Protein
8-hydroxygeraniol dehydrogenase
Organism
Catharanthus roseus
Function
Dehydrogenase involved in the biosynthesis of oxogeranial from hydroxygeraniol, a precursor of the terpenoid indole alkaloids such as vinblastine and vincristine.
Similarity
Belongs to the zinc-containing alcohol dehydrogenase family.
Sequence
MAKSPEVEHPVKAFGWAARDTSGHLSPFHFSRRATGEHDVQFKVLYCGICHSDLHMIKNEWGFTKYPIVPGHEIVGIVTEVGSKVEKFKVGDKVGVGCLVGSCRKCDMCTKDLENYCPGQILTYSATYTDGTTTYGGYSDLMVADEHFVIRWPENLPMDIGAPLLCAGITTYSPLRYFGLDKPGTHVGVVGLGGLGHVAVKFAKAFGAKVTVISTSESKKQEALEKLGADSFLVSRDPEQMKAAAASLDGIIDTVSAIHPIMPLLSILKSHGKLILVGAPEKPLELPSFPLIAGRKIIAGSAIGGLKETQEMIDFAAKHNVLPDVELVSMDYVNTAMERLLKADVKYRFVIDVANTLKSA