKKKGEGARVGFFELFRFSSSKDNWLMFMGSVCALLHGMAQPGMIIVFGILTDIFVEYDIERQELSIPEKVCMNNTIVWINSSFNQNMTNGTSCGLVDINSEVIKFSGIYAGVGVAVLILGYFQIRLWVITGARQIRKMRKFYFRRIMRMEIGWFDCTSVGELNSRFSDDINKIDEAIADQMALFLQRLSTALSGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSVAKFTELELKAYAKAGSIADEVLSSIRTVAAFGGENKEVERYEKNLMFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYGSRLVLDEGEYTPGTLIQIFLCVIIAAMNIGNASSCLEIFSTGCSAASSIFQTIDRQPVMDCMSGDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNNLSMVIKPGETTAFVGSSGAGKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRLGREEATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRKPKILLLDMATSALDNESEAKVQGALNKIQHGHTIISVAHRLSTVRSADVIIGFEHGTAVERGTHEELLERKGVYFMLVTLQSQEDNTHKETGIKGKDTTEGDTPERTFSRGSYQDSLRASIRQRSKSQLSHLSHEPPLAIGDHKSSYEDRKDNDVLVEEVEPAPVRRILKYNISEWPYILVGALCAAINGAVTPIYSLLFSQILKTFSLVDKEQQRSEIYSMCLFFVILGCVSLFTQFLQGYNFAKSGELLTKRLRKFGFKAMLRQDIGWFDDLKNNPGVLTTRLATDASQVQGATGSQVGMMVNSFTNIFVAVLIAFLFNWKLSLVISVFFPFLALSGAVQTKMLTGFASQDKEILEKAGQITNEALSNIRTVAGIGVEGRFIKAFEVELEKSYKTAIRKANVYGLCYAFSQGISFLANSAAYRYGGYLIVYEDLNFSYVFRVVSSIAMSATAVGRTFSYTPSYAKAKISAARFFQLLDRKPPIDVYSGAGEKWDNFQGKIDFIDCKFTYPSRPDIQVLNGLSVSVDPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNVQFLRSNIGIVSQEPVLFDCSIMDNIKYGDNTKEISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQLALDKAREGRTCIVIAHRLSTIQNSDIIAVMSQGVVIEKGTHKKLMDQKGAYYKLVITGAPIS

ABCB11

Bile salt export pump

1321 amino acids

Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner. Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts.

Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.

146.377 kDa

MSDSVILRSVKKFGEENHGFESDGSYNNEKKSRLQDKKKSDSVRIGFFQLFRFSSWTDIWLMCMGSLCACIHGIAQPGVLLIFGTMTDVFIDYDTELQELKIPGKACVNNTIVWINSSLNQNVTNGTRCGLLDIESEMIRFAGYYAGIGIAVLTTGYIQICFWGIAAAHQIQKMRKSYFRKIMRMGIGWVDCNSVGKLNTPFSVDFNKINDSSADQLAIFIQGMTSPIFGFLVGFSQWWKLTLVIISVSPLIGLGAAIIGLSVSKFTDYELKAYAKAGSVADEVISSMRTVAAFGGEKKEVERYEKNLVFAQRWGIRKGIVMGFFTGYMWCLIFFCYALAFWYGSKLVLEEGEYSPGALVQIFLSVIIGALNLGNASPCLEAFAAGRAAASSIFETIDRKPIIDCMSEDGYKLERIKGEIEFHNVTFHYPSRPEVKILNNLSMVIKPGEMTALVGPSGAGKSTALQLIHRFYGPTEGMVTVESHDIRSSHIQWLRNQIGIVEQEPVLFFHTIAEKIRYGREDATMEDLIQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEALSKTQHGHTIVSVAHRPATIRTADVIIGCEHGAAVERGTEEELLERKGVYFALVTLQSQRNQGDQEENEKDATEDDIPEKTFSRGNYQDSLRASLRQRSKSQLSYLAHEPPMAVEDHKSTHEEDRKDKDLPAQEDIEPASVRRIMKLNAPEWPYMLLGSMGAAVNGAVTPLYAFLFSQILGTFSLPDKEEQRSQINGICLLFVTLGCVSFFTQFLQGYTFAKSGELLTKRLRKFGFRAMLGQDIGWFDDLRNSPGALTTRLATDASQVQGATGSQIGMMVNSFTNVTVAMIIAFLFSWKLTLGIVCFFPFLALSGALQTKMLTGFASRDKQALEKAGQITSEALSNIRTVAGIGKERKFIETFEAELEKPYKMAIKKANVYGLCFGFSQCITFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSATALGRASSYTPSYAKAKISAARFFQLLDRQPPINVYSSAGEKWDNFQGKIDFVDCKFTYPSRPDIQVLNGLSVSMSPRQTLAFVGSSGCGKSTSIQLLERFYDPDHGKVMIDGHDSRKVNIQFLRSNIGIVSQEPVLFACSIKDNIKYGDNTQEIPMERIIAAAKKAQVHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNSDIIAVMSQGMVIEKGTHEELMVQKGAYYKLVTTGSPIS

Abcb11

Bile salt export pump

1321 amino acids

Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner (PubMed:16332456). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (PubMed:16332456).

Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.

146.258 kDa

MSDSVILRSVKKFGEENHAFESDGSHNNDKKSRLQDKMKEGDIRVGFFELFRFSSSKDIWLMLMGGVCALLHGMAQPGILIIFGIMTDIFIKYDIERQELEIPGKACVNNTIVWINSSFHQNMTNGTVCGLVDIESEMIKFSGIYAGVGMTVLILGYFQIRLWVITGARQIRRMRKIYFRRIMRMEIGWFDCTSVGELNSRFADDIEKINDAIADQLAHFLQRMSTAMCGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSIAKFTELELKAYAKAGSIADEVLSSIRTVAAFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWCLIFFCYALAFWYGSTLVLDEEEYTPGTLVQIFLCVILAAMNIGHASSCLEIFSTGCSAATNIFQTIDRQPVIDCMSGDGYKLDRIKGEIEFHNVTFHYPSRPDVKILDNLSMVIKPGETTALVGSSGAGKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLFSTTIAENIRFGREDATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEARVQEALNKIQHGHTIISVAHRLSTVRAADVIIGFEHGVAVERGTHEELLERKGVYFMLVTLQSQGDNAHKETSIMGKDATEGGTLERTFSRGSYRDSLRASIRQRSKSQLSLLTHDPPLAVADHKSSYKDSKDNDVLVEEVEPAPVRRILKYNIPEWHYILVGSLSAAINGAVTPIYSLLFSQLLGTFSLLDKEQQRSEIHSMCLFFVILGCVSIFTQFLQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGVLTTRLATDASQVQGATGSQVGMMVNSFTNIIAALLIAFFFSWKLSLIITIFFPFLALSGAVQTKMLTGFASQDKQALEKAGQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYKTAVRKANIYGLCFAFSQGIAFLANSAAYRYGGYLIAYEGLGFSHVFRVVSSVALSATAVGRTFSYTPSYAKAKISAARFFQLLDRKPPINVYSEAGEKWDNFQGKIDFIDCKFTYPSRPDIQVLNGLSVSVNPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKKVNIQFLRSNIGIVSQEPVLFDCSIMDNIKYGDNTKEISVERAIAAAKQAQLHDFVMSLPEKYETNVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQTALDKAREGRTCIVIAHRLSTIQNSDIIAVVSQGVVIEKGTHEKLMAQKGAYYKLVITGAPIS

ABCB11

ABC transporter B family member 11

1278 amino acids

Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.

137.667 kDa

MNGDGAREGDSVSHEPSTSKSPKEGEETKKEEKSEEKANTVPFYKLFAFADSSDVLLMICGSIGAIGNGMSLPFMTLLFGDLIDSFGKNQNNKDIVDVVSKVCLKFVYLGLGTLGAAFLQVACWMITGERQAARIRSTYLKTILRQDIGFFDVETNTGEVVGRMSGDTVLIQDAMGEKVGKFIQLVSTFVGGFVLAFIKGWLLTLVMLTSIPLLAMAGAAMALIVTRASSRGQAAYAKAATVVEQTIGSIRTVASFTGEKQAINSYKKFITSAYKSSIQQGFSTGLGLGVMFFVFFSSYALAIWFGGKMILEKGYTGGAVINVIIIVVAGSMSLGQTSPCVTAFAAGQAAAYKMFETIKRKPLIDAYDVNGKVLEDIRGDIELKDVHFSYPARPDEEIFDGFSLFIPSGATAALVGESGSGKSTVISLIERFYDPKSGAVLIDGVNLKEFQLKWIRSKIGLVSQEPVLFSSSIMENIAYGKENATVEEIKAATELANAAKFIDKLPQGLDTMVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRVMVNRTTVIVAHRLSTVRNADMIAVIHRGKMVEKGSHSELLKDSEGAYSQLIRLQEINKDVKTSELSSGSSFRNSNLKKSMEGTSSVGNSSRHHSLNVLGLTTGLDLGSHSQRAGQDETGTASQEPLPKVSLTRIAALNKPEIPVLLLGTVAAAINGAIFPLFGILISRVIEAFFKPAHELKRDSRFWAIIFVALGVTSLIVSPTQMYLFAVAGGKLIRRIRSMCFEKAVHMEVAWFDEPQNSSGTMGARLSADATLIRALVGDALSLAVQNVASAASGLIIAFTASWELALIILVMLPLIGINGFVQVKFMKGFSADAKSKYEEASQVANDAVGSIRTVASFCAEEKVMQMYKKQCEGPIKDGIKQGFISGLGFGFSFFILFCVYATSFYAGARLVEDGKTTFNNVFQVFFALTMAAIGISQSSTFAPDSSKAKVAAASIFAIIDRKSKIDSSDETGTVLENVKGDIELRHLSFTYPARPDIQIFRDLCLTIRAGKTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGVELKKLQLKWLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELANAHKFISSIQQGYDTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTIVVAHRLSTIKNADVIAVVKNGVIAEKGTHETLIKIEGGVYASLVQLHMTASN