Description
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
Family
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Species
Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)
Sequence
MLRLIDSISDNCTVKTALYGALLLGVYKLTTFALSLVSLVLDLWVLPPVNFAKYGAKKGKWAVITGASDGIGKEYATQLAAKGLNVVLVSRTESKLVALAEEIESKYKVSTKVLAFDVSLDAESSYEDLAATIADLPVTVLVNNVGQSHSIPVPFLETDEKELRNIITINNTATLKITQVVAPKIVHTVASEKKKTRGLILTMGSFGGLLPTPYLATYSGSKAFLQSWSNALSGELQPQGVDVELVISYLVTSAMSKIRRSSASIPNPKAFVKSVLRNVGRRVGAQERFGTTTPYWAHAFMHFGIVNSVGVYSKIANSLNLGMHKSIRSRALKKAARQKKD
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service