Organism
Variola virus (isolate Human/India/Ind3/1967)
Function
Plays a role in DNA replication by cleaving viral DNA concatamers to yield unit-length viral genomes. The concatamer junctions contain inverted repeat sequences that can be extruded as cruciforms, yielding Holliday junctions that A22 protein cleaves (By similarity).
Similarity
Belongs to the RuvC family. Poxviruses-type subfamily.
Sequence
METLTSSSQSLISSPMSKKDYSSEIICAFDIGAKNPARTVLEVKDNSVRVLDISKLDWSSDWERRIAKDLSQYEYTTVLLERQPRRSPYVKFIYFIKGFLYHTSATKVICVSPVMSGNSYRDRKKRSVEAFFDWMDIFGLRDSVPDRRKLDDVADSFNLAMRYVLDKWNTNYTHYNRCKSRNYIKKM