Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.

Belongs to the AdoMet synthase family.

393 amino acids

MDTFLFTSESVNEGHPDKLCDQISDAILDACLEQDPESKVACETCTKTNMVMIFGEITTKANIDYEKIVRDTCRGIGFVSADVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKKPEEIGAGDQGHMFGYATDETPELMPLTHVLATKLGARLTEVRKDGTCPWLRPDGKTQVTVEYKNEGGAMVPLRVHTVLISTQHDETVTNDEIAADLKEHVIKPVVPSQYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVAAGLARRCLVQVSYAIGVPEPLSVFVDTYGTGTGKIQDAEILKLIKENFDFRPGMISINLDLKRGGNMRFQKTAAYGHFGREDPDFTWETVKVLKWEKA

42.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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